Genular: Defining Cellular Identity and Function

Details for: Psmc3

Gene ID: 19182

Symbol: Psmc3

Ensembl ID: ENSMUSG00000002102

Description: proteasome (prosome, macropain) 26S subunit, ATPase 3

Associated with

Abc-family proteins mediated transport
(R-MMU-382556)
Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
(R-MMU-176814)
Activation of nf-kappab in b cells
(R-MMU-1169091)
Adaptive immune system
(R-MMU-1280218)
Antigen processing-cross presentation
(R-MMU-1236975)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Apc/c-mediated degradation of cell cycle proteins
(R-MMU-174143)
Apc/c:cdh1 mediated degradation of cdc20 and other apc/c:cdh1 targeted proteins in late mitosis/early g1
(R-MMU-174178)
Assembly of the pre-replicative complex
(R-MMU-68867)
Asymmetric localization of pcp proteins
(R-MMU-4608870)
Auf1 (hnrnp d0) binds and destabilizes mrna
(R-MMU-450408)
Autodegradation of cdh1 by cdh1:apc/c
(R-MMU-174084)
Beta-catenin independent wnt signaling
(R-MMU-3858494)
C-type lectin receptors (clrs)
(R-MMU-5621481)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Cellular response to hypoxia
(R-MMU-1234174)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Clec7a (dectin-1) signaling
(R-MMU-5607764)
Cross-presentation of soluble exogenous antigens (endosomes)
(R-MMU-1236978)
Cyclin a:cdk2-associated events at s phase entry
(R-MMU-69656)
Cytokine signaling in immune system
(R-MMU-1280215)
Dectin-1 mediated noncanonical nf-kb signaling
(R-MMU-5607761)
Degradation of axin
(R-MMU-4641257)
Degradation of beta-catenin by the destruction complex
(R-MMU-195253)
Degradation of dvl
(R-MMU-4641258)
Degradation of gli1 by the proteasome
(R-MMU-5610780)
Deubiquitination
(R-MMU-5688426)
Dna replication
(R-MMU-69306)
Dna replication pre-initiation
(R-MMU-69002)
Downstream signaling events of b cell receptor (bcr)
(R-MMU-1168372)
Downstream tcr signaling
(R-MMU-202424)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated nf-kb activation
(R-MMU-2871837)
G1/s dna damage checkpoints
(R-MMU-69615)
G1/s transition
(R-MMU-69206)
G2/m checkpoints
(R-MMU-69481)
G2/m transition
(R-MMU-69275)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Gli3 is processed to gli3r by the proteasome
(R-MMU-5610785)
Hedgehog 'off' state
(R-MMU-5610787)
Hedgehog 'on' state
(R-MMU-5632684)
Hedgehog ligand biogenesis
(R-MMU-5358346)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interleukin-1 family signaling
(R-MMU-446652)
Intracellular signaling by second messengers
(R-MMU-9006925)
Keap1-nfe2l2 pathway
(R-MMU-9755511)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk6/mapk4 signaling
(R-MMU-5687128)
Mapk family signaling cascades
(R-MMU-5683057)
Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Metabolism of polyamines
(R-MMU-351202)
Metabolism of proteins
(R-MMU-392499)
Metabolism of rna
(R-MMU-8953854)
Mitotic anaphase
(R-MMU-68882)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Mitotic g2-g2/m phases
(R-MMU-453274)
Mitotic metaphase and anaphase
(R-MMU-2555396)
M phase
(R-MMU-68886)
Neddylation
(R-MMU-8951664)
Neutrophil degranulation
(R-MMU-6798695)
Nik-->noncanonical nf-kb signaling
(R-MMU-5676590)
Oxygen-dependent proline hydroxylation of hypoxia-inducible factor alpha
(R-MMU-1234176)
P53-dependent g1/s dna damage checkpoint
(R-MMU-69580)
P53-independent g1/s dna damage checkpoint
(R-MMU-69613)
Pcp/ce pathway
(R-MMU-4086400)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Pten regulation
(R-MMU-6807070)
Raf/map kinase cascade
(R-MMU-5673001)
Regulation of mitotic cell cycle
(R-MMU-453276)
Regulation of mrna stability by proteins that bind au-rich elements
(R-MMU-450531)
Regulation of ornithine decarboxylase (odc)
(R-MMU-350562)
Regulation of ras by gaps
(R-MMU-5658442)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by hedgehog
(R-MMU-5358351)
Signaling by interleukins
(R-MMU-449147)
Signaling by the b cell receptor (bcr)
(R-MMU-983705)
Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
S phase
(R-MMU-69242)
Switching of origins to a post-replicative state
(R-MMU-69052)
Synthesis of dna
(R-MMU-69239)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Tcr signaling
(R-MMU-202403)
Tnfr2 non-canonical nf-kb pathway
(R-MMU-5668541)
Transcriptional regulation by runx1
(R-MMU-8878171)
Transcriptional regulation by runx2
(R-MMU-8878166)
Transcriptional regulation by runx3
(R-MMU-8878159)
Transport of small molecules
(R-MMU-382551)
Ub-specific processing proteases
(R-MMU-5689880)
Ubiquitin-dependent degradation of cyclin d
(R-MMU-75815)
Uch proteinases
(R-MMU-5689603)

Other Information

Proteins

26S proteasome regulatory subunit 6A
Q3TKG4_MOUSE

Genular Protein ID: 650130166

Symbol: PRS6A_MOUSE

Name: 26S proteasome regulatory subunit 6A

UniProtKB Accession Codes:

O88685 Q99JN8

Database IDs:

Citations:

PubMed ID: 9714759

Title: Cloning and heterogeneous in vivo expression of Tat binding protein-1 (TBP-1) in the mouse.

PubMed ID: 9714759

DOI: 10.1016/s0167-4781(98)00105-5

PubMed ID: 10945464

Title: Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting.

PubMed ID: 10945464

DOI: 10.1006/geno.2000.6231

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16857966

Title: Mapping the murine cardiac 26S proteasome complexes.

PubMed ID: 16857966

DOI: 10.1161/01.res.0000237386.98506.f7

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22078707

Title: TRIM5alpha associates with proteasomal subunits in cells while in complex with HIV-1 virions.

PubMed ID: 22078707

DOI: 10.1186/1742-4690-8-93

Sequence Information:

Length: 442
Mass: 49549
Checksum: AECCFD5BAFF26C5B
Sequence:

MQEMNLLPTP ESPVTRQEKM ATVWDEAEQD GIGEEVLKMS TEEIVQRTRL LDSEIKIMKS 
EVLRVTHELQ AMKDKIKENS EKIKVNKTLP YLVSNVIELL DVDPNDQEED GANIDLDSQR 
KGKCAVIKTS TRQTYFLPVI GLVDAEKLKP GDLVGVNKDS YLILETLPTE YDSRVKAMEV 
DERPTEQYSD IGGLDKQIQE LVEAIVLPMN HKEKFENLGI QPPKGVLMYG PPGTGKTLLA 
RACAAQTKAT FLKLAGPQLV QMFIGDGAKL VRDAFALAKE KAPSIIFIDE LDAIGTKRFD 
SEKAGDREVQ RTMLELLNQL DGFQPNTQVK VIAATNRVDI LDPALLRSGR LDRKIEFPMP 
NEEARARIMQ IHSRKMNVSP DVNYEELARC TDDFNGAQCK AVCVEAGMIA LRRGATELTH 
EDYMEGILEV QAKKKANLQY YA

Genular Protein ID: 628105930

Symbol: Q3TKG4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TKG4

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 502
Mass: 55638
Checksum: 9A985D53C91A7EB7
Sequence:

GSLGLVRGVP AADSLGDADR TRSVASGIAG EVLHGWREDV EKGCAGLPQG LVRTPSFGLF 
MQEMNLLPTP ESPVTRQEKM ATVWDEAEQD GIGEEVLKMS TEEIVQRTRL LDSEIKIMKS 
EVLRVTHELQ AMKDKIKENS EKIKVNKTLP YLVSNVIELL DVDPNDQEED GANIDLDSQR 
KGKCAVIKTS TRQTYFLPVI GLVDAEKLKP GDLVGVNKDS YLILETLPTE YDSRVKAMEV 
DERPTEQYSD IGGLDKQIQE LVEAIVLPMN HKEKFENLGI QPPKGVLMYG PPGTGKTLLA 
RACAAQTKAT FLKLAGPQLV QMFIGDGAKL VRDAFALAKE KAPSIIFIDE LDAIGTKRFD 
SEKAGDREVQ RTMLELLNQL DGFQPNTQVK VIAATNRVDI LDPALLRSGR LDRKIEFPMP 
NEEARARIMQ IHSRKMNVSP DVNYEELARC TDDFNGAQCK AVCVEAGMIA LRRGATELTH 
EDYMEGILEV QAKKKANLQY YA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Psmc3

Associated with

Other Information

Cloning and heterogeneous in vivo expression of Tat binding protein-1 (TBP-1) in the mouse. PubMed ID: 9714759

Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting. PubMed ID: 10945464

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mapping the murine cardiac 26S proteasome complexes. PubMed ID: 16857966

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

TRIM5alpha associates with proteasomal subunits in cells while in complex with HIV-1 virions. PubMed ID: 22078707

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073