Genular: Defining Cellular Identity and Function

Details for: Plaur

Gene ID: 18793

Symbol: Plaur

Ensembl ID: ENSMUSG00000046223

Description: plasminogen activator, urokinase receptor

Associated with

Attachment of gpi anchor to upar
(R-MMU-162791)
Dissolution of fibrin clot
(R-MMU-75205)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
Post-translational modification: synthesis of gpi-anchored proteins
(R-MMU-163125)
Post-translational protein modification
(R-MMU-597592)
Cell surface
(GO:0009986)
Enzyme binding
(GO:0019899)
Epithelial cell differentiation involved in prostate gland development
(GO:0060742)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Membrane
(GO:0016020)
Mesenchymal cell differentiation
(GO:0048762)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
(GO:2001268)
Negative regulation of intrinsic apoptotic signaling pathway
(GO:2001243)
Plasma membrane
(GO:0005886)
Positive regulation of dna binding
(GO:0043388)
Positive regulation of epidermal growth factor receptor signaling pathway
(GO:0045742)
Positive regulation of homotypic cell-cell adhesion
(GO:0034112)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of release of cytochrome c from mitochondria
(GO:0090200)
Protein binding
(GO:0005515)
Protein complex involved in cell-matrix adhesion
(GO:0098637)
Protein domain specific binding
(GO:0019904)
Regulation of cell adhesion
(GO:0030155)
Regulation of fibrinolysis
(GO:0051917)
Regulation of plasminogen activation
(GO:0010755)
Serine-type endopeptidase complex
(GO:1905370)
Side of membrane
(GO:0098552)
Signaling receptor binding
(GO:0005102)
Urokinase plasminogen activator signaling pathway
(GO:0038195)

Other Information

Proteins

Urokinase plasminogen activator surface receptor

Genular Protein ID: 654361850

Symbol: UPAR_MOUSE

Name: Urokinase plasminogen activator surface receptor

UniProtKB Accession Codes:

P35456 P35457

Database IDs:

Citations:

PubMed ID: 1661735

Title: Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract.

PubMed ID: 1661735

DOI: 10.1083/jcb.115.6.1763

PubMed ID: 7929309

Title: The murine urokinase-type plasminogen activator receptor gene.

PubMed ID: 7929309

DOI: 10.1016/s0021-9258(18)47149-9

PubMed ID: 19667118

Title: Sushi repeat protein X-linked 2, a novel mediator of angiogenesis.

PubMed ID: 19667118

DOI: 10.1096/fj.09-135202

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20133942

Title: Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy.

PubMed ID: 20133942

DOI: 10.1074/jbc.m109.093492

Sequence Information:

Length: 327
Mass: 35428
Checksum: A117441D738B6343
Sequence:

MGLPRRLLLL LLLATTCVPA SQGLQCMQCE SNQSCLVEEC ALGQDLCRTT VLREWQDDRE 
LEVVTRGCAH SEKTNRTMSY RMGSMIISLT ETVCATNLCN RPRPGARGRA FPQGRYLECA 
SCTSLDQSCE RGREQSLQCR YPTEHCIEVV TLQSTERSLK DEDYTRGCGS LPGCPGTAGF 
HSNQTFHFLK CCNYTHCNGG PVLDLQSFPP NGFQCYSCEG NNTLGCSSEE ASLINCRGPM 
NQCLVATGLD VLGNRSYTVR GCATASWCQG SHVADSFPTH LNVSVSCCHG SGCNSPTGGA 
PRPGPAQLSL IASLLLTLGL WGVLLWT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Plaur

Associated with

Other Information

Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract. PubMed ID: 1661735

The murine urokinase-type plasminogen activator receptor gene. PubMed ID: 7929309

Sushi repeat protein X-linked 2, a novel mediator of angiogenesis. PubMed ID: 19667118