Details for: Pkia

Gene ID: 18767

Symbol: Pkia

Ensembl ID: ENSMUSG00000027499

Description: protein kinase inhibitor, alpha

Associated with

  • Camp-dependent protein kinase inhibitor activity
    (GO:0004862)
  • Cytoplasm
    (GO:0005737)
  • Negative regulation of camp-dependent protein kinase activity
    (GO:2000480)
  • Negative regulation of catalytic activity
    (GO:0043086)
  • Negative regulation of protein import into nucleus
    (GO:0042308)
  • Negative regulation of protein kinase activity
    (GO:0006469)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Protein kinase a catalytic subunit binding
    (GO:0034236)
  • Protein kinase inhibitor activity
    (GO:0004860)
  • Regulation of g2/m transition of mitotic cell cycle
    (GO:0010389)

Other Information

Genular Protein ID: 2648659653

Symbol: IPKA_MOUSE

Name: cAMP-dependent protein kinase inhibitor alpha

UniProtKB Accession Codes:

P63248 P27776 Q3UTL0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DIP 1 DNASU 1 EMBL 5 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 51 PDBsum 50 PIR 1 PIRSF 1 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 1710219

Title: Isolation and characterization of cDNA clones for an inhibitor protein of cAMP-dependent protein kinase.

PubMed ID: 1710219

DOI: 10.1016/s0021-9258(18)99142-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 8443157

Title: Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor.

PubMed ID: 8443157

DOI: 10.1021/bi00060a005

Sequence Information:

  • Length: 76
  • Mass: 7960
  • Checksum: FCCE07281498788A
  • Sequence:
    • MTDVETTYAD FIASGRTGRR NAIHDILVSS ASGNSNELAL KLAGLDINKT EGEDDGQRSS 
TEQSGEAQGE AAKSES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.