Details for: Pou2f2

Gene ID: 18987

Symbol: Pou2f2

Ensembl ID: ENSMUSG00000008496

Description: POU domain, class 2, transcription factor 2

Associated with

  • Gene expression (transcription)
    (R-MMU-74160)
  • Rna polymerase ii transcribes snrna genes
    (R-MMU-6807505)
  • Rna polymerase ii transcription
    (R-MMU-73857)
  • Cell maturation
    (GO:0048469)
  • Cellular response to virus
    (GO:0098586)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Immunoglobulin production
    (GO:0002377)
  • Immunoglobulin production involved in immunoglobulin-mediated immune response
    (GO:0002381)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Mature b cell differentiation
    (GO:0002335)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein domain specific binding
    (GO:0019904)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Spermidine transmembrane transporter activity
    (GO:0015606)
  • Spermidine transport
    (GO:0015848)
  • Transcription cis-regulatory region binding
    (GO:0000976)

Other Information

Genular Protein ID: 3797363712

Symbol: PO2F2_MOUSE

Name: Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2

UniProtKB Accession Codes:

Q00196 Q00197 Q00198 Q00199 Q00200 Q00201 Q05882 Q3KR47 Q3U127 Q5XML1 Q5XML2 Q61995 Q61996 Q64245

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 4 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 18 Ensembl 7 ExpressionAtlas 1 GO 23 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 7 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 4 PRINTS 2 PRO 1 PROSITE 5 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 7 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1976089

Title: Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene.

PubMed ID: 1976089

DOI: 10.1242/dev.109.2.349

PubMed ID: 2011512

Title: Multiple Oct2 isoforms are generated by alternative splicing.

PubMed ID: 2011512

DOI: 10.1093/nar/19.1.43

PubMed ID: 17285328

Title: Expression of the Oct-2 transcription factor in mouse mammary gland and cloning and characterization of a novel Oct-2 isoform.

PubMed ID: 17285328

DOI: 10.1007/s00441-006-0368-0

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7888080

Title: Short introns interrupting the Oct-2 POU domain may prevent recombination between POU family genes without interfering with potential POU domain 'shuffling' in evolution.

PubMed ID: 7888080

DOI: 10.1515/bchm3.1994.375.10.675

PubMed ID: 1970171

Title: Cloning and sequencing of POU-boxes expressed in mouse testis.

PubMed ID: 1970171

DOI: 10.1093/nar/18.6.1634

PubMed ID: 1425197

Title: Interaction of Oct-binding transcription factors with a large series of 'noncanonical' oct-sequences. Primary sequence of murine Oct-2B cDNA.

PubMed ID: 1425197

PubMed ID: 1281152

Title: Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters.

PubMed ID: 1281152

DOI: 10.1016/s0021-9258(19)73991-x

PubMed ID: 1550677

Title: Mini-Oct and Oct-2c: two novel, functionally diverse murine Oct-2 gene products are differentially expressed in the CNS.

PubMed ID: 1550677

DOI: 10.1016/0896-6273(92)90282-i

PubMed ID: 7935477

Title: Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein.

PubMed ID: 7935477

DOI: 10.1128/mcb.14.11.7633-7642.1994

PubMed ID: 23045607

Title: B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1.

PubMed ID: 23045607

DOI: 10.1084/jem.20111504

Sequence Information:

  • Length: 463
  • Mass: 49439
  • Checksum: B6669B5885ABD789
  • Sequence:
    • MVHSSMGAPE IRMSKPLEAE KQSLDSPSEH TDTERNGPDI NHQNPQNKAS PFSVSPTGPS 
TKIKAEDPSG DSAPAAPPPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL 
QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQPPK CLEPPSHPEE 
PSDLEELEQF ARTFKQRRIK LGFTQGDVGL AMGKLYGNDF SQTTISRFEA LNLSFKNMCK 
LKPLLEKWLN DAETMSVDSS LPSPNQLSSP SLGFDGLPGR RRKKRTSIET NVRFALEKSF 
LANQKPTSEE ILLIAEQLHM EKEVIRVWFC NRRQKEKRIN PCSAAPMLPS PGKPTSYSPH 
LVTPQGGAGT LPLSQASSSL STTVTTLSSA VGTLHPSRTA GGGGGGGGAA PPLNSIPSVT 
PPPPATTNST NPSPQGSHSA IGLSGLNPSA GPGLWWNPAP YQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.