Genular: Defining Cellular Identity and Function

Details for: Proc

Gene ID: 19123

Symbol: Proc

Ensembl ID: ENSMUSG00000024386

Description: protein C

Associated with

Cell surface interactions at the vascular wall
(R-MMU-202733)
Common pathway of fibrin clot formation
(R-MMU-140875)
Formation of fibrin clot (clotting cascade)
(R-MMU-140877)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
(R-MMU-159854)
Gamma-carboxylation of protein precursors
(R-MMU-159740)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-MMU-163841)
Intrinsic pathway of fibrin clot formation
(R-MMU-140837)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Removal of aminoterminal propeptides from gamma-carboxylated proteins
(R-MMU-159782)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the golgi apparatus
(R-MMU-159763)
Blood coagulation
(GO:0007596)
Calcium ion binding
(GO:0005509)
Endoplasmic reticulum
(GO:0005783)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Hemostasis
(GO:0007599)
Hydrolase activity
(GO:0016787)
Liver development
(GO:0001889)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of blood coagulation
(GO:0030195)
Negative regulation of coagulation
(GO:0050819)
Negative regulation of inflammatory response
(GO:0050728)
Oligopeptidase activity
(GO:0070012)
Peptidase activity
(GO:0008233)
Positive regulation of establishment of endothelial barrier
(GO:1903142)
Protein catabolic process
(GO:0030163)
Protein self-association
(GO:0043621)
Proteolysis
(GO:0006508)
Regulation of circulating fibrinogen levels
(GO:0044537)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)

Other Information

Proteins

Vitamin K-dependent protein C

Genular Protein ID: 2490777730

Symbol: PROC_MOUSE

Name: Vitamin K-dependent protein C

UniProtKB Accession Codes:

P33587 O35498 Q91WN8 Q99PC6

Database IDs:

Citations:

PubMed ID: 1618739

Title: Isolation and characterization of a mouse protein C cDNA.

PubMed ID: 1618739

DOI: 10.1093/oxfordjournals.jbchem.a123785

PubMed ID: 9493582

Title: Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C.

PubMed ID: 9493582

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8043441

Title: A comparative study of partial primary structures of the catalytic region of mammalian protein C.

PubMed ID: 8043441

DOI: 10.1111/j.1365-2141.1994.tb04791.x

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

Sequence Information:

Length: 460
Mass: 51818
Checksum: 0117F26E68FCC274
Sequence:

MWQFRVFLLL MSTWGISSIP AHPDPVFSSS EHAHQVLRVR RANSFLEEMR PGSLERECME 
EICDFEEAQE IFQNVEDTLA FWIKYFDGDQ CSAPPLDHQC DSPCCGHGTC IDGIGSFSCS 
CDKGWEGKFC QQELRFQDCR VNNGGCLHYC LEESNGRRCA CAPGYELADD HMRCKSTVNF 
PCGKLGRWIE KKRKILKRDT DLEDELEPDP RIVNGTLTKQ GDSPWQAILL DSKKKLACGG 
VLIHTSWVLT AAHCVEGTKK LTVRLGEYDL RRRDHWELDL DIKEILVHPN YTRSSSDNDI 
ALLRLAQPAT LSKTIVPICL PNNGLAQELT QAGQETVVTG WGYQSDRIKD GRRNRTFILT 
FIRIPLVARN ECVEVMKNVV SENMLCAGII GDTRDACDGD SGGPMVVFFR GTWFLVGLVS 
WGEGCGHTNN YGIYTKVGSY LKWIHSYIGE KGVSLKSQKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Proc

Associated with

Other Information

Isolation and characterization of a mouse protein C cDNA. PubMed ID: 1618739

Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C. PubMed ID: 9493582

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334