Genular: Defining Cellular Identity and Function

Details for: Pole2

Gene ID: 18974

Symbol: Pole2

Ensembl ID: ENSMUSG00000020974

Description: polymerase (DNA directed), epsilon 2 (p59 subunit)

Associated with

Activation of the pre-replicative complex
(R-MMU-68962)
Base excision repair
(R-MMU-73884)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Dna damage bypass
(R-MMU-73893)
Dna double-strand break repair
(R-MMU-5693532)
Dna repair
(R-MMU-73894)
Dna replication initiation
(R-MMU-68952)
Dna replication pre-initiation
(R-MMU-69002)
Dual incision in gg-ner
(R-MMU-5696400)
Dual incision in tc-ner
(R-MMU-6782135)
G1/s transition
(R-MMU-69206)
Gap-filling dna repair synthesis and ligation in gg-ner
(R-MMU-5696397)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-MMU-6782210)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Hdr through homologous recombination (hrr)
(R-MMU-5685942)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Homology directed repair
(R-MMU-5693538)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Nucleotide excision repair
(R-MMU-5696398)
Pcna-dependent long patch base excision repair
(R-MMU-5651801)
Recognition of dna damage by pcna-containing replication complex
(R-MMU-110314)
Resolution of abasic sites (ap sites)
(R-MMU-73933)
Resolution of ap sites via the multiple-nucleotide patch replacement pathway
(R-MMU-110373)
S phase
(R-MMU-69242)
Synthesis of dna
(R-MMU-69239)
Termination of translesion dna synthesis
(R-MMU-5656169)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-MMU-6781827)
Translesion synthesis by y family dna polymerases bypasses lesions on dna template
(R-MMU-110313)
Dna-templated dna replication
(GO:0006261)
Dna binding
(GO:0003677)
Dna replication
(GO:0006260)
Epsilon dna polymerase complex
(GO:0008622)
Error-prone translesion synthesis
(GO:0042276)
Intracellular membrane-bounded organelle
(GO:0043231)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)

Other Information

Proteins

DNA polymerase epsilon subunit 2

Genular Protein ID: 2514375355

Symbol: DPOE2_MOUSE

Name: DNA polymerase epsilon subunit 2

UniProtKB Accession Codes:

O54956 Q6P3Y7 Q8BP72

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9443964

Title: The small subunits of human and mouse DNA polymerase epsilon are homologous to the second largest subunit of the yeast Saccharomyces cerevisiae DNA polymerase epsilon.

PubMed ID: 9443964

DOI: 10.1093/nar/26.3.730

Sequence Information:

Length: 527
Mass: 59387
Checksum: 82940B0FD1584350
Sequence:

MAPERLRSRT VSAFKLRGLL LRSEATKYLT EALQSVTELE LEENLGKIID AVEKQPLSSN 
MIERSVVEAA VQECSQSMDE TIEHVFNIIG AFDIPRFIYN SERKKFLPLS MTNHAAPTLF 
GTARDKAELY LERYTILHQR THRHELFTPP VIGSHLEESG SKFQLKTIET LLGSTSKVGD 
VIVLGMITQL KEGKFFLEDP TGTVQLDLSK AQFHSGLYTE ACFVLAEGWF EDQVFHANAF 
GFPPTEPSST TRAYYGNINF FGGPSNASVK TYTKLRQLED ENKDAMFVIV SDVWLDQVQV 
LEKFHVMFSG YSPAPPTCFI LCGNFSSAPY GKNQVQALKD SLKSLADIIC EYPSIHQSSR 
FVFVPGPEDP GFGSILPRPP LAESITQEFR QRVPFSVFTT NPCRIQYCTQ EIIIFREDLV 
NKMCRNCVRF PSSSLDIPTH FVKTILSQGH LAPLPLYVCP VHWAYDYTLR VYPVPDLLVI 
ADKYDPFTVT NTDCLCINPG SFPRSGFAFK VFYPSSKTVE DSKLQGF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.