Details for: Ptn

Gene ID: 19242

Symbol: Ptn

Ensembl ID: ENSMUSG00000029838

Description: pleiotrophin

Associated with

Other Information

Genular Protein ID: 4050326572

Symbol: PTN_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1701634

Title: Isolation of mouse and human cDNA clones encoding a protein expressed specifically in osteoblasts and brain tissues.

PubMed ID: 1701634

DOI: 10.1016/s0006-291x(05)81048-4

PubMed ID: 1457042

Title: Genomic organization of the mouse OSF-1 gene.

PubMed ID: 1457042

DOI: 10.1089/dna.1992.11.735

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1550576

Title: Similarity of the genomic structure between the two members in a new family of heparin-binding factors.

PubMed ID: 1550576

DOI: 10.1016/0006-291x(92)90539-w

PubMed ID: 1768439

Title: Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins.

PubMed ID: 1768439

DOI: 10.3109/08977199109000275

PubMed ID: 11414790

Title: Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule.

PubMed ID: 11414790

DOI: 10.1006/mcne.2001.0998

PubMed ID: 12093164

Title: Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice.

PubMed ID: 12093164

DOI: 10.1006/mcne.2002.1104

PubMed ID: 15121180

Title: HB-GAM inhibits proliferation and enhances differentiation of neural stem cells.

PubMed ID: 15121180

DOI: 10.1016/j.mcn.2004.01.018

PubMed ID: 17121547

Title: Female infertility in mice deficient in midkine and pleiotrophin, which form a distinct family of growth factors.

PubMed ID: 17121547

DOI: 10.1111/j.1365-2443.2006.01028.x

PubMed ID: 16619002

Title: Mice doubly deficient in the midkine and pleiotrophin genes exhibit deficits in the expression of beta-tectorin gene and in auditory response.

PubMed ID: 16619002

DOI: 10.1038/labinvest.3700428

PubMed ID: 19442624

Title: Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading.

PubMed ID: 19442624

DOI: 10.1016/j.bone.2009.01.004

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21791434

Title: Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells.

PubMed ID: 21791434

DOI: 10.1182/blood-2010-05-287235

PubMed ID: 25000129

Title: Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice.

PubMed ID: 25000129

DOI: 10.1371/journal.pone.0100597

PubMed ID: 27445335

Title: Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION.

PubMed ID: 27445335

DOI: 10.1074/jbc.m116.742536

PubMed ID: 28657144

Title: Ptn functions downstream of C/EBPbeta to mediate the effects of cAMP on uterine stromal cell differentiation through targeting Hand2 in response to progesterone.

PubMed ID: 28657144

DOI: 10.1002/jcp.26067

PubMed ID: 30497772

Title: Neural Stem Cells Behave as a Functional Niche for the Maturation of Newborn Neurons through the Secretion of PTN.

PubMed ID: 30497772

DOI: 10.1016/j.neuron.2018.10.051

Sequence Information:

  • Length: 168
  • Mass: 18869
  • Checksum: 2127DA167D2DD33D
  • Sequence:
  • MSSQQYQQQR RKFAAAFLAL IFILAAVDTA EAGKKEKPEK KVKKSDCGEW QWSVCVPTSG 
    DCGLGTREGT RTGAECKQTM KTQRCKIPCN WKKQFGAECK YQFQAWGECD LNTALKTRTG 
    SLKRALHNAD CQKTVTISKP CGKLTKPKPQ AESKKKKKEG KKQEKMLD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.