Details for: Pou4f1

Gene ID: 18996

Symbol: Pou4f1

Ensembl ID: ENSMUSG00000048349

Description: POU domain, class 4, transcription factor 1

Associated with

Other Information

Genular Protein ID: 3774259310

Symbol: PO4F1_MOUSE

Name: POU domain, class 4, transcription factor 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8162704

Title: Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.

PubMed ID: 8162704

DOI: 10.1159/000133709

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 1970171

Title: Cloning and sequencing of POU-boxes expressed in mouse testis.

PubMed ID: 1970171

DOI: 10.1093/nar/18.6.1634

PubMed ID: 8290353

Title: Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.

PubMed ID: 8290353

DOI: 10.1093/nar/21.25.5921

PubMed ID: 8537352

Title: Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding.

PubMed ID: 8537352

DOI: 10.1074/jbc.270.52.30958

PubMed ID: 8621561

Title: The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site.

PubMed ID: 8621561

DOI: 10.1074/jbc.271.15.9108

PubMed ID: 8637595

Title: Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.

PubMed ID: 8637595

DOI: 10.1038/381603a0

PubMed ID: 8876243

Title: Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling.

PubMed ID: 8876243

DOI: 10.1073/pnas.93.21.11950

PubMed ID: 8972215

Title: The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins.

PubMed ID: 8972215

DOI: 10.1128/mcb.17.1.345

PubMed ID: 9448000

Title: POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element.

PubMed ID: 9448000

DOI: 10.1128/mcb.18.2.1029

PubMed ID: 9694219

Title: Functional role of position 22 in the homeodomain of Brn-3 transcription factors.

PubMed ID: 9694219

DOI: 10.1097/00001756-199807130-00029

PubMed ID: 9722627

Title: The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression.

PubMed ID: 9722627

DOI: 10.1093/nar/26.18.4100

PubMed ID: 10640682

Title: Regulation of NGFI-A (Egr-1) gene expression by the POU domain transcription factor Brn-3a.

PubMed ID: 10640682

DOI: 10.1016/s0169-328x(99)00271-5

PubMed ID: 12441296

Title: Direct autoregulation and gene dosage compensation by POU-domain transcription factor Brn3a.

PubMed ID: 12441296

DOI: 10.1242/dev.00194

PubMed ID: 12934100

Title: Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor.

PubMed ID: 12934100

DOI: 10.1038/sj.onc.1206635

PubMed ID: 17668438

Title: Brn3 transcription factors control terminal osteoclastogenesis.

PubMed ID: 17668438

DOI: 10.1002/jcb.21257

PubMed ID: 22326227

Title: Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.

PubMed ID: 22326227

DOI: 10.1016/j.ydbio.2012.01.021

Sequence Information:

  • Length: 421
  • Mass: 42767
  • Checksum: 64EC98E5C0CF79E2
  • Sequence:
  • MMSMNSKQPH FAMHPTLPEH KYPSLHSSSE AIRRACLPTP PLQSNLFASL DETLLARAEA 
    LAAVDIAVSQ GKSHPFKPDA TYHTMNSVPC TSTSTVPLAH HHHHHHHHQA LEPGDLLDHI 
    SSPSLALMAG AGGAGAAGGG GGAHDGPGGG GGPGGGGGPG GGGPGGGGGG GGPGGGGGGP 
    GGGLLGGSAH PHPHMHGLGH LSHPAAAAAM NMPSGLPHPG LVAAAAHHGA AAAAAAAAAG 
    QVAAASAAAA VVGAAGLASI CDSDTDPREL EAFAERFKQR RIKLGVTQAD VGSALANLKI 
    PGVGSLSQST ICRFESLTLS HNNMIALKPI LQAWLEEAEG AQREKMNKPE LFNGGEKKRK 
    RTSIAAPEKR SLEAYFAVQP RPSSEKIAAI AEKLDLKKNV VRVWFCNQRQ KQKRMKFSAT 
    Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.