Genular: Defining Cellular Identity and Function

Details for: Pou4f3

Gene ID: 18998

Symbol: Pou4f3

Ensembl ID: ENSMUSG00000024497

Description: POU domain, class 4, transcription factor 3

Associated with

Axon extension
(GO:0048675)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Inner ear auditory receptor cell differentiation
(GO:0042491)
Inner ear development
(GO:0048839)
Inner ear morphogenesis
(GO:0042472)
Inner ear receptor cell differentiation
(GO:0060113)
Neuromuscular process controlling balance
(GO:0050885)
Neuron apoptotic process
(GO:0051402)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Retinal ganglion cell axon guidance
(GO:0031290)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sensory perception of sound
(GO:0007605)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription regulator complex
(GO:0005667)
Vestibulocochlear nerve development
(GO:0021562)

Other Information

Proteins

Brain-specific homeobox/POU domain protein 3C

Genular Protein ID: 1847084803

Symbol: PO4F3_MOUSE

Name: Brain-specific homeobox/POU domain protein 3C

UniProtKB Accession Codes:

Q63955 A6H6N6

Database IDs:

Citations:

PubMed ID: 8162704

Title: Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.

PubMed ID: 8162704

DOI: 10.1159/000133709

PubMed ID: 8248179

Title: Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.

PubMed ID: 8248179

DOI: 10.1073/pnas.90.22.10841

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8290353

Title: Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.

PubMed ID: 8290353

DOI: 10.1093/nar/21.25.5921

PubMed ID: 7935408

Title: The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.

PubMed ID: 7935408

DOI: 10.1128/mcb.14.10.6907-6914.1994

PubMed ID: 8637595

Title: Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.

PubMed ID: 8637595

DOI: 10.1038/381603a0

PubMed ID: 22326227

Title: Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.

PubMed ID: 22326227

DOI: 10.1016/j.ydbio.2012.01.021

PubMed ID: 24643061

Title: Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells.

PubMed ID: 24643061

DOI: 10.1371/journal.pone.0092105

Sequence Information:

Length: 338
Mass: 37016
Checksum: 4B7C78BD788FB944
Sequence:

MMAMNAKQPF GMHPVLQEPK FSSLHSGSEA MRRVCLPAPQ LQGNIFGSFD ESLLARAEAL 
AAVDIVSHGK NHPFKPDATY HTMSSVPCTS TSPTVPISHP AALTSHPHHA VHQGLEGDLL 
EHISPTLSVS GLGAPEHSVM PAQIHPHHLG AMGHLHQAMG MSHPHAVAPH SAMPACLSDV 
ESDPRELEAF AERFKQRRIK LGVTQADVGA ALANLKIPGV GSLSQSTICR FESLTLSHNN 
MIALKPVLQA WLEEAEAAYR EKNSKPELFN GSERKRKRTS IAAPEKRSLE AYFAIQPRPS 
SEKIAAIAEK LDLKKNVVRV WFCNQRQKQK RMKYSAVH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pou4f3

Associated with

Other Information

Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes. PubMed ID: 8162704

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. PubMed ID: 8248179

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a. PubMed ID: 8290353

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain. PubMed ID: 7935408

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. PubMed ID: 8637595

Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. PubMed ID: 22326227

Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PubMed ID: 24643061