Genular: Defining Cellular Identity and Function

Details for: Ptafr

Gene ID: 19204

Symbol: Ptafr

Ensembl ID: ENSMUSG00000056529

Description: platelet-activating factor receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Signaling by gpcr
(R-MMU-372790)
Chemotaxis
(GO:0006935)
Cytokine production
(GO:0001816)
G protein-coupled purinergic nucleotide receptor activity
(GO:0045028)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Inflammatory response
(GO:0006954)
Inositol trisphosphate biosynthetic process
(GO:0032959)
Lipopolysaccharide binding
(GO:0001530)
Lipopolysaccharide immune receptor activity
(GO:0001875)
Membrane
(GO:0016020)
Mitogen-activated protein kinase binding
(GO:0051019)
Negative regulation of blood pressure
(GO:0045776)
Parturition
(GO:0007567)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Platelet activating factor receptor activity
(GO:0004992)
Positive regulation of cellular extravasation
(GO:0002693)
Positive regulation of gastro-intestinal system smooth muscle contraction
(GO:1904306)
Positive regulation of inositol phosphate biosynthetic process
(GO:0060732)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of leukocyte cell-cell adhesion
(GO:1903039)
Positive regulation of leukocyte tethering or rolling
(GO:1903238)
Positive regulation of maternal process involved in parturition
(GO:1904303)
Positive regulation of neutrophil degranulation
(GO:0043315)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Positive regulation of smooth muscle contraction
(GO:0045987)
Positive regulation of transcytosis
(GO:1904300)
Positive regulation of translation
(GO:0045727)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to lipopolysaccharide
(GO:0032496)
Signal transduction
(GO:0007165)
Transcytosis
(GO:0045056)

Other Information

Proteins

Platelet-activating factor receptor

Genular Protein ID: 1379597403

Symbol: PTAFR_MOUSE

Name: Platelet-activating factor receptor

UniProtKB Accession Codes:

Q62035 B1B170 Q8C017

Database IDs:

Citations:

PubMed ID: 8670084

Title: A murine platelet-activating factor receptor gene: cloning, chromosomal localization and up-regulation of expression by lipopolysaccharide in peritoneal resident macrophages.

PubMed ID: 8670084

DOI: 10.1042/bj3140671

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

Sequence Information:

Length: 341
Mass: 39148
Checksum: CAA8CDDBD8D26897
Sequence:

MEHNGSFRVD SEFRYTLFPI VYSVIFILGV VANGYVLWVF ANLYPSKKLN EIKIFMVNLT 
MADLLFLITL PLWIVYYYNE GDWILPNFLC NVAGCLFFIN TYCSVAFLGV ITYNRYQAVA 
YPIKTAQATT RKRGISLSLI IWVSIVATAS YFLATDSTNL VPNKDGSGNI TRCFEHYEPY 
SVPILVVHVF IAFCFFLVFF LIFYCNLVII HTLLTQPMRQ QRKAGVKRRA LWMVCTVLAV 
FIICFVPHHV VQLPWTLAEL GYQTNFHQAI NDAHQITLCL LSTNCVLDPV IYCFLTKKFR 
KHLSEKFYSM RSSRKCSRAT SDTCTEVIVP ANQTPIVSLK N

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ptafr

Associated with

Other Information

A murine platelet-activating factor receptor gene: cloning, chromosomal localization and up-regulation of expression by lipopolysaccharide in peritoneal resident macrophages. PubMed ID: 8670084

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Database document:

PubMed ID: 8670084

PubMed ID: 16141072

PubMed ID: 19468303

PubMed ID: 19144319