Genular: Defining Cellular Identity and Function

Details for: Rac2

Gene ID: 19354

Symbol: Rac2

Ensembl ID: ENSMUSG00000033220

Description: Rac family small GTPase 2

Associated with

Beta-catenin independent wnt signaling
(R-MMU-3858494)
Gpvi-mediated activation cascade
(R-MMU-114604)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Intracellular signaling by second messengers
(R-MMU-9006925)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Pcp/ce pathway
(R-MMU-4086400)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Rac2 gtpase cycle
(R-MMU-9013404)
Rho gtpase cycle
(R-MMU-9012999)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate nadph oxidases
(R-MMU-5668599)
Ros and rns production in phagocytes
(R-MMU-1222556)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by wnt
(R-MMU-195721)
Actin cytoskeleton organization
(GO:0030036)
Actin filament
(GO:0005884)
Actin filament organization
(GO:0007015)
Bone resorption
(GO:0045453)
Cell population proliferation
(GO:0008283)
Cell projection assembly
(GO:0030031)
Chemotaxis
(GO:0006935)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Erythrocyte enucleation
(GO:0043131)
G protein-coupled receptor signaling pathway
(GO:0007186)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Lamellipodium
(GO:0030027)
Lymphocyte aggregation
(GO:0071593)
Mast cell proliferation
(GO:0070662)
Membrane
(GO:0016020)
Nuclear envelope
(GO:0005635)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Positive regulation of lamellipodium assembly
(GO:0010592)
Positive regulation of mast cell proliferation
(GO:0070668)
Positive regulation of neutrophil chemotaxis
(GO:0090023)
Protein binding
(GO:0005515)
Protein kinase regulator activity
(GO:0019887)
Regulation of cell-substrate adhesion
(GO:0010810)
Regulation of cell migration
(GO:0030334)
Regulation of mast cell chemotaxis
(GO:0060753)
Regulation of mast cell degranulation
(GO:0043304)
Regulation of neutrophil migration
(GO:1902622)
Regulation of respiratory burst
(GO:0060263)
Regulation of t cell proliferation
(GO:0042129)
Signal transduction
(GO:0007165)
Small gtpase-mediated signal transduction
(GO:0007264)

Other Information

Proteins

Ras-related C3 botulinum toxin substrate 2

Genular Protein ID: 743522528

Symbol: RAC2_MOUSE

Name: Ras-related C3 botulinum toxin substrate 2

UniProtKB Accession Codes:

Q05144 Q3TBC4 Q9D8X9

Database IDs:

Citations:

PubMed ID: 2189110

Title: A member of the ras gene superfamily is expressed specifically in T, B and myeloid hemopoietic cells.

PubMed ID: 2189110

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27084103

Title: POSH regulates CD4+ T cell differentiation and survival.

PubMed ID: 27084103

DOI: 10.4049/jimmunol.1501728

Sequence Information:

Length: 192
Mass: 21441
Checksum: 2A1F1266AB9D7705
Sequence:

MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG 
QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR 
DDKDTIEKLK EKKLAPITYP QGLALAKDID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ 
PTRQQKRPCS LL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rac2

Associated with

Other Information

A member of the ras gene superfamily is expressed specifically in T, B and myeloid hemopoietic cells. PubMed ID: 2189110

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334