Genular: Defining Cellular Identity and Function

Details for: Prop1

Gene ID: 19127

Symbol: Prop1

Ensembl ID: ENSMUSG00000044542

Description: paired like homeodomain factor 1

Associated with

Adenohypophysis development
(GO:0021984)
Animal organ morphogenesis
(GO:0009887)
Apoptotic process
(GO:0006915)
Beta-catenin binding
(GO:0008013)
Blood vessel development
(GO:0001568)
Cell migration
(GO:0016477)
Chromatin binding
(GO:0003682)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Dorsal/ventral pattern formation
(GO:0009953)
Gland development
(GO:0048732)
Hypophysis morphogenesis
(GO:0048850)
Hypothalamus cell differentiation
(GO:0021979)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Pituitary gland development
(GO:0021983)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)
Somatotropin secreting cell differentiation
(GO:0060126)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Homeobox protein prophet of Pit-1

Genular Protein ID: 1340088878

Symbol: PROP1_MOUSE

Name: Homeobox protein prophet of Pit-1

UniProtKB Accession Codes:

P97458 Q5NCG9

Database IDs:

Citations:

PubMed ID: 8934515

Title: Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism.

PubMed ID: 8934515

DOI: 10.1038/384327a0

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 10946881

Title: Combined pituitary hormone deficiency caused by a novel mutation of a highly conserved residue (F88S) in the homeodomain of PROP-1.

PubMed ID: 10946881

DOI: 10.1210/jcem.85.8.6744

Sequence Information:

Length: 223
Mass: 25025
Checksum: CD0AC4DFDC383679
Sequence:

MEAQRRSHQE KQTKGHACGR SLPEPRVASG TLISTVDRSS EAYRRLSGTE LGRPKLCPQR 
GRPHSRRRHR TTFNPAQLEQ LESAFGRNQY PDIWAREGLA QDTGLSEARI QVWFQNRRAK 
QRKQERSLLQ PIAHLSTATF SGFLPESSAY PYTYGTPPPP APCFPHPYSH SLPSQPSTAA 
SLALPPQPED WYPTLHPAPT GHLPCPPPPP MFPLSLETPK SWN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.