Genular: Defining Cellular Identity and Function

Details for: Pik3r3

Gene ID: 18710

Symbol: Pik3r3

Ensembl ID: ENSMUSG00000028698

Description: phosphoinositide-3-kinase regulatory subunit 3

Associated with

Adaptive immune system
(R-MMU-1280218)
Axon guidance
(R-MMU-422475)
Cd28 co-stimulation
(R-MMU-389356)
Cd28 dependent pi3k/akt signaling
(R-MMU-389357)
Costimulation by the cd28 family
(R-MMU-388841)
Cytokine signaling in immune system
(R-MMU-1280215)
Developmental biology
(R-MMU-1266738)
Esr-mediated signaling
(R-MMU-8939211)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpvi-mediated activation cascade
(R-MMU-114604)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Interleukin-2 family signaling
(R-MMU-451927)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-MMU-512988)
Interleukin-7 signaling
(R-MMU-1266695)
Interleukin receptor shc signaling
(R-MMU-912526)
Intracellular signaling by second messengers
(R-MMU-9006925)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Nervous system development
(R-MMU-9675108)
Phospholipid metabolism
(R-MMU-1483257)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pi metabolism
(R-MMU-1483255)
Pip3 activates akt signaling
(R-MMU-1257604)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Regulation of signaling by cbl
(R-MMU-912631)
Ret signaling
(R-MMU-8853659)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by gpcr
(R-MMU-372790)
Signaling by interleukins
(R-MMU-449147)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by scf-kit
(R-MMU-1433557)
Signal transduction
(R-MMU-162582)
Synthesis of pips at the plasma membrane
(R-MMU-1660499)
1-phosphatidylinositol-3-kinase regulator activity
(GO:0046935)
Cell migration involved in sprouting angiogenesis
(GO:0002042)
Insulin receptor signaling pathway
(GO:0008286)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phosphatidylinositol 3-kinase complex
(GO:0005942)
Phosphatidylinositol phosphate biosynthetic process
(GO:0046854)
Phosphotyrosine residue binding
(GO:0001784)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)

Other Information

Proteins

Phosphatidylinositol 3-kinase regulatory subunit gamma

Genular Protein ID: 3477548530

Symbol: P55G_MOUSE

Name: Phosphatidylinositol 3-kinase regulatory subunit gamma

UniProtKB Accession Codes:

Q64143

Database IDs:

Citations:

PubMed ID: 7542745

Title: The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase.

PubMed ID: 7542745

DOI: 10.1128/mcb.15.8.4453

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 461
Mass: 54474
Checksum: 97A01A0DFAAC661F
Sequence:

MYNTVWSMDR DDADWREVMM PYSTELIFYI EMDPPALPPK PPKPMTPAVT NGMKDSFISL 
QDAEWYWGDI SREEVNDKLR DMPDGTFLVR DASTKMQGDY TLTLRKGGNN KLIKIYHRDG 
KYGFSEPLTF TSVVELINHY HHESLAQYNP KLDVKLTYPV SRFQQDQLVK EDNIDAVGKN 
LQEFHSQYQE KSKEYDRLYE EYTRTSQEIQ MKRTAIEAFN ETIKIFEEQC HTQEQHSKDY 
IERFRREGNE KEIERIMMNY DKLKSRLGEI HDSKLRLEQD LKKQALDNRE IDKKMNSIKP 
DLIQLRKIRD QHLVWLNHRG VRQRRLNAWL GIKNEDSDES YFINEEDENL PHYDEKTWFV 
EDINRVQAED LLYGKPDGAF LIRESSKKGC YACSVVADGE VKHCVIYSTA RGYGFAEPYN 
LYSSLKELVL HYQQTSLVQH NDSLNVRLAY PVHAQMPTLC R

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.