Genular: Defining Cellular Identity and Function

Details for: Ptgir

Gene ID: 19222

Symbol: Ptgir

Ensembl ID: ENSMUSG00000043017

Description: prostaglandin I receptor (IP)

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Eicosanoid ligand-binding receptors
(R-MMU-391903)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hemostasis
(R-MMU-109582)
Platelet homeostasis
(R-MMU-418346)
Prostacyclin signalling through prostacyclin receptor
(R-MMU-392851)
Prostanoid ligand receptors
(R-MMU-391908)
Signaling by gpcr
(R-MMU-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Cytosol
(GO:0005829)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Inflammatory response
(GO:0006954)
Membrane
(GO:0016020)
Negative regulation of platelet-derived growth factor receptor signaling pathway
(GO:0010642)
Negative regulation of smooth muscle cell proliferation
(GO:0048662)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Prostacyclin receptor activity
(GO:0016501)
Response to lipopolysaccharide
(GO:0032496)
Signal transduction
(GO:0007165)

Other Information

Proteins

Prostacyclin receptor
Q8CC99_MOUSE

Genular Protein ID: 3395540675

Symbol: PI2R_MOUSE

Name: Prostacyclin receptor

UniProtKB Accession Codes:

P43252 Q52KE5

Database IDs:

Citations:

PubMed ID: 7511597

Title: cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla.

PubMed ID: 7511597

DOI: 10.1016/s0021-9258(17)36979-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10446129

Title: The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling.

PubMed ID: 10446129

DOI: 10.1074/jbc.274.34.23707

PubMed ID: 23457445

Title: Molecular analysis of the prostacyclin receptor's interaction with the PDZ1 domain of its adaptor protein PDZK1.

PubMed ID: 23457445

DOI: 10.1371/journal.pone.0053819

Sequence Information:

Length: 415
Mass: 44463
Checksum: 306929582DDDD24C
Sequence:

MMASDGHPGP PSVTPGSPLS AGGREWQGMA GSCWNITYVQ DSVGPATSTL MFVAGVVGNG 
LALGILGARR RSHPSAFAVL VTGLAVTDLL GTCFLSPAVF VAYARNSSLL GLAHGGTMLC 
DTFAFAMTFF GLASTLILFA MAVERCLALS HPYLYAQLDG PRCARFALPS IYAFCCLFCS 
LPLLGLGEHQ QYCPGSWCFI RMRSAQPGGC AFSLAYASLM ALLVTSIFFC NGSVTLSLYH 
MYRQQRRHHG SFVPTSRARE DEVYHLILLA LMTVIMAVCS LPLMIRGFTQ AIAPDSREMG 
DLLAFRFNAF NPILDPWVFI LFRKAVFQRL KFWLCCLCAR SVHGDLQAPL SRPASGRRDP 
PAPTSLQAKE GSWVPLSSWG TGQVAPLTAV PLTGGDGCSV GMPSKSEAIA ACSLC

Genular Protein ID: 324919412

Symbol: Q8CC99_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8CC99

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 212
Mass: 22896
Checksum: 19A41E644A788362
Sequence:

MMASDGHPGP PSVTPGRPLS AGGREWQGMA GSCWNITYVQ DSRRHHGSFV PTSRAREDEV 
YHLILLALMT VIMAVCSLPL MIRGFTQAIA PDSREMGDLL AFRFNAFNPI LDPWVFILFR 
KAVFQRLKFW LCCLCARSVH GDLQAPLSRP ASGRRDPPAP TSLQAKEGSW VPLSSWGTGQ 
VAPLTAVPLT GGDGCSVGMP SKSEAIAACS LC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ptgir

Associated with

Other Information

cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla. PubMed ID: 7511597

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling. PubMed ID: 10446129

Molecular analysis of the prostacyclin receptor's interaction with the PDZ1 domain of its adaptor protein PDZK1. PubMed ID: 23457445

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073