Genular: Defining Cellular Identity and Function

Details for: Rab6a

Gene ID: 19346

Symbol: Rab6a

Ensembl ID: ENSMUSG00000030704

Description: RAB6A, member RAS oncogene family

Associated with

Copi-independent golgi-to-er retrograde traffic
(R-MMU-6811436)
Golgi-to-er retrograde transport
(R-MMU-8856688)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Intra-golgi and retrograde golgi-to-er traffic
(R-MMU-6811442)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
Post-translational protein modification
(R-MMU-597592)
Rab gefs exchange gtp for gdp on rabs
(R-MMU-8876198)
Rab geranylgeranylation
(R-MMU-8873719)
Rab regulation of trafficking
(R-MMU-9007101)
Retrograde transport at the trans-golgi-network
(R-MMU-6811440)
Tbc/rabgaps
(R-MMU-8854214)
Acrosomal membrane
(GO:0002080)
Antigen processing and presentation
(GO:0019882)
Atpase activator activity
(GO:0001671)
Atpase binding
(GO:0051117)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Early endosome to golgi transport
(GO:0034498)
Endomembrane system
(GO:0012505)
Endosome to plasma membrane transport vesicle
(GO:0070381)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Intra-golgi vesicle-mediated transport
(GO:0006891)
Intracellular protein transport
(GO:0006886)
Localization
(GO:0051179)
Membrane
(GO:0016020)
Myosin v binding
(GO:0031489)
Nucleotide binding
(GO:0000166)
Peptidyl-cysteine methylation
(GO:0018125)
Presynapse
(GO:0098793)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein localization to golgi apparatus
(GO:0034067)
Protein localization to golgi membrane
(GO:1903292)
Protein transport
(GO:0015031)
Retrograde transport, endosome to golgi
(GO:0042147)
Retrograde vesicle-mediated transport, golgi to endoplasmic reticulum
(GO:0006890)
Trans-golgi network
(GO:0005802)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

Ras-related protein Rab-6A
Q3U4W5_MOUSE

Genular Protein ID: 3690337390

Symbol: RAB6A_MOUSE

Name: Ras-related protein Rab-6A

UniProtKB Accession Codes:

P35279 Q542M6 Q8R2Z7 Q8VEE5 Q9JJD4

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1555775

Title: The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach.

PubMed ID: 1555775

DOI: 10.1016/0378-1119(92)90387-5

PubMed ID: 9438855

Title: Interaction of a Golgi-associated kinesin-like protein with Rab6.

PubMed ID: 9438855

DOI: 10.1126/science.279.5350.580

PubMed ID: 18997784

Title: Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin.

PubMed ID: 18997784

DOI: 10.1038/ng.252

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20643351

Title: Pitchfork regulates primary cilia disassembly and left-right asymmetry.

PubMed ID: 20643351

DOI: 10.1016/j.devcel.2010.06.005

PubMed ID: 20360680

Title: Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.

PubMed ID: 20360680

DOI: 10.1038/emboj.2010.51

PubMed ID: 23737971

Title: A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6.

PubMed ID: 23737971

DOI: 10.1371/journal.pone.0064149

PubMed ID: 31218450

Title: Vps13b is required for acrosome biogenesis through functions in Golgi dynamic and membrane trafficking.

PubMed ID: 31218450

DOI: 10.1007/s00018-019-03192-4

Sequence Information:

Length: 208
Mass: 23590
Checksum: DD08CC2914668FD4
Sequence:

MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR 
TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI 
IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST 
QDRSREDMID IKLEKPQEQP VNEGGCSC

Genular Protein ID: 260671694

Symbol: Q3U4W5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3U4W5

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 208
Mass: 23546
Checksum: CBE04CA13D0A48C1
Sequence:

MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR 
TIRLQLWDTA GQERFRSLIP SYIRDSAAAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI 
IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST 
QDRSREDMID IKLEKPQEQP VNEGGCSC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rab6a

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. PubMed ID: 1555775

Interaction of a Golgi-associated kinesin-like protein with Rab6. PubMed ID: 9438855

Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin. PubMed ID: 18997784

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Pitchfork regulates primary cilia disassembly and left-right asymmetry. PubMed ID: 20643351

Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. PubMed ID: 20360680

A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6. PubMed ID: 23737971

Vps13b is required for acrosome biogenesis through functions in Golgi dynamic and membrane trafficking. PubMed ID: 31218450

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073