Genular: Defining Cellular Identity and Function

Details for: Plcd4

Gene ID: 18802

Symbol: Plcd4

Ensembl ID: ENSMUSG00000026173

Description: phospholipase C, delta 4

Associated with

Inositol phosphate metabolism
(R-MMU-1483249)
Metabolism
(R-MMU-1430728)
Synthesis of ip3 and ip4 in the cytosol
(R-MMU-1855204)
Acrosome reaction
(GO:0007340)
Calcium ion binding
(GO:0005509)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
G-protein alpha-subunit binding
(GO:0001965)
Guanyl-nucleotide exchange factor activity
(GO:0005085)
Hydrolase activity
(GO:0016787)
Intracellular anatomical structure
(GO:0005622)
Intracellular signal transduction
(GO:0035556)
Lipid catabolic process
(GO:0016042)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Nucleus
(GO:0005634)
Phosphatidylinositol metabolic process
(GO:0046488)
Phosphatidylinositol phospholipase c activity
(GO:0004435)
Phospholipase c activity
(GO:0004629)
Phosphoric diester hydrolase activity
(GO:0008081)
Plasma membrane
(GO:0005886)
Signal transduction
(GO:0007165)
Small gtpase-mediated signal transduction
(GO:0007264)

Other Information

Proteins

Phosphoinositide phospholipase C-delta-4

Genular Protein ID: 4283205691

Symbol: PLCD4_MOUSE

Name: Phosphoinositide phospholipase C-delta-4

UniProtKB Accession Codes:

Q8K3R3 Q3USN9 Q6NZF7 Q8CAB1 Q9CUC1

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10601847

Title: Growth factor-induced promoter activation of murine phospholipase C delta4 gene.

PubMed ID: 10601847

DOI: 10.1046/j.1432-1327.2000.00943.x

PubMed ID: 11340203

Title: Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction.

PubMed ID: 11340203

DOI: 10.1126/science.1059042

PubMed ID: 12695499

Title: Phospholipase Cdelta4 is required for Ca2+ mobilization essential for acrosome reaction in sperm.

PubMed ID: 12695499

DOI: 10.1083/jcb.200210057

PubMed ID: 16272139

Title: Phospholipase Cdelta4 associates with glutamate receptor interacting protein 1 in testis.

PubMed ID: 16272139

DOI: 10.1093/jb/mvi135

PubMed ID: 16998201

Title: Disruption of phospholipase Cdelta4 gene modulates the liver regeneration in cooperation with nuclear protein kinase C.

PubMed ID: 16998201

DOI: 10.1093/jb/mvj194

Sequence Information:

Length: 807
Mass: 92694
Checksum: C109F6255CED45F7
Sequence:

MTSQIQDLLA TDQDLLLMQE GTMMRKVRTK SWKKLRYFRL QNDGMTVWHG SQPESMPKPT 
FSISDVERIR KGQDSELLRY LVEEFPLEQG FTVVFHGRRP NLDLVANSVE EAQIWMRGLQ 
LLVDLVASMD HQEQMDQMLN EWFQQADRNQ DGRMSFREAQ RLLLLMNVEM DEEYAFSLFQ 
EADVTQSDDL GSEEFVQFYK ALTKRTEIEE IFEDFSSDKQ KLTLLEFVDF LRKEQKEKDH 
APDLALELID RYEPSENGRL LHVLSKDGFL KYLCSKDGNI FNSDCLPIYQ DMTQPLSHYY 
INSSHNTYLV GDQLCGQSSV EGYIRALKRG CRCVEVDTWD GPDGEPVVYH GHTLTSRILF 
KDVLATLAQY AFQSSDYPLI LSLENHCTWE QQRTMAHHLT EILGEQLLRN TLEGLLVDSM 
PSPEQLRGKI LVKGKKLRTI EVDKEEEEEE EEEELEKDEG PDLDPASPEL DTQPQPETQG 
QAAGNKKERK KKVMKCPMSC LLICGHVMAQ APSSIPESIL LSKQFLLLSS TTIMCPDLSA 
LVVYLRTVPF CSFTHSKENY HIYDISSFSE SKAKNLIKEA GNEFVQHNAR QLCRVYPSGL 
RTDSSNFNPQ EHWNVGCQMV AMNMQTAGSA MDICDGLFRQ NGGSGYVLKP EFLRDTQSSF 
NPERPISLYK AQILVVQVIS GQQLPKVDKT KETTVVDPLV KVELYGVPED TKEQETSHVE 
NNGINPYWGE TFYFRLQVPE LAMLRFVVKD YSRKSRNNFI GQYTLPWTCM KQGYRHVSLL 
SRDGTSLNPA SIFVYTCMQE DLDMDEP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Plcd4

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Growth factor-induced promoter activation of murine phospholipase C delta4 gene. PubMed ID: 10601847

Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction. PubMed ID: 11340203

Phospholipase Cdelta4 is required for Ca2+ mobilization essential for acrosome reaction in sperm. PubMed ID: 12695499

Phospholipase Cdelta4 associates with glutamate receptor interacting protein 1 in testis. PubMed ID: 16272139

Disruption of phospholipase Cdelta4 gene modulates the liver regeneration in cooperation with nuclear protein kinase C. PubMed ID: 16998201