Genular: Defining Cellular Identity and Function

Details for: Pou3f2

Gene ID: 18992

Symbol: Pou3f2

Ensembl ID: ENSMUSG00000095139

Description: POU domain, class 3, transcription factor 2

Associated with

Brain development
(GO:0007420)
Cell differentiation
(GO:0030154)
Cellular response to organic substance
(GO:0071310)
Cerebral cortex radially oriented cell migration
(GO:0021799)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Epidermis development
(GO:0008544)
Forebrain astrocyte development
(GO:0021897)
Forebrain ventricular zone progenitor cell division
(GO:0021869)
Hmg box domain binding
(GO:0071837)
Hypothalamus cell differentiation
(GO:0021979)
Identical protein binding
(GO:0042802)
Myelination in peripheral nervous system
(GO:0022011)
Negative regulation of gene expression
(GO:0010629)
Nervous system development
(GO:0007399)
Neuroendocrine cell differentiation
(GO:0061101)
Neurohypophysis development
(GO:0021985)
Neuron development
(GO:0048666)
Neuron differentiation
(GO:0030182)
Neuron fate commitment
(GO:0048663)
Neuron fate specification
(GO:0048665)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of multicellular organism growth
(GO:0040018)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of axonogenesis
(GO:0050770)
Regulation of cell differentiation
(GO:0045595)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Schwann cell development
(GO:0014044)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

POU domain, class 3, transcription factor 2

Genular Protein ID: 3480049619

Symbol: PO3F2_MOUSE

Name: POU domain, class 3, transcription factor 2

UniProtKB Accession Codes:

P31360 A2AJY1

Database IDs:

Citations:

PubMed ID: 1565620

Title: Structure and evolution of four POU domain genes expressed in mouse brain.

PubMed ID: 1565620

DOI: 10.1073/pnas.89.8.3280

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 18505825

Title: Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors.

PubMed ID: 18505825

DOI: 10.1128/mcb.00338-08

PubMed ID: 18403418

Title: The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties.

PubMed ID: 18403418

DOI: 10.1093/nar/gkn162

PubMed ID: 20107439

Title: Direct conversion of fibroblasts to functional neurons by defined factors.

PubMed ID: 20107439

DOI: 10.1038/nature08797

PubMed ID: 24243019

Title: Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons.

PubMed ID: 24243019

DOI: 10.1016/j.cell.2013.09.028

PubMed ID: 24643061

Title: Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells.

PubMed ID: 24643061

DOI: 10.1371/journal.pone.0092105

PubMed ID: 27281220

Title: Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq.

PubMed ID: 27281220

DOI: 10.1038/nature18323

Sequence Information:

Length: 445
Mass: 47149
Checksum: 1A47F10950EECE8A
Sequence:

MATAASNHYS LLTSSASIVH AEPPGGMQQG AGGYREAQSL VQGDYGALQS NGHPLSHAHQ 
WITALSHGGG GGGGGGGGGG GGGGGGGGDG SPWSTSPLGQ PDIKPSVVVQ QGGRGDELHG 
PGALQQQHQQ QQQQQQQQQQ QQQQQQQQQQ QRPPHLVHHA ANHHPGPGAW RSAAAAAHLP 
PSMGASNGGL LYSQPSFTVN GMLGAGGQPA GLHHHGLRDA HDEPHHADHH PHPHSHPHQQ 
PPPPPPPQGP PGHPGAHHDP HSDEDTPTSD DLEQFAKQFK QRRIKLGFTQ ADVGLALGTL 
YGNVFSQTTI CRFEALQLSF KNMCKLKPLL NKWLEEADSS SGSPTSIDKI AAQGRKRKKR 
TSIEVSVKGA LESHFLKCPK PSAQEITSLA DSLQLEKEVV RVWFCNRRQK EKRMTPPGGT 
LPGAEDVYGG SRDTPPHHGV QTPVQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pou3f2

Associated with

Other Information

Structure and evolution of four POU domain genes expressed in mouse brain. PubMed ID: 1565620

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. PubMed ID: 18505825

The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. PubMed ID: 18403418

Direct conversion of fibroblasts to functional neurons by defined factors. PubMed ID: 20107439

Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. PubMed ID: 24243019

Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PubMed ID: 24643061

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq. PubMed ID: 27281220