Genular: Defining Cellular Identity and Function

Details for: Prkar1a

Gene ID: 19084

Symbol: Prkar1a

Ensembl ID: ENSMUSG00000020612

Description: protein kinase, cAMP dependent regulatory, type I, alpha

Associated with

Activation of nmda receptors and postsynaptic events
(R-MMU-442755)
Aquaporin-mediated transport
(R-MMU-445717)
Ca-dependent events
(R-MMU-111996)
Calmodulin induced events
(R-MMU-111933)
Cam pathway
(R-MMU-111997)
Creb1 phosphorylation through the activation of adenylate cyclase
(R-MMU-442720)
Dag and ip3 signaling
(R-MMU-1489509)
Darpp-32 events
(R-MMU-180024)
Factors involved in megakaryocyte development and platelet production
(R-MMU-983231)
G-protein mediated events
(R-MMU-112040)
G alpha (i) signalling events
(R-MMU-418594)
G alpha (s) signalling events
(R-MMU-418555)
Glucagon signaling in metabolic regulation
(R-MMU-163359)
Gpcr downstream signalling
(R-MMU-388396)
Gper1 signaling
(R-MMU-9634597)
Hedgehog 'off' state
(R-MMU-5610787)
Hemostasis
(R-MMU-109582)
Integration of energy metabolism
(R-MMU-163685)
Intracellular signaling by second messengers
(R-MMU-9006925)
Metabolism
(R-MMU-1430728)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Opioid signalling
(R-MMU-111885)
Pka-mediated phosphorylation of creb
(R-MMU-111931)
Pka activation
(R-MMU-163615)
Pka activation in glucagon signalling
(R-MMU-164378)
Plc beta mediated events
(R-MMU-112043)
Post nmda receptor activation events
(R-MMU-438064)
Signaling by gpcr
(R-MMU-372790)
Signaling by hedgehog
(R-MMU-5358351)
Signal transduction
(R-MMU-162582)
Transmission across chemical synapses
(R-MMU-112315)
Transport of small molecules
(R-MMU-382551)
Vasopressin regulates renal water homeostasis via aquaporins
(R-MMU-432040)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Animal organ morphogenesis
(GO:0009887)
Axoneme
(GO:0005930)
Camp-dependent protein kinase complex
(GO:0005952)
Camp-dependent protein kinase inhibitor activity
(GO:0004862)
Camp-dependent protein kinase regulator activity
(GO:0008603)
Camp binding
(GO:0030552)
Cardiac muscle cell proliferation
(GO:0060038)
Cellular response to glucagon stimulus
(GO:0071377)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Glutamatergic synapse
(GO:0098978)
Heart development
(GO:0007507)
Immunological synapse
(GO:0001772)
Membrane
(GO:0016020)
Mesenchymal cell proliferation
(GO:0010463)
Mesoderm formation
(GO:0001707)
Multivesicular body
(GO:0005771)
Negative regulation of activated t cell proliferation
(GO:0046007)
Negative regulation of camp-dependent protein kinase activity
(GO:2000480)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of protein kinase activity
(GO:0006469)
Neuromuscular junction
(GO:0031594)
Nucleotide-activated protein kinase complex
(GO:0031588)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Plasma membrane raft
(GO:0044853)
Positive regulation of insulin secretion
(GO:0032024)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase a catalytic subunit binding
(GO:0034236)
Protein phosphorylation
(GO:0006468)
Sarcomere organization
(GO:0045214)
Sperm connecting piece
(GO:0097224)
Synapse
(GO:0045202)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

cAMP-dependent protein kinase type I-alpha regulatory subunit

Genular Protein ID: 3387691913

Symbol: KAP0_MOUSE

Name: cAMP-dependent protein kinase type I-alpha regulatory subunit

UniProtKB Accession Codes:

Q9DBC7 Q3UKU7 Q9JHR5 Q9JHR6

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10913627

Title: Alternative 5'-exons of the mouse cAMP-dependent protein kinase subunit RIalpha gene are conserved and expressed in both a ubiquitous and tissue-restricted fashion.

PubMed ID: 10913627

DOI: 10.1016/s0014-5793(00)01653-7

PubMed ID: 9852104

Title: Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1.

PubMed ID: 9852104

DOI: 10.1074/jbc.273.51.34384

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20138877

Title: Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PubMed ID: 20138877

DOI: 10.1016/j.febslet.2010.02.007

Sequence Information:

Length: 381
Mass: 43185
Checksum: 08F164BB4528C63B
Sequence:

MASGSMATSE EERSLRECEL YVQKHNIQAL LKDSIVQLCT TRPERPMAFL REYFERLEKE 
EARQIQCLQK TGIRTDSRED EISPPPPNPV VKGRRRRGAI SAEVYTEEDA ASYVRKVIPK 
DYKTMAALAK AIEKNVLFSH LDDNERSDIF DAMFPVSFIA GETVIQQGDE GDNFYVIDQG 
EMDVYVNNEW ATSVGEGGSF GELALIYGTP RAATVKAKTN VKLWGIDRDS YRRILMGSTL 
RKRKMYEEFL SKVSILESLD KWERLTVADA LEPVQFEDGQ KIVVQGEPGD EFFIILEGTA 
AVLQRRSENE EFVEVGRLGP SDYFGEIALL MNRPRAATVV ARGPLKCVKL DRPRFERVLG 
PCSDILKRNI QQYNSFVSLS V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prkar1a

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Alternative 5'-exons of the mouse cAMP-dependent protein kinase subunit RIalpha gene are conserved and expressed in both a ubiquitous and tissue-restricted fashion. PubMed ID: 10913627

Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1. PubMed ID: 9852104

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner. PubMed ID: 20138877