Details for: Pim2

Gene ID: 18715

Symbol: Pim2

Ensembl ID: ENSMUSG00000031155

Description: proviral integration site 2

Associated with

Other Information

Genular Protein ID: 1971101407

Symbol: PIM2_MOUSE

Name: Serine/threonine-protein kinase pim-2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7781606

Title: Proviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2.

PubMed ID: 7781606

DOI: 10.1002/j.1460-2075.1995.tb07251.x

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9294606

Title: Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc.

PubMed ID: 9294606

DOI: 10.1038/sj.onc.1201288

PubMed ID: 12869584

Title: The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor.

PubMed ID: 12869584

DOI: 10.1101/gad.1105003

PubMed ID: 12954615

Title: The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.

PubMed ID: 12954615

DOI: 10.1074/jbc.m307933200

PubMed ID: 15548703

Title: Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation.

PubMed ID: 15548703

DOI: 10.1158/0008-5472.can-04-2284

PubMed ID: 15199164

Title: Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors.

PubMed ID: 15199164

DOI: 10.1128/mcb.24.13.6104-6115.2004

PubMed ID: 15705789

Title: Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.

PubMed ID: 15705789

DOI: 10.1182/blood-2004-09-3706

PubMed ID: 15642745

Title: The Pim kinases control rapamycin-resistant T cell survival and activation.

PubMed ID: 15642745

DOI: 10.1084/jem.20042020

PubMed ID: 17476689

Title: PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.

PubMed ID: 17476689

DOI: 10.1002/jcp.21117

PubMed ID: 18438430

Title: Pim kinase-dependent inhibition of c-Myc degradation.

PubMed ID: 18438430

DOI: 10.1038/onc.2008.123

Sequence Information:

  • Length: 370
  • Mass: 40060
  • Checksum: 12BB70BFD04DBE8A
  • Sequence:
  • MARATNLNAA PSAGASGPPD SLPSTLAPPS PGSPAALPRA STPCGLSGFS GLNIRSTSSM 
    LTKPLQGHPS PPVTPTQPPG GKDRAAFEAE YRLGPLLGKG GFGTVFAGHR VTDRRQVAIK 
    VISRNRVLGW STVSDSVTCP LEVALLWKVG EGNGHPGVIR LLDWFETPEG FMLVLERPMP 
    AQDLFDYITE KGPLGESCSR SFFTQVVAAV QHCHARGVVH RDIKDENILI DLCRGSIKLI 
    DFGSGALLHD EPYTDFDGTR VYSPPEWISR HQYHALPATV WSLGVLLYDM VCGDIPFERD 
    QEILEAELHF PAHVSPDCCA LIRRCLAPKP CSRPSLEEIL LDPWMQSPAE EKPINSSKGS 
    PTPLPWSLLP

Genular Protein ID: 330968222

Symbol: Q8R1Z0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 221
  • Mass: 24785
  • Checksum: 6F7BA1878CFA1BB8
  • Sequence:
  • GEGNGHPGVI RLLDWFETPE GFMLVLERPM PAQDLFDYIT EKGPLGESCS RSFFTQVVAA 
    VQHCHARGVV HRDIKDENIL IDLCRGSIKL IDFGSGALLH DEPYTDFDGT RVYSPPEWIS 
    RHQYHALPAT VWSLGVLLYD MVCGDIPFER DQEILEAELH FPAHVSPDCC ALIRRCLAPK 
    PCSRPSLEEI LLDPWMQSPA EEKPINSSKG SPTPLPWSLL P

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.