Ptprs | ENSMUSG00000013236 | NCBI 19280

Details for: Ptprs

Gene ID: 19280

Symbol: Ptprs

Ensembl ID: ENSMUSG00000013236

Description: protein tyrosine phosphatase receptor type S

Associated with

Neuronal system
(R-MMU-112316)
Protein-protein interactions at synapses
(R-MMU-6794362)
Receptor-type tyrosine-protein phosphatases
(R-MMU-388844)
Synaptic adhesion-like molecules
(R-MMU-8849932)
Cell adhesion
(GO:0007155)
Cell projection
(GO:0042995)
Cerebellum development
(GO:0021549)
Cerebral cortex development
(GO:0021987)
Chondroitin sulfate binding
(GO:0035374)
Corpus callosum development
(GO:0022038)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Dephosphorylation
(GO:0016311)
Establishment of endothelial intestinal barrier
(GO:0090557)
Glutamatergic synapse
(GO:0098978)
Heparin binding
(GO:0008201)
Hippocampus development
(GO:0021766)
Hydrolase activity
(GO:0016787)
Membrane
(GO:0016020)
Modulation of chemical synaptic transmission
(GO:0050804)
Negative regulation of axon extension
(GO:0030517)
Negative regulation of axon regeneration
(GO:0048681)
Negative regulation of collateral sprouting
(GO:0048671)
Negative regulation of dendritic spine development
(GO:0061000)
Negative regulation of interferon-alpha production
(GO:0032687)
Negative regulation of interferon-beta production
(GO:0032688)
Negative regulation of neuron projection development
(GO:0010977)
Negative regulation of toll-like receptor 9 signaling pathway
(GO:0034164)
Neuron projection
(GO:0043005)
Peptidyl-tyrosine dephosphorylation
(GO:0035335)
Phosphatase activity
(GO:0016791)
Phosphoprotein phosphatase activity
(GO:0004721)
Plasma membrane
(GO:0005886)
Postsynaptic density membrane
(GO:0098839)
Presynapse assembly
(GO:0099054)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Protein dephosphorylation
(GO:0006470)
Protein tyrosine phosphatase activity
(GO:0004725)
Regulation of postsynaptic density assembly
(GO:0099151)
Schaffer collateral - ca1 synapse
(GO:0098685)
Spinal cord development
(GO:0021510)
Synapse
(GO:0045202)
Synapse organization
(GO:0050808)
Synaptic membrane adhesion
(GO:0099560)
Synaptic vesicle membrane
(GO:0030672)
Trans-synaptic signaling
(GO:0099537)

Other Information

Proteins

Receptor-type tyrosine-protein phosphatase S
Q3TQ52_MOUSE

Genular Protein ID: 2848193302

Symbol: PTPRS_MOUSE

Name: Receptor-type tyrosine-protein phosphatase S

UniProtKB Accession Codes:

B0V2N1 Q3TEC3 Q3TXC9 Q4JFC7 Q5XJV4 Q64503 Q64699 Q7TT17

Database IDs:

Citations:

PubMed ID: 7529177

Title: Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase.

PubMed ID: 7529177

DOI: 10.1111/j.1432-1033.1994.00773.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10080191

Title: Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma.

PubMed ID: 10080191

DOI: 10.1038/6859

PubMed ID: 15797710

Title: Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS.

PubMed ID: 15797710

DOI: 10.1016/j.mcn.2004.10.011

PubMed ID: 19833921

Title: PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration.

PubMed ID: 19833921

DOI: 10.1126/science.1178310

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19780196

Title: Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice.

PubMed ID: 19780196

DOI: 10.1002/glia.20934

PubMed ID: 21454754

Title: Proteoglycan-specific molecular switch for RPTPsigma clustering and neuronal extension.

PubMed ID: 21454754

DOI: 10.1126/science.1200840

PubMed ID: 22519304

Title: Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity.

PubMed ID: 22519304

DOI: 10.1111/j.1471-4159.2012.07762.x

PubMed ID: 22406547

Title: NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.

PubMed ID: 22406547

DOI: 10.1038/nn.3070

PubMed ID: 25385546

Title: Structural basis for extracellular cis and trans RPTPsigma signal competition in synaptogenesis.

PubMed ID: 25385546

DOI: 10.1038/ncomms6209

PubMed ID: 26231120

Title: Protein tyrosine phosphatase PTPRS is an inhibitory receptor on human and murine plasmacytoid dendritic cells.

PubMed ID: 26231120

DOI: 10.1016/j.immuni.2015.07.009

PubMed ID: 22027896

Title: Structural insights into the homology and differences between mouse protein tyrosine phosphatase-sigma and human protein tyrosine phosphatase-sigma.

PubMed ID: 22027896

DOI: 10.1093/abbs/gmr095

Sequence Information:

Length: 1907
Mass: 211904
Checksum: 725C016196E22D1A
Sequence:

MAPTWSPSVV SVVGPVGLFL VLLARGCLAE EPPRFIREPK DQIGVSGGVA SFVCQATGDP 
KPRVTWNKKG KKVNSQRFET IDFDESSGAV LRIQPLRTPR DENVYECVAQ NSVGEITIHA 
KLTVLREDQL PPGFPNIDMG PQLKVVERTR TATMLCAASG NPDPEITWFK DFLPVDPSAS 
NGRIKQLRSG ALQIESSEET DQGKYECVAT NSAGVRYSSP ANLYVRVRRV APRFSILPMS 
HEIMPGGNVN ITCVAVGSPM PYVKWMQGAE DLTPEDDMPV GRNVLELTDV KDSANYTCVA 
MSSLGVIEAV AQITVKSLPK APGTPVVTEN TATSITVTWD SGNPDPVSYY VIEYKSKSQD 
GPYQIKEDIT TTRYSIGGLS PNSEYEIWVS AVNSIGQGPP SESVVTRTGE QAPASAPRNV 
QARMLSATTM IVQWEEPVEP NGLIRGYRVY YTMEPEHPVG NWQKHNVDDS LLTTVGSLLE 
DETYTVRVLA FTSVGDGPLS DPIQVKTQQG VPGQPMNLRA EAKSETSIGL SWSAPRQESV 
IKYELLFREG DRGREVGRTF DPTTAFVVED LKPNTEYAFR LAARSPQGLG AFTAVVRQRT 
LQAKPSAPPQ DVKCTSLRST AILVSWRPPP PETHNGALVG YSVRYRPLGS EDPDPKEVNN 
IPPTTTQILL EALEKWTEYR VTAVAYTEVG PGPESSPVVV RTDEDVPSAP PRKVEAEALN 
ATAIRVLWRS PTPGRQHGQI RGYQVHYVRM EGAEARGPPR IKDIMLADAQ EMVITNLQPE 
TAYSITVAAY TMKGDGARSK PKVVVTKGAV LGRPTLSVQQ TPEGSLLARW EPPADAAEDP 
VLGYRLQFGR EDAAPATLEL AAWERRFAAP AHKGATYVFR LAARGRAGLG EEAAAALSIP 
EDAPRGFPQI LGAAGNVSAG SVLLRWLPPV PAERNGAIIK YTVSVREAGA PGPATETELA 
AAAQPGAETA LTLRGLRPET AYELRVRAHT RRGPGPFSPP LRYRLARDPV SPKNFKVKMI 
MKTSVLLSWE FPDNYNSPTP YKIQYNGLTL DVDGRTTKKL ITHLKPHTFY NFVLTNRGSS 
LGGLQQTVTA RTAFNMLSGK PSVAPKPDND GFIVVYLPDG QSPVTVQNYF IVMVPLRKSR 
GGQFPVLLGS PEDMDLEELI QDISRLQRRS LRHSRQLEVP RPYIAARFSI LPAVFHPGNQ 
KQYGGFDNRG LEPGHRYVLF VLAVLQKNEP TFAASPFSDP FQLDNPDPQP IVDGEEGLIW 
VIGPVLAVVF IICIVIAILL YKNKPDSKRK DSEPRTKCLL NNADLAPHHP KDPVEMRRIN 
FQTPGMLSHP PIPITDMAEH MERLKANDSL KLSQEYESID PGQQFTWEHS NLEANKPKNR 
YANVIAYDHS RVILQPLEGI MGSDYINANY VDGYRRQNAY IATQGPLPET FGDFWRMVWE 
QRSATVVMMT RLEEKSRIKC DQYWPNRGTE TYGFIQVTLL DTMELATFCV RTFSLHKNGS 
SEKREVRHFQ FTAWPDHGVP EYPTPFLAFL RRVKTCNPPD AGPIVVHCSA GVGRTGCFIV 
IDAMLERIKT EKTVDVYGHV TLMRSQRNYM VQTEDQYGFI HEALLEAVGC GNTEVPARSL 
YTYIQKLAQV EPGEHVTGME LEFKRLASSK AHTSRFITAS LPCNKFKNRL VNILPYESSR 
VCLQPIRGVE GSDYINASFI DGYRQQKAYI ATQGPLAETT EDFWRALWEN NSTIVVMLTK 
LREMGREKCH QYWPAERSAR YQYFVVDPMA EYNMPQYILR EFKVTDARDG QSRTVRQFQF 
TDWPEQGAPK SGEGFIDFIG QVHKTKEQFG QDGPISVHCS AGVGRTGVFI TLSIVLERMR 
YEGVVDIFQT VKVLRTQRPA MVQTEDEYQF CFQAALEYLG SFDHYAT

Genular Protein ID: 2909049263

Symbol: Q3TQ52_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TQ52

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 248
Mass: 27517
Checksum: A8749AAC498E741B
Sequence:

MAPTWSPSVV SVVGPVGLFL VLLARGCLAE EPPRFIREPK DQIGVSGGVA SFVCQATGDP 
KPRVTWNKKG KKVNSQRFET IDFDESSGAV LRIQPLRTPR DENVYECVAQ NSVGEITIHA 
KLTVLREDQL PPGFPNIDMG PQLKVVERTR TATMLCAASG NPDPEITWFK DFLPVDPSAS 
NGRIKQLRSG ALQIESSEET DQGKYECVAT NSAGVRYSSP ANLYVRELRE GWCGFFLFYF 
LYPHFYIL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ptprs

Associated with

Other Information

Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase. PubMed ID: 7529177

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma. PubMed ID: 10080191

Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS. PubMed ID: 15797710

PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. PubMed ID: 19833921

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice. PubMed ID: 19780196

Proteoglycan-specific molecular switch for RPTPsigma clustering and neuronal extension. PubMed ID: 21454754

Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity. PubMed ID: 22519304

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. PubMed ID: 22406547

Structural basis for extracellular cis and trans RPTPsigma signal competition in synaptogenesis. PubMed ID: 25385546

Protein tyrosine phosphatase PTPRS is an inhibitory receptor on human and murine plasmacytoid dendritic cells. PubMed ID: 26231120

Structural insights into the homology and differences between mouse protein tyrosine phosphatase-sigma and human protein tyrosine phosphatase-sigma. PubMed ID: 22027896

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073