Genular: Defining Cellular Identity and Function

Details for: Rab4a

Gene ID: 19341

Symbol: Rab4a

Ensembl ID: ENSMUSG00000019478

Description: RAB4A, member RAS oncogene family

Associated with

Membrane trafficking
(R-MMU-199991)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of proteins
(R-MMU-392499)
Met receptor recycling
(R-MMU-8875656)
Phospholipid metabolism
(R-MMU-1483257)
Pi metabolism
(R-MMU-1483255)
Post-translational protein modification
(R-MMU-597592)
Rab geranylgeranylation
(R-MMU-8873719)
Rab regulation of trafficking
(R-MMU-9007101)
Signaling by met
(R-MMU-6806834)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Synthesis of pips at the plasma membrane
(R-MMU-1660499)
Tbc/rabgaps
(R-MMU-8854214)
Antigen processing and presentation
(GO:0019882)
Atpase activator activity
(GO:0001671)
Atpase binding
(GO:0051117)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle membrane
(GO:0030659)
Endosome
(GO:0005768)
Extracellular exosome
(GO:0070062)
Gdp binding
(GO:0019003)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Insulin-responsive compartment
(GO:0032593)
Ionotropic glutamate receptor binding
(GO:0035255)
Membrane
(GO:0016020)
Nucleotide binding
(GO:0000166)
Perinuclear region of cytoplasm
(GO:0048471)
Postsynaptic recycling endosome
(GO:0098837)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Rab protein signal transduction
(GO:0032482)
Recycling endosome
(GO:0055037)
Regulation of endocytosis
(GO:0030100)
Small gtpase-mediated signal transduction
(GO:0007264)
Synaptic vesicle membrane
(GO:0030672)
Syntaxin binding
(GO:0019905)
Vesicle
(GO:0031982)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

Ras-related protein Rab-4A
Q3ULK1_MOUSE

Genular Protein ID: 4167160218

Symbol: RAB4A_MOUSE

Name: Ras-related protein Rab-4A

UniProtKB Accession Codes:

P56371 Q3TSQ6

Database IDs:

Citations:

PubMed ID: 8950022

Title: Isolation and sequence determination of cDNA encoding mouse rab 4 and candidate approach for the beige mutation in mice.

PubMed ID: 8950022

DOI: 10.1080/15216549600201243

PubMed ID: 16923123

Title: Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.

PubMed ID: 16923123

DOI: 10.1111/j.1365-2443.2006.00997.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 11172003

Title: A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.

PubMed ID: 11172003

DOI: 10.1073/pnas.98.4.1637

PubMed ID: 14697203

Title: Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release.

PubMed ID: 14697203

DOI: 10.1016/s0092-8674(03)01014-6

PubMed ID: 17509819

Title: Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.

PubMed ID: 17509819

DOI: 10.1016/j.ygeno.2007.03.013

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20048159

Title: Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9.

PubMed ID: 20048159

DOI: 10.1074/jbc.m109.069088

PubMed ID: 20098723

Title: Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.

PubMed ID: 20098723

DOI: 10.1371/journal.pbio.1000283

Sequence Information:

Length: 218
Mass: 24409
Checksum: E471820A506CDA01
Sequence:

MAQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK 
YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV 
LILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFMQC ARKILNKIES 
GELDPERMGS GIQYGDAALR QLRSPRRTQA PSAQECGC

Genular Protein ID: 1054739734

Symbol: Q3ULK1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3ULK1

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 218
Mass: 24337
Checksum: 145214CBE68CDA02
Sequence:

MAQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK 
YVKLQIWDTA GQGRFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV 
LILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFMQC ARKILNKIES 
GELDPERMGS GIQYGDAALR QLRSPRRTQA PSAQECGC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rab4a

Associated with

Other Information

Isolation and sequence determination of cDNA encoding mouse rab 4 and candidate approach for the beige mutation in mice. PubMed ID: 8950022

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity. PubMed ID: 16923123

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic. PubMed ID: 11172003

Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. PubMed ID: 14697203

Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. PubMed ID: 17509819

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9. PubMed ID: 20048159

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PubMed ID: 20098723

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073