Genular: Defining Cellular Identity and Function

Details for: Rab17

Gene ID: 19329

Symbol: Rab17

Ensembl ID: ENSMUSG00000026304

Description: RAB17, member RAS oncogene family

Associated with

Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Rab geranylgeranylation
(R-MMU-8873719)
Apical plasma membrane
(GO:0016324)
Basolateral plasma membrane
(GO:0016323)
Cell projection
(GO:0042995)
Cilium assembly
(GO:0060271)
Dendrite
(GO:0030425)
Early endosome
(GO:0005769)
Endocytic recycling
(GO:0032456)
Endocytic vesicle
(GO:0030139)
Endocytosis
(GO:0006897)
Endomembrane system
(GO:0012505)
Endosome
(GO:0005768)
Establishment of melanosome localization
(GO:0032401)
Filopodium assembly
(GO:0046847)
Gdp binding
(GO:0019003)
Glutamatergic synapse
(GO:0098978)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
(GO:0002415)
Intracellular protein transport
(GO:0006886)
Melanosome
(GO:0042470)
Melanosome transport
(GO:0032402)
Membrane
(GO:0016020)
Neuronal cell body
(GO:0043025)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Postsynapse
(GO:0098794)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Recycling endosome
(GO:0055037)
Recycling endosome membrane
(GO:0055038)
Regulation of dendrite development
(GO:0050773)
Regulation of endocytosis
(GO:0030100)
Regulation of filopodium assembly
(GO:0051489)
Regulation of synapse assembly
(GO:0051963)
Transcytosis
(GO:0045056)

Other Information

Proteins

Ras-related protein Rab-17

Genular Protein ID: 1893415025

Symbol: RAB17_MOUSE

Name: Ras-related protein Rab-17

UniProtKB Accession Codes:

P35292 Q921D2 Q9D723

Database IDs:

Citations:

PubMed ID: 8486736

Title: Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization.

PubMed ID: 8486736

DOI: 10.1083/jcb.121.3.553

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1555775

Title: The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach.

PubMed ID: 1555775

DOI: 10.1016/0378-1119(92)90387-5

PubMed ID: 9624171

Title: Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells.

PubMed ID: 9624171

DOI: 10.1074/jbc.273.25.15734

PubMed ID: 9490718

Title: Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells.

PubMed ID: 9490718

DOI: 10.1083/jcb.140.5.1039

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21291502

Title: The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking.

PubMed ID: 21291502

DOI: 10.1111/j.1600-0854.2011.01172.x

PubMed ID: 22291024

Title: Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons.

PubMed ID: 22291024

DOI: 10.1074/jbc.m111.314385

Sequence Information:

Length: 214
Mass: 23640
Checksum: 11052D3EC730EFAB
Sequence:

MAQAAGLPQA STASGQPYVS KLVLLGSSSV GKTSLALRYM KQDFSNVLPT VGCAFFTKVL 
DLGSSSLKLE IWDTAGQEKY QSVCHLYFRG ANAALLVYDI TRKDSFHKAQ QWLEDLEKEF 
QPGEVVVMLV GNKTDLGEER EVTFQEGKEF AESKSLLFME TSAKLNYQVS EIFNTVAQEL 
LQRAGDTGSS RPQEGEAVAL NQEPPIRQRQ CCAR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rab17

Associated with

Other Information

Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization. PubMed ID: 8486736

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. PubMed ID: 1555775

Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells. PubMed ID: 9624171

Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. PubMed ID: 9490718

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. PubMed ID: 21291502

Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons. PubMed ID: 22291024