Genular: Defining Cellular Identity and Function

Details for: Ppp2cb

Gene ID: 19053

Symbol: Ppp2cb

Ensembl ID: ENSMUSG00000009630

Description: protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform

Associated with

Adaptive immune system
(R-MMU-1280218)
Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Antiviral mechanism by ifn-stimulated genes
(R-MMU-1169410)
Beta-catenin phosphorylation cascade
(R-MMU-196299)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Costimulation by the cd28 family
(R-MMU-388841)
Ctla4 inhibitory signaling
(R-MMU-389513)
Cyclin a/b1/b2 associated events during g2/m transition
(R-MMU-69273)
Cyclin d associated events in g1
(R-MMU-69231)
Cytokine signaling in immune system
(R-MMU-1280215)
Darpp-32 events
(R-MMU-180024)
Degradation of beta-catenin by the destruction complex
(R-MMU-195253)
Disassembly of the destruction complex and recruitment of axin to the membrane
(R-MMU-4641262)
E2f mediated regulation of dna replication
(R-MMU-113510)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
Erk/mapk targets
(R-MMU-198753)
G1 phase
(R-MMU-69236)
G1/s transition
(R-MMU-69206)
G2/m transition
(R-MMU-69275)
G alpha (i) signalling events
(R-MMU-418594)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Gpcr downstream signalling
(R-MMU-388396)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Inhibition of replication initiation of damaged dna by rb1/e2f1
(R-MMU-113501)
Innate immune system
(R-MMU-168249)
Interferon signaling
(R-MMU-913531)
Interleukin-17 signaling
(R-MMU-448424)
Intracellular signaling by second messengers
(R-MMU-9006925)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Map kinase activation
(R-MMU-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-MMU-450282)
Mitotic anaphase
(R-MMU-68882)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Mitotic g2-g2/m phases
(R-MMU-453274)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Myd88 cascade initiated on plasma membrane
(R-MMU-975871)
Myd88 dependent cascade initiated on endosome
(R-MMU-975155)
Myd88-independent tlr4 cascade
(R-MMU-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-MMU-166058)
Negative regulation of fgfr1 signaling
(R-MMU-5654726)
Negative regulation of fgfr2 signaling
(R-MMU-5654727)
Negative regulation of fgfr3 signaling
(R-MMU-5654732)
Negative regulation of fgfr4 signaling
(R-MMU-5654733)
Negative regulation of mapk pathway
(R-MMU-5675221)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Nuclear events (kinase and transcription factor activation)
(R-MMU-198725)
Opioid signalling
(R-MMU-111885)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Pkr-mediated signaling
(R-MMU-9833482)
Platelet homeostasis
(R-MMU-418346)
Platelet sensitization by ldl
(R-MMU-432142)
Raf/map kinase cascade
(R-MMU-5673001)
Raf activation
(R-MMU-5673000)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 degradation
(R-MMU-6804757)
Regulation of tp53 expression and degradation
(R-MMU-6806003)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Rna polymerase ii transcription
(R-MMU-73857)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by fgfr3
(R-MMU-5654741)
Signaling by fgfr4
(R-MMU-5654743)
Signaling by gpcr
(R-MMU-372790)
Signaling by interleukins
(R-MMU-449147)
Signaling by ntrk1 (trka)
(R-MMU-187037)
Signaling by ntrks
(R-MMU-166520)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
Spry regulation of fgf signaling
(R-MMU-1295596)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Toll-like receptor cascades
(R-MMU-168898)
Toll like receptor 2 (tlr2) cascade
(R-MMU-181438)
Toll like receptor 3 (tlr3) cascade
(R-MMU-168164)
Toll like receptor 4 (tlr4) cascade
(R-MMU-166016)
Toll like receptor 5 (tlr5) cascade
(R-MMU-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-MMU-168181)
Toll like receptor 9 (tlr9) cascade
(R-MMU-168138)
Toll like receptor 10 (tlr10) cascade
(R-MMU-168142)
Toll like receptor tlr1:tlr2 cascade
(R-MMU-168179)
Toll like receptor tlr6:tlr2 cascade
(R-MMU-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-MMU-975138)
Transcriptional regulation by tp53
(R-MMU-3700989)
Trif(ticam1)-mediated tlr4 signaling
(R-MMU-937061)

Other Information

Proteins

Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Q8BN07_MOUSE

Genular Protein ID: 2013690256

Symbol: PP2AB_MOUSE

Name: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

UniProtKB Accession Codes:

P62715 P11082

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8077208

Title: Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain.

PubMed ID: 8077208

DOI: 10.1016/s0021-9258(17)31686-1

PubMed ID: 7510677

Title: Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts.

PubMed ID: 7510677

DOI: 10.1016/s0021-9258(17)37144-2

PubMed ID: 10441131

Title: Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2.

PubMed ID: 10441131

DOI: 10.1021/bi990902g

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25546391

Title: The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development.

PubMed ID: 25546391

DOI: 10.1371/journal.pone.0116150

Sequence Information:

Length: 309
Mass: 35575
Checksum: 51DA9EB0633FC191
Sequence:

MDDKAFTKEL DQWVEQLNEC KQLNENQVRT LCEKAKEILT KESNVQEVRC PVTVCGDVHG 
QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER ITILRGNHES 
RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI 
RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA 
HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV 
TRRTPDYFL

Genular Protein ID: 659686126

Symbol: Q8BN07_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BN07

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 285
Mass: 32644
Checksum: F6554898D5967259
Sequence:

ENQVRTLCEK AKEILTKESN VQEVRCPVTV CGDVHGQFHD LMELFRIGGK SPDTNYLFMG 
DYVDRGYYSV ETVTLLVALK VRYPERITIL RGNHESRQIT QVYGFYDECL RKYGNANVWK 
YFTDLFDYLP LTALVDGQIF CLNGGLSPSI DTLDHIRALD RLQEVPHEGP MCDLLWSDPD 
DRGGWGISPR GAGYTFGQDI SETFNHANGL TLVSRAHQLV MEGYNWCHDR NVVTIFSAPN 
YCYRCGNQAA IMELDDTLKY SFLQFDPAPR RGEPHVTRRT PDYFL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ppp2cb

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain. PubMed ID: 8077208

Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts. PubMed ID: 7510677

Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2. PubMed ID: 10441131

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development. PubMed ID: 25546391

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073