Genular: Defining Cellular Identity and Function

Details for: Rad21

Gene ID: 19357

Symbol: Rad21

Ensembl ID: ENSMUSG00000022314

Description: RAD21 cohesin complex component

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cohesin loading onto chromatin
(R-MMU-2470946)
Establishment of sister chromatid cohesion
(R-MMU-2468052)
Metabolism of proteins
(R-MMU-392499)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic telophase/cytokinesis
(R-MMU-68884)
M phase
(R-MMU-68886)
Post-translational protein modification
(R-MMU-597592)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Separation of sister chromatids
(R-MMU-2467813)
S phase
(R-MMU-69242)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Apoptotic process
(GO:0006915)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Chromatin looping
(GO:0140588)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome segregation
(GO:0007059)
Cohesin complex
(GO:0008278)
Condensed nuclear chromosome
(GO:0000794)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor binding
(GO:0140297)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Lncrna binding
(GO:0106222)
Midbody
(GO:0030496)
Mitotic cohesin complex
(GO:0030892)
Multicellular organism development
(GO:0007275)
Negative regulation of g2/m transition of mitotic cell cycle
(GO:0010972)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of glial cell apoptotic process
(GO:0034351)
Negative regulation of interleukin-1 beta production
(GO:0032691)
Negative regulation of mitotic metaphase/anaphase transition
(GO:0045841)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Nuclear matrix
(GO:0016363)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of interleukin-10 production
(GO:0032733)
Positive regulation of sister chromatid cohesion
(GO:0045876)
Protein binding
(GO:0005515)
Protein localization to chromatin
(GO:0071168)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Replication-born double-strand break repair via sister chromatid exchange
(GO:1990414)
Sister chromatid cohesion
(GO:0007062)

Other Information

Proteins

Double-strand-break repair protein rad21 homolog
Q3TG35_MOUSE

Genular Protein ID: 2134537680

Symbol: RAD21_MOUSE

Name: Double-strand-break repair protein rad21 homolog

UniProtKB Accession Codes:

Q61550 P70219 Q3TQ09 Q810A8 Q91VB9 Q9DBU4

Database IDs:

Citations:

PubMed ID: 8521526

Title: cDNA cloning and sequence analysis of a novel calcium binding protein with oligoproline motif.

PubMed ID: 8521526

DOI: 10.1247/csf.20.263

PubMed ID: 8812457

Title: Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse.

PubMed ID: 8812457

DOI: 10.1006/geno.1996.0466

PubMed ID: 11471062

Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.

PubMed ID: 11471062

DOI: 10.1007/s00335-001-1001-x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10375619

Title: Characterization of the components of the putative mammalian sister chromatid cohesion complex.

PubMed ID: 10375619

DOI: 10.1016/s0378-1119(99)00160-2

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 18237772

Title: Cohesins functionally associate with CTCF on mammalian chromosome arms.

PubMed ID: 18237772

DOI: 10.1016/j.cell.2008.01.011

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 635
Mass: 72083
Checksum: 2EC1AC08E358E9CE
Sequence:

MFYAHFVLSK RGPLAKIWLA AHWDKKLTKA HVFECNLESS VESIISPKVK MALRTSGHLL 
LGVVRIYHRK AKYLLADCNE AFIKIKMAFR PGVVDLPEEN REAAYNAITL PEEFHDFDQP 
LPDLDDIDVA QQFSLNQSRV EEITMREEVG NISILQENDF GDFGMDDREI MREGSAFEDD 
DMLVSTSASN LLLEPEQSTS NLNEKMNHLE YEDQYKDDNF GEGNDGGILD DKLISNNDGG 
IFDDPPALSE AGVMLPEQPA HDDMDEDDNG SLGGPDSPDS VDPVEPMPTM TDQTTLVPNE 
EEAFALEPID ITVKETKAKR KRKLIVDSVK ELDSKTIRAQ LSDYSDIVTT LDLAPPTKKL 
MMWKETGGVE KLFFLPAQPL WNNRLLKLFT RCLTPLVPED LRKRRKGGEA DNLDEFLKEF 
ENPEVPREEQ QPQQQQPQPQ RDVIDEPIIE EPSRLQDSVM EASRTTIEES AMPPPPPQGV 
KRKAGQIDPE PSIPPQQVEQ MEIPPVELPP EEPPNICQLI PELELLPEKE KEKEKEKEEE 
EEEEDEDASG GDQDQEERRW NKRTQQMLHG LQRALAKTGA ESISLLELCR NTNRKQAAAK 
FYSFLVLKKQ QAIELTQEEP YSDIIATPGP RFHII

Genular Protein ID: 4281520614

Symbol: Q3TG35_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TG35

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 635
Mass: 72011
Checksum: 2E380DB20158E9CE
Sequence:

MFYAHFVLSK RGPLAKIWLA AHWDKKLTKA HVFECNLESS VESIISPKVK MALRTSGHLL 
LGVVRIYHRK AKYLLADCNE AFIKIKMAFR PGVVDLPEGN REAAYNAITL PEEFHDFDQP 
LPDLDDIDVA QQFSLNQSRV EEITMREEVG NISILQENDF GDFGMDDREI MREGSAFEDD 
DMLVSTSASN LLLEPEQSTS NLNEKMNHLE YEDQYKDDNF GEGNDGGILD DKLISNNDGG 
IFDDPPALSE AGVMLPEQPA HDDMDEDDNG SLGGPDSPDS VDPVEPMPTM TDQTTLVPNE 
EEAFALEPID ITVKETKAKR KRKLIVDSVK ELDSKTIRAQ LSDYSDIVTT LDLAPPTKKL 
MMWKETGGVE KLFFLPAQPL WNNRLLKLFT RCLTPLVPED LRKRRKGGEA DNLDEFLKEF 
ENPEVPREEQ QPQQQQPQPQ RDVIDEPIIE EPSRLQDSVM EASRTTIEES AMPPPPPQGV 
KRKAGQIDPE PSIPPQQVEQ MEIPPVELPP EEPPNICQLI PELELLPEKE KEKEKEKEEE 
EEEEDEDASG GDQDQEERRW NKRTQQMLHG LQRALAKTGA ESISLLELCR NTNRKQAAAK 
FYSFLVLKKQ QAIELTQEEP YSDIIATPGP RFHII

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rad21

Associated with

Other Information

cDNA cloning and sequence analysis of a novel calcium binding protein with oligoproline motif. PubMed ID: 8521526

Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse. PubMed ID: 8812457

High-throughput sequence identification of gene coding variants within alcohol-related QTLs. PubMed ID: 11471062

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the components of the putative mammalian sister chromatid cohesion complex. PubMed ID: 10375619

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

Cohesins functionally associate with CTCF on mammalian chromosome arms. PubMed ID: 18237772

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073