Details for: Ptpn11
Associated with
Other Information
Genular Protein ID: 3198873401
Symbol: PTN11_MOUSE
Name: Tyrosine-protein phosphatase non-receptor type 11
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8810330
Title: Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule.
PubMed ID: 8810330
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8096088
Title: SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases.
PubMed ID: 8096088
PubMed ID: 7681217
Title: Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.
PubMed ID: 7681217
PubMed ID: 8943348
Title: Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.
PubMed ID: 8943348
PubMed ID: 9110989
Title: Interleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2.
PubMed ID: 9110989
PubMed ID: 9062191
Title: A family of proteins that inhibit signalling through tyrosine kinase receptors.
PubMed ID: 9062191
DOI: 10.1038/386181a0
PubMed ID: 9393882
Title: The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
PubMed ID: 9393882
PubMed ID: 9722576
Title: Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules.
PubMed ID: 9722576
PubMed ID: 9528781
Title: SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.
PubMed ID: 9528781
PubMed ID: 10068651
Title: Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.
PubMed ID: 10068651
PubMed ID: 9867848
Title: The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells.
PubMed ID: 9867848
PubMed ID: 10026201
Title: gp49B1 inhibits IgE-initiated mast cell activation through both immunoreceptor tyrosine-based inhibitory motifs, recruitment of src homology 2 domain-containing phosphatase-1, and suppression of early and late calcium mobilization.
PubMed ID: 10026201
PubMed ID: 10521483
Title: Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.
PubMed ID: 10521483
PubMed ID: 10080542
Title: Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells.
PubMed ID: 10080542
DOI: 10.1002/jlb.65.3.372
PubMed ID: 10896938
Title: p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.
PubMed ID: 10896938
PubMed ID: 12181353
Title: The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.
PubMed ID: 12181353
PubMed ID: 14610044
Title: LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation.
PubMed ID: 14610044
DOI: 10.1084/jem.20030232
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 16684964
Title: Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.
PubMed ID: 16684964
PubMed ID: 16885344
Title: ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.
PubMed ID: 16885344
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 18034455
Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
PubMed ID: 18034455
DOI: 10.1021/pr0701254
PubMed ID: 19948503
Title: Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src.
PubMed ID: 19948503
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20526344
Title: An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions.
PubMed ID: 20526344
DOI: 10.1038/ni.1886
PubMed ID: 14967142
Title: Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment.
PubMed ID: 14967142
PubMed ID: 23112346
Title: Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.
PubMed ID: 23112346
PubMed ID: 23374343
Title: Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.
PubMed ID: 23374343
PubMed ID: 29644115
Title: SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity.
PubMed ID: 29644115
PubMed ID: 7521735
Title: Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
PubMed ID: 7521735
Sequence Information:
- Length: 593
- Mass: 68035
- Checksum: 6C71EEEECCF7F159
- Sequence:
MTSRRWFHPN ITGVEAENLL LTRGVDGSFL ARPSKSNPGD FTLSVRRNGA VTHIKIQNTG DYYDLYGGEK FATLAELVQY YMEHHGQLKE KNGDVIELKY PLNCADPTSE RWFHGHLSGK EAEKLLTEKG KHGSFLVRES QSHPGDFVLS VRTGDDKGES NDGKSKVTHV MIRCQELKYD VGGGERFDSL TDLVEHYKKN PMVETLGTVL QLKQPLNTTR INAAEIESRV RELSKLAETT DKVKQGFWEE FETLQQQECK LLYSRKEGQR QENKNKNRYK NILPFDHTRV VLHDGDPNEP VSDYINANII MPEFETKCNN SKPKKSYIAT QGCLQNTVND FWRMVFQENS RVIVMTTKEV ERGKSKCVKY WPDEYALKEY GVMRVRNVKE SAAHDYTLRE LKLSKVGQGN TERTVWQYHF RTWPDHGVPS DPGGVLDFLE EVHHKQESIV DAGPVVVHCS AGIGRTGTFI VIDILIDIIR EKGVDCDIDV PKTIQMVRSQ RSGMVQTEAQ YRFIYMAVQH YIETLQRRIE EEQKSKRKGH EYTNIKYSLV DQTSGDQSPL PPCTPTPPCA EMREDSARVY ENVGLMQQQR SFR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.