Genular: Defining Cellular Identity and Function

Details for: Ppp1cb

Gene ID: 19046

Symbol: Ppp1cb

Ensembl ID: ENSMUSG00000014956

Description: protein phosphatase 1 catalytic subunit beta

Associated with

Cell cycle, mitotic
(R-MMU-69278)
G2/m transition
(R-MMU-69275)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Mitotic g2-g2/m phases
(R-MMU-453274)
Raf/map kinase cascade
(R-MMU-5673001)
Raf activation
(R-MMU-5673000)
Regulation of plk1 activity at g2/m transition
(R-MMU-2565942)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate paks
(R-MMU-5627123)
Rho gtpases activate pkns
(R-MMU-5625740)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Carbohydrate metabolic process
(GO:0005975)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Chromosome, telomeric region
(GO:0000781)
Circadian regulation of gene expression
(GO:0032922)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Glycogen granule
(GO:0042587)
Glycogen metabolic process
(GO:0005977)
Hydrolase activity
(GO:0016787)
Metal ion binding
(GO:0046872)
Myosin-light-chain-phosphatase activity
(GO:0050115)
Myosin phosphatase activity
(GO:0017018)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Phosphatase activity
(GO:0016791)
Phosphoprotein phosphatase activity
(GO:0004721)
Protein binding
(GO:0005515)
Protein dephosphorylation
(GO:0006470)
Protein kinase binding
(GO:0019901)
Protein phosphatase type 1 complex
(GO:0000164)
Protein serine/threonine phosphatase activity
(GO:0004722)
Ptw/pp1 phosphatase complex
(GO:0072357)
Regulation of cell adhesion
(GO:0030155)
Regulation of circadian rhythm
(GO:0042752)
Regulation of glycogen biosynthetic process
(GO:0005979)
Regulation of glycogen catabolic process
(GO:0005981)
Rhythmic process
(GO:0048511)

Other Information

Proteins

Serine/threonine-protein phosphatase PP1-beta catalytic subunit

Genular Protein ID: 3568761788

Symbol: PP1B_MOUSE

Name: Serine/threonine-protein phosphatase PP1-beta catalytic subunit

UniProtKB Accession Codes:

P62141 P37140 Q3TBE5 Q3TL90 Q542E7 Q8C285 Q9DBY2

Database IDs:

Citations:

PubMed ID: 2544298

Title: The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.

PubMed ID: 2544298

DOI: 10.1016/0092-8674(89)90338-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14638860

Title: Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.

PubMed ID: 14638860

DOI: 10.1083/jcb.200308075

PubMed ID: 16835242

Title: Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress.

PubMed ID: 16835242

DOI: 10.1074/jbc.m513556200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21712997

Title: Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.

PubMed ID: 21712997

DOI: 10.1371/journal.pone.0021325

PubMed ID: 21930935

Title: The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.

PubMed ID: 21930935

DOI: 10.1073/pnas.1107178108

Sequence Information:

Length: 327
Mass: 37187
Checksum: E8356022E9B94ECD
Sequence:

MADGELNVDS LITRLLEVRG CRPGKIVQMT EAEVRGLCIK SREIFLSQPI LLELEAPLKI 
CGDIHGQYTD LLRLFEYGGF PPEANYLFLG DYVDRGKQSL ETICLLLAYK IKYPENFFLL 
RGNHECASIN RIYGFYDECK RRFNIKLWKT FTDCFNCLPI AAIVDEKIFC CHGGLSPDLQ 
SMEQIRRIMR PTDVPDTGLL CDLLWSDPDK DVQGWGENDR GVSFTFGADV VSKFLNRHDL 
DLICRAHQVV EDGYEFFAKR QLVTLFSAPN YCGEFDNAGG MMSVDETLMC SFQILKPSEK 
KAKYQYGGLN SGRPVTPPRT ANPPKKR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ppp1cb

Associated with

Other Information

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. PubMed ID: 2544298

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells. PubMed ID: 14638860

Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress. PubMed ID: 16835242

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock. PubMed ID: 21712997

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. PubMed ID: 21930935