Genular: Defining Cellular Identity and Function

Details for: Rab1a

Gene ID: 19324

Symbol: Rab1a

Ensembl ID: ENSMUSG00000020149

Description: RAB1A, member RAS oncogene family

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Copi-dependent golgi-to-er retrograde traffic
(R-MMU-6811434)
Copi-mediated anterograde transport
(R-MMU-6807878)
Copii-mediated vesicle transport
(R-MMU-204005)
Er to golgi anterograde transport
(R-MMU-199977)
Golgi-to-er retrograde transport
(R-MMU-8856688)
Golgi cisternae pericentriolar stack reorganization
(R-MMU-162658)
Intra-golgi and retrograde golgi-to-er traffic
(R-MMU-6811442)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Mitotic prophase
(R-MMU-68875)
M phase
(R-MMU-68886)
Post-translational protein modification
(R-MMU-597592)
Rab gefs exchange gtp for gdp on rabs
(R-MMU-8876198)
Rab geranylgeranylation
(R-MMU-8873719)
Rab regulation of trafficking
(R-MMU-9007101)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Autophagosome assembly
(GO:0000045)
Autophagy
(GO:0006914)
Cell migration
(GO:0016477)
Copii-coated vesicle cargo loading
(GO:0090110)
Cytoplasm
(GO:0005737)
Defense response to bacterium
(GO:0042742)
Early endosome
(GO:0005769)
Endocytosis
(GO:0006897)
Endomembrane system
(GO:0012505)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum to golgi vesicle-mediated transport
(GO:0006888)
Endosome
(GO:0005768)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Golgi organization
(GO:0007030)
G protein activity
(GO:0003925)
Growth hormone secretion
(GO:0030252)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Intracellular protein transport
(GO:0006886)
Melanosome
(GO:0042470)
Melanosome transport
(GO:0032402)
Membrane
(GO:0016020)
Neuronal cell body
(GO:0043025)
Nucleotide binding
(GO:0000166)
Positive regulation of glycoprotein metabolic process
(GO:1903020)
Positive regulation of interleukin-8 production
(GO:0032757)
Presynapse
(GO:0098793)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Substrate adhesion-dependent cell spreading
(GO:0034446)
Synapse
(GO:0045202)
Vesicle-mediated transport
(GO:0016192)
Vesicle transport along microtubule
(GO:0047496)
Virion assembly
(GO:0019068)

Other Information

Proteins

Ras-related protein Rab-1A

Genular Protein ID: 2770792543

Symbol: RAB1A_MOUSE

Name: Ras-related protein Rab-1A

UniProtKB Accession Codes:

P62821 P11476 Q3TX44 Q811M4 Q96N61 Q9Y3T2

Database IDs:

Citations:

PubMed ID: 3127202

Title: The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

PubMed ID: 3127202

DOI: 10.1002/j.1460-2075.1987.tb02750.x

PubMed ID: 2506528

Title: Nucleotide sequence of the mouse ypt1 gene encoding a ras-related GTP-binding protein.

PubMed ID: 2506528

DOI: 10.1093/nar/17.16.6737

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19603039

Title: Rab GTPases as coordinators of vesicle traffic.

PubMed ID: 19603039

DOI: 10.1038/nrm2728

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20639577

Title: Regulation of integrin beta 1 recycling to lipid rafts by Rab1a to promote cell migration.

PubMed ID: 20639577

DOI: 10.1074/jbc.m110.141440

PubMed ID: 22854043

Title: Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes.

PubMed ID: 22854043

DOI: 10.1242/jcs.109314

PubMed ID: 24549040

Title: C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking.

PubMed ID: 24549040

DOI: 10.1093/hmg/ddu068

Sequence Information:

Length: 205
Mass: 22678
Checksum: B2A8F4E3B0FB17D6
Sequence:

MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI 
KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDVTDQESFN NVKQWLQEID RYASENVNKL 
LVGNKCDLTT KKVVDYTTAK EFADSLGIPF LETSAKNATN VEQSFMTMAA EIKKRMGPGA 
TAGGAEKSNV KIQSTPVKQS GGGCC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rab1a

Associated with

Other Information

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene. PubMed ID: 3127202

Nucleotide sequence of the mouse ypt1 gene encoding a ras-related GTP-binding protein. PubMed ID: 2506528

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Rab GTPases as coordinators of vesicle traffic. PubMed ID: 19603039

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Regulation of integrin beta 1 recycling to lipid rafts by Rab1a to promote cell migration. PubMed ID: 20639577

Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes. PubMed ID: 22854043

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. PubMed ID: 24549040