Details for: Rac1

Gene ID: 19353

Symbol: Rac1

Ensembl ID: ENSMUSG00000001847

Description: Rac family small GTPase 1

Associated with

Other Information

Genular Protein ID: 691342008

Symbol: RAC1_MOUSE

Name: p21-Rac1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1905006

Title: The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments.

PubMed ID: 1905006

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9707409

Title: The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways.

PubMed ID: 9707409

DOI: 10.1016/s0960-9822(07)00376-4

PubMed ID: 10934474

Title: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.

PubMed ID: 10934474

DOI: 10.1038/35019573

PubMed ID: 10934475

Title: A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity.

PubMed ID: 10934475

DOI: 10.1038/35019582

PubMed ID: 10679324

Title: Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly.

PubMed ID: 10679324

DOI: 10.1016/s0960-9822(00)00315-8

PubMed ID: 12695502

Title: Synapse formation is regulated by the signaling adaptor GIT1.

PubMed ID: 12695502

DOI: 10.1083/jcb.200211002

PubMed ID: 14634666

Title: Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

PubMed ID: 14634666

DOI: 10.1038/ncb1071

PubMed ID: 16002401

Title: Regulation of p21-activated kinase-independent Rac1 signal transduction by Nischarin.

PubMed ID: 16002401

DOI: 10.1074/jbc.m502546200

PubMed ID: 17403031

Title: Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN gamma kinase activation leading to cytoskeleton function and cell migration in astrocytes.

PubMed ID: 17403031

DOI: 10.1111/j.1471-4159.2007.04485.x

PubMed ID: 17116687

Title: Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.

PubMed ID: 17116687

DOI: 10.1128/mcb.00756-06

PubMed ID: 19029984

Title: Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease.

PubMed ID: 19029984

DOI: 10.1038/nm.1879

PubMed ID: 19737524

Title: The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis.

PubMed ID: 19737524

DOI: 10.1016/j.cell.2009.06.047

PubMed ID: 19007770

Title: Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly.

PubMed ID: 19007770

DOI: 10.1016/j.ydbio.2008.10.023

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20696765

Title: Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase.

PubMed ID: 20696765

DOI: 10.1074/jbc.m110.120451

PubMed ID: 20974804

Title: The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells.

PubMed ID: 20974804

DOI: 10.1128/mcb.01001-10

PubMed ID: 22959435

Title: POSH localizes activated Rac1 to control the formation of cytoplasmic dilation of the leading process and neuronal migration.

PubMed ID: 22959435

DOI: 10.1016/j.celrep.2012.08.007

PubMed ID: 23963642

Title: The POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells.

PubMed ID: 23963642

DOI: 10.1002/eji.201343635

PubMed ID: 24352656

Title: Rho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Rac1) GTPase-activating protein that controls dendritic spine morphogenesis.

PubMed ID: 24352656

DOI: 10.1074/jbc.m113.534636

PubMed ID: 26969129

Title: Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.

PubMed ID: 26969129

DOI: 10.1186/s13041-016-0206-6

Sequence Information:

  • Length: 192
  • Mass: 21450
  • Checksum: ACEDF83A45E5EA67
  • Sequence:
  • MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG 
    QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPNTPI ILVGTKLDLR 
    DDKDTIEKLK EKKLTPITYP QGLAMAKEIG AVKYLECSAL TQRGLKTVFD EAIRAVLCPP 
    PVKKRKRKCL LL

Genular Protein ID: 4230736958

Symbol: Q3TLP8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 211
  • Mass: 23432
  • Checksum: 17BCFC04AA646FD1
  • Sequence:
  • MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG 
    QEDYDRLRPL SYPQTVGDTC GKDRPSRGKD KPIADVFLIC FSLVSPASFE NVRAKWYPEV 
    RHHCPNTPII LVGTKLDLRD DKDTIEKLKE KKLTPITYPQ GLAMAKEIGA VKYLECSALT 
    QRGLKTVFDE AIRAVLCPPP VKKRKRKCLL L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.