Genular: Defining Cellular Identity and Function

Details for: Ptx3

Gene ID: 19288

Symbol: Ptx3

Ensembl ID: ENSMUSG00000027832

Description: pentraxin related gene

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
(1->3)-beta-d-glucan binding
(GO:0001872)
Complement component c1q complex binding
(GO:0001849)
Extracellular matrix
(GO:0031012)
Extracellular matrix organization
(GO:0030198)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Negative regulation by host of viral exo-alpha-sialidase activity
(GO:0044869)
Negative regulation by host of viral glycoprotein metabolic process
(GO:0044871)
Negative regulation by host of viral process
(GO:0044793)
Negative regulation of exo-alpha-sialidase activity
(GO:1903016)
Negative regulation of glycoprotein metabolic process
(GO:1903019)
Negative regulation of viral entry into host cell
(GO:0046597)
Opsonization
(GO:0008228)
Ovarian cumulus expansion
(GO:0001550)
Positive regulation of nitric oxide biosynthetic process
(GO:0045429)
Positive regulation of phagocytosis
(GO:0050766)
Protein binding
(GO:0005515)
Response to yeast
(GO:0001878)
Virion binding
(GO:0046790)

Other Information

Proteins

Pentraxin-related protein PTX3

Genular Protein ID: 4044133460

Symbol: PTX3_MOUSE

Name: Pentraxin-related protein PTX3

UniProtKB Accession Codes:

P48759 Q8VDF1

Database IDs:

Citations:

PubMed ID: 8634434

Title: Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites.

PubMed ID: 8634434

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7592730

Title: Promoter structure and transcriptional activation of the murine TSG-14 gene encoding a tumor necrosis factor/interleukin-1-inducible pentraxin protein.

PubMed ID: 7592730

DOI: 10.1074/jbc.270.43.25584

PubMed ID: 9407058

Title: Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.

PubMed ID: 9407058

DOI: 10.1074/jbc.272.52.32817

PubMed ID: 12763682

Title: Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity.

PubMed ID: 12763682

DOI: 10.1016/s0264-410x(03)00199-3

Sequence Information:

Length: 381
Mass: 41812
Checksum: E3CA3B1D93CFE4EB
Sequence:

MHLPAILLCA LWSAVVAETS DDYELMYVNL DNEIDNGLHP TEDPTPCDCR QEHSEWDKLF 
IMLENSQMRE GMLLQATDDV LRGELQRLRA ELGRLAGGMA RPCAAGGPAD ARLVRALEPL 
LQESRDASLR LARLEDAEAR RPEATVPGLG AVLEELRRTR ADLSAVQSWV ARHWLPAGCE 
TAIFFPMRSK KIFGSVHPVR PMKLESFSTC IWVKATDVLN KTILFSYGTK WNPYEIQLYL 
SSQSLVLVVG GKENKLAADT VVSLGRWSHL CGTWSSEQGS MSLWANGELV ATTVEMAKSH 
SVPEGGLLQI GQEKNGCCVG GGFDESLAFS GRITGFNIWD RVLSEEEIRA SGGVESCHIR 
GNVVGWGVTE IQAHGGAQYV S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ptx3

Associated with

Other Information

Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites. PubMed ID: 8634434

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Promoter structure and transcriptional activation of the murine TSG-14 gene encoding a tumor necrosis factor/interleukin-1-inducible pentraxin protein. PubMed ID: 7592730