Details for: APLNR
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: glomerular capillary endothelial cell (CL1001005)
Fold Change: 5.4146
Cell Significance Index: 20.1800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.7833
Cell Significance Index: 31.6200 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.5183
Cell Significance Index: 23.4900 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.7204
Cell Significance Index: 12.7300 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 0.6862
Cell Significance Index: 5.0300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.4017
Cell Significance Index: 84.6100 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.2875
Cell Significance Index: 1.8000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.1843
Cell Significance Index: 103.9600 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1754
Cell Significance Index: 1.0600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0715
Cell Significance Index: 44.6500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0029
Cell Significance Index: 0.1500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.0000
Cell Significance Index: 0.0200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0013
Cell Significance Index: -0.2500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0071
Cell Significance Index: -1.2200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0088
Cell Significance Index: -6.6800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0137
Cell Significance Index: -4.9300 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0145
Cell Significance Index: -7.9400 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0200
Cell Significance Index: -2.2800 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0202
Cell Significance Index: -0.2900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0207
Cell Significance Index: -2.6500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0212
Cell Significance Index: -6.0900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0216
Cell Significance Index: -9.7900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0328
Cell Significance Index: -5.9200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0335
Cell Significance Index: -6.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0432
Cell Significance Index: -4.4200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0487
Cell Significance Index: -5.9900 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.0501
Cell Significance Index: -0.7000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0534
Cell Significance Index: -6.1200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0552
Cell Significance Index: -7.1300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0560
Cell Significance Index: -1.5000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0573
Cell Significance Index: -7.8700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0598
Cell Significance Index: -3.0200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0627
Cell Significance Index: -4.8200 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0837
Cell Significance Index: -1.2200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0863
Cell Significance Index: -5.8000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0971
Cell Significance Index: -7.2400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0994
Cell Significance Index: -6.1100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1002
Cell Significance Index: -6.4700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1094
Cell Significance Index: -4.4800 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1106
Cell Significance Index: -1.8600 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: -0.1121
Cell Significance Index: -1.5400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1246
Cell Significance Index: -3.6700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1249
Cell Significance Index: -2.0900 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.1262
Cell Significance Index: -1.6300 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.1283
Cell Significance Index: -1.8000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1396
Cell Significance Index: -6.5600 - Cell Name: endothelial cell (CL0000115)
Fold Change: -0.1432
Cell Significance Index: -1.7600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1488
Cell Significance Index: -7.8100 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: -0.1573
Cell Significance Index: -1.0800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1582
Cell Significance Index: -6.8800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1616
Cell Significance Index: -9.0700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1656
Cell Significance Index: -8.6000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1677
Cell Significance Index: -7.8200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1692
Cell Significance Index: -4.3500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1708
Cell Significance Index: -5.9900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1715
Cell Significance Index: -5.9600 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1754
Cell Significance Index: -4.3800 - Cell Name: endothelial stalk cell (CL0002671)
Fold Change: -0.1803
Cell Significance Index: -2.0200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1815
Cell Significance Index: -3.8000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1873
Cell Significance Index: -5.0100 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.1874
Cell Significance Index: -3.2400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1886
Cell Significance Index: -5.2700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1931
Cell Significance Index: -8.5400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2079
Cell Significance Index: -2.9900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2092
Cell Significance Index: -6.8500 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.2094
Cell Significance Index: -4.2600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2129
Cell Significance Index: -6.7800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2141
Cell Significance Index: -6.1100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2263
Cell Significance Index: -8.5700 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: -0.2302
Cell Significance Index: -0.9900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2367
Cell Significance Index: -6.3200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2480
Cell Significance Index: -7.1100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2498
Cell Significance Index: -9.1700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2512
Cell Significance Index: -5.3700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2693
Cell Significance Index: -7.0800 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.2709
Cell Significance Index: -3.8900 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2746
Cell Significance Index: -6.8500 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.2799
Cell Significance Index: -7.1300 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: -0.2817
Cell Significance Index: -3.0600 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.2823
Cell Significance Index: -7.0500 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: -0.2888
Cell Significance Index: -2.2800 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.2896
Cell Significance Index: -4.1200 - Cell Name: endocardial cell (CL0002350)
Fold Change: -0.2913
Cell Significance Index: -1.7200 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: -0.3103
Cell Significance Index: -2.9500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.3206
Cell Significance Index: -6.3100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3217
Cell Significance Index: -6.9500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.3241
Cell Significance Index: -3.3600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3259
Cell Significance Index: -8.8700 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3313
Cell Significance Index: -6.9200 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.3336
Cell Significance Index: -4.5800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.3361
Cell Significance Index: -8.0600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3370
Cell Significance Index: -7.3800 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.3385
Cell Significance Index: -6.7500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3402
Cell Significance Index: -7.2200 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.3457
Cell Significance Index: -5.9100 - Cell Name: monocyte (CL0000576)
Fold Change: -0.3476
Cell Significance Index: -4.0000 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: -0.3486
Cell Significance Index: -3.9600 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.3530
Cell Significance Index: -4.0400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.3532
Cell Significance Index: -3.8400 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: -0.3556
Cell Significance Index: -5.3200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2653762008
Symbol: APJ_HUMAN
Name: Apelin receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8294032
Title: A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11.
PubMed ID: 8294032
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11090199
Title: Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.
PubMed ID: 11090199
PubMed ID: 25639753
Title: Elabela-apelin receptor signaling pathway is functional in mammalian systems.
PubMed ID: 25639753
DOI: 10.1038/srep08170
PubMed ID: 28137936
Title: Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension.
PubMed ID: 28137936
Sequence Information:
- Length: 380
- Mass: 42660
- Checksum: 78DB18BEA6D2B2E4
- Sequence:
MEEGGDFDNY YGADNQSECE YTDWKSSGAL IPAIYMLVFL LGTTGNGLVL WTVFRSSREK RRSADIFIAS LAVADLTFVV TLPLWATYTY RDYDWPFGTF FCKLSSYLIF VNMYASVFCL TGLSFDRYLA IVRPVANARL RLRVSGAVAT AVLWVLAALL AMPVMVLRTT GDLENTTKVQ CYMDYSMVAT VSSEWAWEVG LGVSSTTVGF VVPFTIMLTC YFFIAQTIAG HFRKERIEGL RKRRRLLSII VVLVVTFALC WMPYHLVKTL YMLGSLLHWP CDFDLFLMNI FPYCTCISYV NSCLNPFLYA FFDPRFRQAC TSMLCCGQSR CAGTSHSSSG EKSASYSSGH SQGPGPNMGK GGEQMHEKSI PYSQETLVVD
Genular Protein ID: 412901375
Symbol: B2RDH3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 380
- Mass: 42790
- Checksum: 53B6AB649B7161A9
- Sequence:
MEEGGDFDNY YGADNQSECE YTDWKSSGAL IPAIYMLVFL LGTTGNGLVL WTVFRSSREK RRSADIFIAS LAVADLTFVV TLPLWATYTY RDYDWPFGTF FCKLSSYLIF VNMYASVFCL TGLSFDRYLA IVRPVANARL RLRVSWAVAT AVLWVLAALL AMPVMVLRTT GDLENTTKVQ CYMDYSMVAT VSSEWAWEVG LGVSSTTVGF VVPFTIMLTC YFFIAQTIAG HFRKERIEGL RKRRRLLSII VVLVVTFALC WMPYHLVKTL YMLGSLLHWP CDFDLFLMNI FPYCTCISYV NSCLNPFLYA FFDPRFRQAC TSMLCCGQSR CAGTSHSSSG EKSASYSSGH SQGPGPNMGK GGEQMHEKSI PYSQETLVVD
Genular Protein ID: 1878646929
Symbol: B3KQN4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16303743
Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
PubMed ID: 16303743
Sequence Information:
- Length: 380
- Mass: 42689
- Checksum: 78D9CA6EA6D2B1E7
- Sequence:
MEEGGDFDNY YGADNQSECE YTDWKSSGAL IPAIYMLVFL LGTTGNGLVL WTVFRSSREK RRSADIFIAS LAVADLTFVV TLPLWATYTY RDYDWPFGTF FCKLSSYLIF VNMYASVFCL TGLSFDRYLA IVRPVANARL RLRVSGAVAT AVLWVLAALL AMPVMVLRTT GDLENTTKVQ CYMDYSMVAT VSSEWAWEVG LGVSSTTVGF VVPFTIMLTC YFFIAQTIAG HFRKERIEGL RKRRRLLSII VVLVVTFALC WMPYHLVKTL YMLGSLLHWP CDFDLFLMNI FPYCTCISYV NSCLNPFLYA FFDPRFRRAC TSMLCCGQSR CAGTSHSSSG EKSASYSSGH SQGPGPNMGK GGEQMHEKSI PYSQETLVVD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.