Details for: Ptpn4

Gene ID: 19258

Symbol: Ptpn4

Ensembl ID: ENSMUSG00000026384

Description: protein tyrosine phosphatase, non-receptor type 4

Associated with

Other Information

Genular Protein ID: 3914682046

Symbol: PTN4_MOUSE

Name: Tyrosine-protein phosphatase non-receptor type 4

UniProtKB Accession Codes:

Q9WU22 G5E8E7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 4 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 EC 2 EMBL 4 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 9 Gene3D 4 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 20 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 2 PRO 1 PROSITE 7 PROSITE-ProRule 4 PaxDb 1 PeptideAtlas 1 Pfam 6 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 3 SAM 1 SMART 6 SMR 1 STRING 1 SUPFAM 5 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 11054567

Title: Molecular cloning and characterization of a protein tyrosine phosphatase enriched in testis, a putative murine homologue of human PTPMEG.

PubMed ID: 11054567

DOI: 10.1016/s0378-1119(00)00351-6

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 17953619

Title: Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.

PubMed ID: 17953619

DOI: 10.1111/j.1460-9568.2007.05829.x

PubMed ID: 18614237

Title: The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions.

PubMed ID: 18614237

DOI: 10.1016/j.molimm.2008.05.023

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25825441

Title: Phosphatase PTPN4 preferentially inhibits TRIF-dependent TLR4 pathway by dephosphorylating TRAM.

PubMed ID: 25825441

DOI: 10.4049/jimmunol.1402183

Sequence Information:

  • Length: 926
  • Mass: 105832
  • Checksum: 73E465D804C9C5FB
  • Sequence:
    • MTARFRLPAG RTYNVRASEL ARDRQHTEVV CNILLLDNTV QAFRVNKHDQ GQVLLDIVFK 
HLDLTERDYF GLQLADDSTD NPRWLDPNKP IRKQLKRGSP YNLNFRVKFF VSDPNKLQEE 
YTRYQYFLQI KQDILTGRLS CPCNTAALLA SFAVQSELGD YNQSENLAGY LSDYSFIPNQ 
PQDFEKEIAK LHQQHVGLSP AEAEFNYLNA ARTLELYGVE FHYARDQSNN EILIGVMSGG 
ILIYKNRVRM NTFLWLKIVK ISFKCKQFFI QLRKELHESR ETLLGFNMVN YRACKTLWKA 
CVEHHTFFRL DRPLPPQKNF FAHYFTLGSK FRYCGRTEVQ SVQYGKEKAN KDRVFARSPS 
KPLARKLMDW EVVSRNSLSD DRLETQSLPS RSPPGTPNHR NSSFTQEATR VRPSSVGHLV 
DHVVHMSPSE DFVSQRSPSS TQANSIVLES SPSQETPEDG QPPALPPKQS KKNSWNQIHF 
SNSQQDLVTH TNESFDVPSS PEKSTPNGGI PHDNLVLIKM KPDENGRFGF NVKGGYDQKM 
PVIVSRVAPG TPADLCVPRL NEGDQVVLIN GRDIAEHTHD QVVLFIKASC EKHSGELVLL 
VRPNAVYDVV EEKLESEPDF QYIPEKAPLD SVHQDDHSLR ESMIQLAEGL ITGTVLAQFD 
QLYRKKPGMT MSCAKLPQNI SKNRYRDISP YDATRVLLKG NEDYINANYI NMEIPSSSII 
NQYIACQGPL PHTCKDFWQM TWEQGSSMVV MLTTQVERGR VKCHQYWPEP SESSSYGCYQ 
VTCHSEEGNP AYIFRKMTLF NQEKNESRQL TQIQYTAWPD HGVPDDSSDF LDFVCHVRDQ 
RAGKEEPIIV HCSAGIGRTG VLITMETAMC LIECNQPVYP LDIVRTMRDQ RAMMIQTPSQ 
YRFVCEAILK VYEEGFVKPL TTSSNK

Genular Protein ID: 2271781766

Symbol: Q8BQQ4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BQQ4

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 3 Genevisible 1 Google 1 InterPro 15 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 6 Pfam 4 RefSeq 1 SAM 1 SMART 3 SUPFAM 4

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 556
  • Mass: 63649
  • Checksum: EA22106B95F6D006
  • Sequence:
    • MTARFRLPAG RTYNVRASEL ARDRQHTEVV CNILLLDNTV QAFRVNKHDQ GQVLLDIVFK 
HLDLTERDYF GLQLADDSTD NPRWLDPNKP IRKQLKRGSP YNLNFRVKFF VSDPNKLQEE 
YTRYQYFLQI KQDILTGRLS CPCNTAALLA SFAVQSELGD YNQSENLAGY LSDYSFIPNQ 
PQDFEKEIAK LHQQHVGLSP AEAEFNYLNA ARTLELYGVE FHYARDQSNN EILIGVMSGG 
ILIYKNRVRM NTFLWLKIVK ISFKCKQFFI QLRKELHESR ETLLGFNMVN YRACKTLWKA 
CVEHHTFFRL DRPLPPQKNF FAHYFTLGSK FRYCGRTEVQ SVQYGKEKAN KDRVFARSPS 
KPLARKLMDW EVVSRNSLSD DRLETQSLPS RSPPGTPNHR NSSFTQEATR VRPSSVGHLV 
DHVVHMSPSE DFVSQRCPSS TQANSIVLES SPSQETPEDG QPPALPPKQS KKNSWNQIHF 
SNSQQDLVTH TNESFDVPSS PEKSTPNGGI PHDNLVLIKM KPDENGRFGF NVKGGYDQKM 
PVIVSRVAPG TPLSEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.