Details for: Pou3f3

Gene ID: 18993

Symbol: Pou3f3

Ensembl ID: ENSMUSG00000045515

Description: POU domain, class 3, transcription factor 3

Associated with

  • Brain development
    (GO:0007420)
  • Cerebral cortex radially oriented cell migration
    (GO:0021799)
  • Chemical homeostasis
    (GO:0048878)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Forebrain ventricular zone progenitor cell division
    (GO:0021869)
  • Hmg box domain binding
    (GO:0071837)
  • Kidney development
    (GO:0001822)
  • Metanephric ascending thin limb development
    (GO:0072218)
  • Metanephric dct cell differentiation
    (GO:0072240)
  • Metanephric loop of henle development
    (GO:0072236)
  • Metanephric macula densa development
    (GO:0072227)
  • Metanephric thick ascending limb development
    (GO:0072233)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nervous system development
    (GO:0007399)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Urea transmembrane transport
    (GO:0071918)

Other Information

Genular Protein ID: 51736204

Symbol: PO3F3_MOUSE

Name: POU domain, class 3, transcription factor 3

UniProtKB Accession Codes:

P31361

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 GO 27 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 7 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 5 PROSITE-ProRule 2 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1565620

Title: Structure and evolution of four POU domain genes expressed in mouse brain.

PubMed ID: 1565620

DOI: 10.1073/pnas.89.8.3280

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 10473120

Title: An octamer-binding site is crucial for the activity of an enhancer active at the embryonic met-/mesencephalic junction.

PubMed ID: 10473120

DOI: 10.1016/s0925-4773(99)00067-2

PubMed ID: 12130536

Title: Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.

PubMed ID: 12130536

DOI: 10.1101/gad.978002

PubMed ID: 11859196

Title: Transcriptional regulation of cortical neuron migration by POU domain factors.

PubMed ID: 11859196

DOI: 10.1126/science.1067132

PubMed ID: 19527706

Title: Replacement of related POU transcription factors leads to severe defects in mouse forebrain development.

PubMed ID: 19527706

DOI: 10.1016/j.ydbio.2009.06.011

Sequence Information:

  • Length: 497
  • Mass: 50200
  • Checksum: 4B1860BEED53F8B0
  • Sequence:
    • MATAASNPYL PGNSLLTAGS IVHSDAAGAG GGGGGGGGGG GGAGGGGGGM QPGSAAVTSG 
AYRGDPSSVK MVQSDFMQGA MAASNGGHML SHAHQWVTAL PHAAAAAAAA AAAAVEASSP 
WSGSAVGMAG SPQQPPQPPP PPPQGPDVKG GAGREDLHAG TALHHRGPPH LGPPPPPPHQ 
GHPGGWGAAA AAAAAAAAAA AAAHLPSMAG GQQPPPQSLL YSQPGGFTVN GMLSAPPGPG 
GGGGGAGGGA QSLVHPGLVR GDTPELAEHH HHHHHHAHPH PPHPHHAQGP PHHGGGGAGP 
GLNSHDPHSD EDTPTSDDLE QFAKQFKQRR IKLGFTQADV GLALGTLYGN VFSQTTICRF 
EALQLSFKNM CKLKPLLNKW LEEADSSTGS PTSIDKIAAQ GRKRKKRTSI EVSVKGALES 
HFLKCPKPSA QEITNLADSL QLEKEVVRVW FCNRRQKEKR MTPPGIQQQT PDDVYSQVGT 
VSADTPPPHH GLQTSVQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.