Genular: Defining Cellular Identity and Function

Details for: Pnmt

Gene ID: 18948

Symbol: Pnmt

Ensembl ID: ENSMUSG00000038216

Description: phenylethanolamine-N-methyltransferase

Associated with

Catecholamine biosynthesis
(R-MMU-209905)
Metabolism
(R-MMU-1430728)
Metabolism of amine-derived hormones
(R-MMU-209776)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Axon
(GO:0030424)
Catecholamine biosynthetic process
(GO:0042423)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Epinephrine biosynthetic process
(GO:0042418)
Methylation
(GO:0032259)
Methyltransferase activity
(GO:0008168)
Neuronal cell body
(GO:0043025)
Norepinephrine metabolic process
(GO:0042415)
Perikaryon
(GO:0043204)
Phenylethanolamine n-methyltransferase activity
(GO:0004603)
S-adenosylmethionine-dependent methyltransferase activity
(GO:0008757)
Terminal bouton
(GO:0043195)
Transferase activity
(GO:0016740)
Varicosity
(GO:0043196)

Other Information

Proteins

Phenylethanolamine N-methyltransferase

Genular Protein ID: 1279253853

Symbol: PNMT_MOUSE

Name: Phenylethanolamine N-methyltransferase

UniProtKB Accession Codes:

P40935

Database IDs:

Citations:

PubMed ID: 8000434

Title: Visualization and ablation of phenylethanolamine N-methyltransferase producing cells in transgenic mice.

PubMed ID: 8000434

DOI: 10.1007/bf01976770

PubMed ID: 1320721

Title: Organization and complete nucleotide sequence of the gene encoding mouse phenylethanolamine N-methyltransferase.

PubMed ID: 1320721

DOI: 10.1016/0169-328x(92)90214-v

PubMed ID: 17698731

Title: Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse.

PubMed ID: 17698731

DOI: 10.1161/circulationaha.107.696005

Sequence Information:

Length: 295
Mass: 32544
Checksum: ED392D6D2244069A
Sequence:

MNGGSDLKHA TGSGSDPKHA AEMDPDSDAG QVAVALAYQR FEPRAYLRNN YAPPRGDLSN 
PDGVGPWKLR CMAQVFATGE VSGRVLIDIG SGPTIYQLLS ACAHFEDITM TDFLEVNRQE 
LGLWLREEPG AFDWSVYSQH ACLIEDKGES WQEKERQLRA RVKRVLPIDV HKPQPLGTPS 
LVPLPADALV SAFCLEAVSP DLTSFQRALH HITTLLRPGG HLLLIGALEE SWYLAGEARL 
SVVPVSEEEV REALVLGGYE VRELRTYIMP AHLCTGVDDV KGIFFAWAQK MEVQV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.