Details for: Plcg1
Associated with
Other Information
Genular Protein ID: 1371053471
Symbol: PLCG1_MOUSE
Name: Phosphoinositide phospholipase C-gamma-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8687404
Title: Phospholipase C in mouse oocytes: characterization of beta and gamma isoforms and their possible involvement in sperm-induced Ca2+ spiking.
PubMed ID: 8687404
DOI: 10.1042/bj3160583
PubMed ID: 1714377
Title: Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.
PubMed ID: 1714377
PubMed ID: 1646396
Title: Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction.
PubMed ID: 1646396
PubMed ID: 8943348
Title: Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.
PubMed ID: 8943348
PubMed ID: 9299537
Title: The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma.
PubMed ID: 9299537
PubMed ID: 10748127
Title: Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains.
PubMed ID: 10748127
PubMed ID: 10646608
Title: Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.
PubMed ID: 10646608
DOI: 10.1038/35003228
PubMed ID: 11463797
Title: MIST functions through distinct domains in immunoreceptor signaling in the presence and absence of LAT.
PubMed ID: 11463797
PubMed ID: 12367511
Title: Mechanism of TrkB-mediated hippocampal long-term potentiation.
PubMed ID: 12367511
PubMed ID: 15308098
Title: Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.
PubMed ID: 15308098
PubMed ID: 15629145
Title: Tyrosine 769 of the keratinocyte growth factor receptor is required for receptor signaling but not endocytosis.
PubMed ID: 15629145
PubMed ID: 16000869
Title: Inositol 5'-phosphatase, SHIP1 interacts with phospholipase C-gamma1 and modulates EGF-induced PLC activity.
PubMed ID: 16000869
DOI: 10.1038/emm.2005.22
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 17620338
Title: Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.
PubMed ID: 17620338
PubMed ID: 17635937
Title: Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration.
PubMed ID: 17635937
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 18034455
Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
PubMed ID: 18034455
DOI: 10.1021/pr0701254
PubMed ID: 19597499
Title: Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.
PubMed ID: 19597499
DOI: 10.1038/ni.1766
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 22561606
Title: Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling.
PubMed ID: 22561606
DOI: 10.1038/ni.2301
PubMed ID: 21262971
Title: Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.
PubMed ID: 21262971
Sequence Information:
- Length: 1302
- Mass: 149668
- Checksum: 5D123C508D425EB2
- Sequence:
MAGVATPCAN GCGPGAPSEA EVLHLCRSLE VGTVMTLFYS KKSQRPERKT FQVKLETRQI TWSRGADKIE GSIDIREIKE IRPGKTSRDF DRYQEDPAFR PDQSHCFVIL YGMEFRLKTL SLQATSEDEV NMWIKGLTWL MEDTLQAATP LQIERWLRKQ FYSVDRNRED RISAKDLKNM LSQVNYRVPN MRFLRERLTD LEQRSGDITY GQFAQLYRSL MYSAQKTMDL PFLETNALRT GERPEHCQVS LSEFQQFLLE YQGELWAVDR LQVQEFMLSF LRDPLREIEE PYFFLDELVT FLFSKENSVW NSQLDAVCPD TMNNPLSHYW ISSSHNTYLT GDQFSSESSL EAYARCLRMG CRCIELDCWD GPDGMPVIYH GHTLTTKIKF SDVLHTIKEH AFVASEYPVI LSIEDHCSIA QQRNMAQHFR KVLGDTLLTK PVDIAADGLP SPNQLRRKIL IKHKKLAEGS AYEEVPTSVM YSENDISNSI KNGILYLEDP VNHEWYPHYF VLTSSKIYYS EETSSDQGNE DEEEPKEASS STELHSSEKW FHGKLGAGRD GRHIAERLLT EYCIETGAPD GSFLVRESET FVGDYTLSFW RNGKVQHCRI HSRQDAGTPK FFLTDNLVFD SLYDLITHYQ QVPLRCNEFE MRLSEPVPQT NAHESKEWYH ASLTRAQAEH MLMRVPRDGA FLVRKRNEPN SYAISFRAEG KIKHCRVQQE GQTVMLGNSE FDSLVDLISY YEKHPLYRKM KLRYPINEEA LEKIGTAEPD YGALYEGRNP GFYVEANPMP TFKCAVKALF DYKAQREDEL TFTKSAIIQN VEKQDGGWWR GDYGGKKQLW FPSNYVEEMI NPAVLEPERE HLDENSPLGD LLRGVLDVPA CQIAIRPEGK NNRLFVFSIS MPSVAQWSLD VAADSQEELQ DWVKKIREVA QTADARLTEG KMMERRKKIA LELSELVVYC RPVPFDEEKI GTERACYRDM SSFPETKAEK YVNKAKGKKF LQYNRLQLSR IYPKGQRLDS SNYDPLPMWI CGSQLVALNF QTPDKPMQMN QALFMAGGHC GYVLQPSTMR DEAFDPFDKS SLRGLEPCVI CIEVLGARHL PKNGRGIVCP FVEIEVAGAE YDSTKQKTEF VVDNGLNPVW PAKPFHFQIS NPEFAFLRFV VYEEDMFSDQ NFLAQATFPV KGLKTGYRAV PLKNNYSEDL ELASLLIKID IFPAKENGDL SPFSGISLRE RASDASSQLF HVRAREGSFE ARYQQPFEDF RISQEHLADH FDSRERSTSD GPSSATNLIE DPLHDKLWKC SL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.