Pmp22 | ENSMUSG00000018217 | NCBI 18858

Details for: Pmp22

Gene ID: 18858

Symbol: Pmp22

Ensembl ID: ENSMUSG00000018217

Description: peripheral myelin protein 22

Associated with

Actin cytoskeleton organization
(GO:0030036)
Adult locomotory behavior
(GO:0008344)
Adult walking behavior
(GO:0007628)
Aggresome assembly
(GO:0070842)
Apoptotic process
(GO:0006915)
Autophagy
(GO:0006914)
Axon development
(GO:0061564)
Basement membrane organization
(GO:0071711)
Bicellular tight junction
(GO:0005923)
Bleb assembly
(GO:0032060)
Cell adhesion
(GO:0007155)
Cell cycle
(GO:0007049)
Cell differentiation
(GO:0030154)
Cell surface
(GO:0009986)
Cellular lipid metabolic process
(GO:0044255)
Cellular localization
(GO:0051641)
Cellular response to heat
(GO:0034605)
Cellular response to unfolded protein
(GO:0034620)
Cholesterol metabolic process
(GO:0008203)
Compact myelin
(GO:0043218)
Cytoskeletal motor activity
(GO:0003774)
Fibroblast migration
(GO:0010761)
Gliogenesis
(GO:0042063)
Immune response
(GO:0006955)
Integrin complex
(GO:0008305)
Lamellipodium assembly
(GO:0030032)
Laminin complex
(GO:0043256)
Mating
(GO:0007618)
Membrane
(GO:0016020)
Membrane raft organization
(GO:0031579)
Motor behavior
(GO:0061744)
Multicellular organism growth
(GO:0035264)
Muscle cell development
(GO:0055001)
Myelin assembly
(GO:0032288)
Myelination
(GO:0042552)
Myelination in peripheral nervous system
(GO:0022011)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of neuron projection development
(GO:0010977)
Neuromuscular junction development, skeletal muscle fiber
(GO:0098529)
Neuromuscular process
(GO:0050905)
Neuronal action potential
(GO:0019228)
Neuronal action potential propagation
(GO:0019227)
Neuronal ion channel clustering
(GO:0045161)
Paranodal junction assembly
(GO:0030913)
Perinuclear region of cytoplasm
(GO:0048471)
Peripheral nervous system development
(GO:0007422)
Peripheral nervous system neuron axonogenesis
(GO:0048936)
Plasma membrane
(GO:0005886)
Positive regulation of gene expression
(GO:0010628)
Proteasomal protein catabolic process
(GO:0010498)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Regulation of apoptotic signaling pathway
(GO:2001233)
Regulation of cell cycle
(GO:0051726)
Regulation of gene expression
(GO:0010468)
Regulation of glial cell apoptotic process
(GO:0034350)
Regulation of inflammatory response
(GO:0050727)
Regulation of protein serine/threonine kinase activity
(GO:0071900)
Regulation of schwann cell proliferation
(GO:0010624)
Response to bacterium
(GO:0009617)
Response to endoplasmic reticulum stress
(GO:0034976)
Schwann cell development
(GO:0014044)
Schwann cell differentiation
(GO:0014037)
Schwann cell migration
(GO:0036135)
Striated muscle cell differentiation
(GO:0051146)
Transmission of nerve impulse
(GO:0019226)
Vestibular reflex
(GO:0060005)

Other Information

Proteins

Peripheral myelin protein 22
Q5SXS3_MOUSE

Genular Protein ID: 4038687344

Symbol: PMP22_MOUSE

Name: Peripheral myelin protein 22

UniProtKB Accession Codes:

P16646 Q91XF9

Database IDs:

Citations:

PubMed ID: 1692961

Title: A growth arrest-specific (gas) gene codes for a membrane protein.

PubMed ID: 1692961

DOI: 10.1128/mcb.10.6.2924-2930.1990

PubMed ID: 1552943

Title: Trembler mouse carries a point mutation in a myelin gene.

PubMed ID: 1552943

DOI: 10.1038/356241a0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 30773261

Title: Loss of Emp2 compromises cardiogenic differentiation in mouse embryonic stem cells.

PubMed ID: 30773261

DOI: 10.1016/j.bbrc.2019.02.048

PubMed ID: 35178836

Title: DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression.

PubMed ID: 35178836

DOI: 10.1111/cas.15300

PubMed ID: 1374899

Title: A leucine-to-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse.

PubMed ID: 1374899

DOI: 10.1073/pnas.89.10.4382

Sequence Information:

Length: 161
Mass: 18023
Checksum: F9A918E6E6817118
Sequence:

MLLLLLGILF LHIAVLVLLF VSTIVSQWLV GNGHTTDLWQ NCTTSALGAV QHCYSSSVSE 
WLQSVQATMI LSVIFSVLAL FLFFCQLFTL TKGGRFYITG FFQILAGLCV MSAAAIYTVR 
HSEWHVNTDY SYGFAYILAW VAFPLALLSG IIYVILRKRE L

Genular Protein ID: 3088128826

Symbol: Q5SXS3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q5SXS3

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 160
Mass: 17910
Checksum: 9918E6E6817118F5
Sequence:

MLLLLLGILF LHIAVLVLLF VSTIVSQWLV GNGHTTDLWQ NCTTSALGAV QHCYSSSVSE 
WLQSVQATMI LSVIFSVLAL FLFFCQLFTL TKGGRFYITG FFQILAGLCV MSAAAIYTVR 
HSEWHVNTDY SYGFAYILAW VAFPLALLSG IIYVILRKRE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pmp22

Associated with

Other Information

A growth arrest-specific (gas) gene codes for a membrane protein. PubMed ID: 1692961

Trembler mouse carries a point mutation in a myelin gene. PubMed ID: 1552943

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Loss of Emp2 compromises cardiogenic differentiation in mouse embryonic stem cells. PubMed ID: 30773261

DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression. PubMed ID: 35178836

A leucine-to-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse. PubMed ID: 1374899

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303