Details for: Plp1

Gene ID: 18823

Symbol: Plp1

Ensembl ID: ENSMUSG00000031425

Description: proteolipid protein (myelin) 1

Associated with

Other Information

Genular Protein ID: 3834592447

Symbol: MYPR_MOUSE

Name: Myelin proteolipid protein

UniProtKB Accession Codes:

P60202 P04400 P06905 Q9WUS9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 21 Ensembl 2 ExpressionAtlas 1 GO 18 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 6 SMART 1 SMR 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 2 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 3469678

Title: Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse.

PubMed ID: 3469678

DOI: 10.1073/pnas.84.5.1454

PubMed ID: 2451027

Title: Myelin proteolipid protein gene structure and its regulation of expression in normal and jimpy mutant mice.

PubMed ID: 2451027

DOI: 10.1016/0022-2836(88)90303-8

PubMed ID: 2449535

Title: Structure and expression of the mouse myelin proteolipid protein gene.

PubMed ID: 2449535

DOI: 10.1002/jnr.490180302

PubMed ID: 3466187

Title: Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

PubMed ID: 3466187

DOI: 10.1073/pnas.83.23.9264

PubMed ID: 2441390

Title: Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

PubMed ID: 2441390

DOI: 10.1073/pnas.84.16.5665

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2442307

Title: Developmental expression of the myelin proteolipid protein and basic protein mRNAs in normal and dysmyelinating mutant mice.

PubMed ID: 2442307

DOI: 10.1111/j.1471-4159.1987.tb10005.x

PubMed ID: 2432393

Title: Characterization of myelin proteolipid mRNAs in normal and jimpy mice.

PubMed ID: 2432393

DOI: 10.1128/mcb.6.11.3755-3762.1986

PubMed ID: 2444462

Title: An AG to a GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon.

PubMed ID: 2444462

DOI: 10.1016/0014-5793(87)80331-9

PubMed ID: 17634366

Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.

PubMed ID: 17634366

DOI: 10.1523/jneurosci.1254-07.2007

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 1688931

Title: Conservative amino acid substitution in the myelin proteolipid protein of jimpymsd mice.

PubMed ID: 1688931

DOI: 10.1523/jneurosci.10-01-00117.1990

PubMed ID: 1380672

Title: Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene.

PubMed ID: 1380672

DOI: 10.1038/358758a0

Sequence Information:

  • Length: 277
  • Mass: 30077
  • Checksum: 3C2BC973C3061C38
  • Sequence:
    • MGLLECCARC LVGAPFASLV ATGLCFFGVA LFCGCGHEAL TGTEKLIETY FSKNYQDYEY 
LINVIHAFQY VIYGTASFFF LYGALLLAEG FYTTGAVRQI FGDYKTTICG KGLSATVTGG 
QKGRGSRGQH QAHSLERVCH CLGKWLGHPD KFVGITYALT VVWLLVFACS AVPVYIYFNT 
WTTCQSIAFP SKTSASIGSL CADARMYGVL PWNAFPGKVC GSNLLSICKT AEFQMTFHLF 
IAAFVGAAAT LVSLLTFMIA ATYNFAVLKL MGRGTKF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.