Genular: Defining Cellular Identity and Function

Details for: Pms2

Gene ID: 18861

Symbol: Pms2

Ensembl ID: ENSMUSG00000075569

Description: PMS1 homolog2, mismatch repair system component

Associated with

Atp-dependent dna damage sensor activity
(GO:0140664)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cytosol
(GO:0005829)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Endonuclease activity
(GO:0004519)
Hydrolase activity
(GO:0016787)
Meiotic cell cycle
(GO:0051321)
Mismatched dna binding
(GO:0030983)
Mismatch repair
(GO:0006298)
Mismatch repair complex
(GO:0032300)
Mutlalpha complex
(GO:0032389)
Mutsalpha complex binding
(GO:0032407)
Nuclease activity
(GO:0004518)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Positive regulation of isotype switching to iga isotypes
(GO:0048298)
Positive regulation of isotype switching to igg isotypes
(GO:0048304)
Single-stranded dna binding
(GO:0003697)
Single base insertion or deletion binding
(GO:0032138)
Somatic hypermutation of immunoglobulin genes
(GO:0016446)
Somatic recombination of immunoglobulin gene segments
(GO:0016447)

Other Information

Proteins

DNA mismatch repair protein PMS2

Genular Protein ID: 2603899397

Symbol: PMS2_MOUSE

Name: DNA mismatch repair protein PMS2

UniProtKB Accession Codes:

P54279 B9EJ22

Database IDs:

Citations:

PubMed ID: 7628019

Title: Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis.

PubMed ID: 7628019

DOI: 10.1016/0092-8674(95)90318-6

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 859
Mass: 95298
Checksum: C544B719A1B4BB03
Sequence:

MEQTEGVSTE CAKAIKPIDG KSVHQICSGQ VVLSLSTAVK ELIENSVDAG ATTIDLRLKD 
YGVDLIEVSD NGCGVEEENF EGLALKHHTS KIQEFADLTQ VETFGFRGEA LSSLCALSDV 
TISTCHGSAS VGTRLVFDHN GKITQKTPYP RPKGTTVSVQ HLFYTLPVRY KEFQRNIKKE 
YAKMVQVLQA YCIISAGVRV SCTNQLGQGK RQPVVCTSGS SGMKENIGSV FGQKQLQSLI 
PFVQLPPSDA VCEEYGLSTS RTPQNLFYVS GFISQCTHGA GRSATDRQFF FINQRPCDPA 
KVSKLVNEVY HMYNRHQYPF VVLNVSVDSE CVDINVTPDK RQILLQEEKL LLAVLKTSLI 
GMFDSDANKL NVNQQPLLDV EGNLVKLHTA ELEKPVPGKQ DNSPSLKSTA DEKRVASISR 
LREAFSLHPT KEIKSRGPET AELTRSFPSE KRGVLSSYPS DVISYRGLRG SQDKLVSPTD 
SPGDCMDREK IEKDSGLSST SAGSEEGFST PEVASSFSSD YNVSSPEDRP SQETINCGDL 
DCRPPGTGQS LKPEDHGYQC KALPLARLSP TNAKRFKTEE RPSNVNISQR LPGPQSTSAA 
EVDVAIKMNK RIVLLEFSLS SLAKRMKQLQ HLKAQNKHEL SYRKFRAKIC PGENQAAEDE 
LRKEISKSMF AEMEILGQFN LGFIVTKLKE DLFLVDQHAA DEKYNFEMLQ QHTVLQAQRL 
ITPQTLNLTA VNEAVLIENL EIFRKNGFDF VIDEDAPVTE RAKLISLPTS KNWTFGPQDI 
DELIFMLSDS PGVMCRPSRV RQMFASRACR KSVMIGTALN ASEMKKLITH MGEMDHPWNC 
PHGRPTMRHV ANLDVISQN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.