Details for: Phex
Associated with
Other Information
Genular Protein ID: 2197442586
Symbol: PHEX_MOUSE
Name: Metalloendopeptidase homolog PEX
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8812412
Title: cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone.
PubMed ID: 8812412
PubMed ID: 9063736
Title: Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia.
PubMed ID: 9063736
DOI: 10.1093/hmg/6.2.165
PubMed ID: 9077527
Title: Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice.
PubMed ID: 9077527
DOI: 10.1172/jci119276
PubMed ID: 11159866
Title: Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition.
PubMed ID: 11159866
PubMed ID: 11811562
Title: Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts.
PubMed ID: 11811562
PubMed ID: 18597632
Title: MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM.
PubMed ID: 18597632
DOI: 10.1359/jbmr.080601
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 26051469
Title: Age dependent regulation of bone-mass and renal function by the MEPE ASARM-motif.
PubMed ID: 26051469
Sequence Information:
- Length: 749
- Mass: 86419
- Checksum: A88FA481C376C18A
- Sequence:
MEAETGSTME TGKGTNRGIR IALALFIGGT LVLGTLLFLV SQGLLSFQAK QEYCLKPECI EAAAAIMSKV NLSVDPCENF FRFACDGWIS NNPIPEDMPS YGVYPWLRHN VDLKLKALLE KSVSRRRDTE AVQKAKILYS SCMNEKAIEK ADAKPLLHIL RHSPFRWPVL EANIGPEGVW SERKFSLLQT LATFRGQYSN SVFIRLYVSP DDKASNEHIL KLDQATLSLA VREDFLDNTT EAKSYRDALY KFMVDTAVLL GANSSRAEHD MKSVLRLEIK IAEIMIPHEN RTSEAMYNKM NISELSAMIP QFDWLGYIKK VIDTRLYPHL KDIGPSENVV VRVPQYFKDL FRILGAERKK TIANYLVWRM VYSRIPNLSR RFQYRWLEFS RVIQGTTTLL PQWDKCVNFI ESALPYVVGK MFVNVHFQED KKEMMEELIE GVRWAFIDML EKENEWMDAG TKRKAQEKAR AVLAKVGYPE FIMNDTYVNE DLKAIKFSES DYFGNVLQTR KYLAQSDFFW LRKAVPKTEW FTNPTTVNAF YSASTNQIRF PAGELQKPFF WGTEYPRSLS YGAIGVIVGH EFTHGFDNNG RKYDKNGNLD PWWSVESEEK FKEKTKCMIN QYSNYYWKKA GLNVKGKRTL GENIADNGGL REAFRAYRKW INDRRQGVEE PLLPGITFTN NQLFFLSYAH VRCNSYRPEA AREQVQIGAH SPPQFRVNGA ISNFEEFQKA FNCPRNSTMN RGADSCRLW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.