Genular: Defining Cellular Identity and Function

Details for: Pon1

Gene ID: 18979

Symbol: Pon1

Ensembl ID: ENSMUSG00000002588

Description: paraoxonase 1

Associated with

Arachidonic acid metabolism
(R-MMU-2142753)
Atorvastatin adme
(R-MMU-9754706)
Drug adme
(R-MMU-9748784)
Fatty acid metabolism
(R-MMU-8978868)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Synthesis of 5-eicosatetraenoic acids
(R-MMU-2142688)
Acyl-l-homoserine-lactone lactonohydrolase activity
(GO:0102007)
Aromatic compound catabolic process
(GO:0019439)
Aryldialkylphosphatase activity
(GO:0004063)
Arylesterase activity
(GO:0004064)
Blood circulation
(GO:0008015)
Calcium ion binding
(GO:0005509)
Carboxylic acid catabolic process
(GO:0046395)
Cholesterol metabolic process
(GO:0008203)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
High-density lipoprotein particle
(GO:0034364)
High-density lipoprotein particle binding
(GO:0008035)
Hydrolase activity
(GO:0016787)
Metal ion binding
(GO:0046872)
Organophosphate catabolic process
(GO:0046434)
Phosphatidylcholine metabolic process
(GO:0046470)
Phospholipid binding
(GO:0005543)
Positive regulation of binding
(GO:0051099)
Positive regulation of cholesterol efflux
(GO:0010875)
Positive regulation of transporter activity
(GO:0032411)
Protein homodimerization activity
(GO:0042803)
Response to fluoride
(GO:1902617)
Response to toxic substance
(GO:0009636)
Spherical high-density lipoprotein particle
(GO:0034366)

Other Information

Proteins

Serum paraoxonase/arylesterase 1

Genular Protein ID: 2034651968

Symbol: PON1_MOUSE

Name: Serum paraoxonase/arylesterase 1

UniProtKB Accession Codes:

P52430 Q91X30

Database IDs:

Citations:

PubMed ID: 7638166

Title: Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase.

PubMed ID: 7638166

DOI: 10.1073/pnas.92.16.7187

PubMed ID: 8601628

Title: Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model.

PubMed ID: 8601628

DOI: 10.1172/jci118589

PubMed ID: 9170151

Title: Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression.

PubMed ID: 9170151

DOI: 10.1097/00008571-199704000-00007

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15963993

Title: Quorum quenching enzyme activity is widely conserved in the sera of mammalian species.

PubMed ID: 15963993

DOI: 10.1016/j.febslet.2005.05.060

PubMed ID: 17330941

Title: Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.

PubMed ID: 17330941

DOI: 10.1021/pr0604559

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 355
Mass: 39565
Checksum: FFA0A71445BB80B4
Sequence:

MAKLLALTLV GLVLALYKNH RSSYQTRLNA FREVTPVELP NCNLVKGIET GAEDLEILPN 
GLTFFSTGLK YPGIKSFDPS KPGKILLMDL NKKEPAVSEL EIIGNTLDIS SFNPHGISTF 
TDEDNTVYLL VVNHPDSSST VEVFKFQEEE RSLLHLKTIT HELLPSINDI AAIGPESFYA 
TNDHYFADPY LRSWEMYLGL SWSNVVYYSP DKVQVVAEGF DFANGIGISL DGKYVYIAEL 
LAHKIHVYEK HANWTLTPLK VLNFDTLVDN ISVDPVTGDL WVGCHPNGMR IFFYDAENPP 
GSEVLRIQNI LSEDPKITVV YAENGTVLQG TTVASVYKGK LLIGTVFHKA LYCDL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pon1

Associated with

Other Information

Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase. PubMed ID: 7638166

Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model. PubMed ID: 8601628

Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression. PubMed ID: 9170151

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Quorum quenching enzyme activity is widely conserved in the sera of mammalian species. PubMed ID: 15963993

Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. PubMed ID: 17330941

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079