Details for: Ptgds

Gene ID: 19215

Symbol: Ptgds

Ensembl ID: ENSMUSG00000015090

Description: prostaglandin D2 synthase (brain)

Associated with

Other Information

Genular Protein ID: 1530661435

Symbol: PTGDS_MOUSE

Name: Prostaglandin-H2 D-isomerase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8922532

Title: Developmental expression of murine Beta-trace in embryos and adult animals suggests a function in maturation and maintenance of blood-tissue barriers.

PubMed ID: 8922532

DOI: 10.1002/(sici)1097-0177(199611)207:3<332::aid-aja10>3.0.co;2-6

PubMed ID: 9892701

Title: Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.

PubMed ID: 9892701

DOI: 10.1073/pnas.96.2.726

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10781097

Title: Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep.

PubMed ID: 10781097

DOI: 10.1073/pnas.090093997

PubMed ID: 11751991

Title: Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice.

PubMed ID: 11751991

DOI: 10.4049/jimmunol.168.1.443

PubMed ID: 12077186

Title: Perineuronal oligodendrocytes protect against neuronal apoptosis through the production of lipocalin-type prostaglandin D synthase in a genetic demyelinating model.

PubMed ID: 12077186

DOI: 10.1523/jneurosci.22-12-04885.2002

PubMed ID: 11105911

Title: Stage and region-specific localization of lipocalin-type prostaglandin D synthase in the adult murine testis and epididymis.

PubMed ID: 11105911

PubMed ID: 10899920

Title: Dexamethasone induces lipocalin-type prostaglandin D synthase gene expression in mouse neuronal cells.

PubMed ID: 10899920

DOI: 10.1046/j.1471-4159.2000.0750460.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23624557

Title: Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.

PubMed ID: 23624557

DOI: 10.1038/ni.2586

PubMed ID: 17715133

Title: NMR solution structure of lipocalin-type prostaglandin D synthase: evidence for partial overlapping of catalytic pocket and retinoic acid-binding pocket within the central cavity.

PubMed ID: 17715133

DOI: 10.1074/jbc.m700123200

PubMed ID: 19546224

Title: Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.

PubMed ID: 19546224

DOI: 10.1074/jbc.m109.018341

PubMed ID: 19833210

Title: Structural analysis of lipocalin-type prostaglandin D synthase complexed with biliverdin by small-angle X-ray scattering and multi-dimensional NMR.

PubMed ID: 19833210

DOI: 10.1016/j.jsb.2009.10.005

Sequence Information:

  • Length: 189
  • Mass: 21066
  • Checksum: C2C0B3E3B5928643
  • Sequence:
  • MAALRMLWMG LVLLGLLGFP QTPAQGHDTV QPNFQQDKFL GRWYSAGLAS NSSWFREKKA 
    VLYMCKTVVA PSTEGGLNLT STFLRKNQCE TKIMVLQPAG APGHYTYSSP HSGSIHSVSV 
    VEANYDEYAL LFSRGTKGPG QDFRMATLYS RTQTLKDELK EKFTTFSKAQ GLTEEDIVFL 
    PQPDKCIQE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.