Genular: Defining Cellular Identity and Function

Details for: Rad23b

Gene ID: 19359

Symbol: Rad23b

Ensembl ID: ENSMUSG00000028426

Description: RAD23 homolog B, nucleotide excision repair protein

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Deubiquitination
(R-MMU-5688426)
Dna damage recognition in gg-ner
(R-MMU-5696394)
Formation of incision complex in gg-ner
(R-MMU-5696395)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Josephin domain dubs
(R-MMU-5689877)
Metabolism of proteins
(R-MMU-392499)
N-glycan trimming in the er and calnexin/calreticulin cycle
(R-MMU-532668)
Nucleotide excision repair
(R-MMU-5696398)
Post-translational protein modification
(R-MMU-597592)
Cellular response to interleukin-7
(GO:0098761)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Damaged dna binding
(GO:0003684)
Dna damage response
(GO:0006974)
Dna damage sensor activity
(GO:0140612)
Dna repair
(GO:0006281)
Nucleoplasm
(GO:0005654)
Nucleotide-excision repair
(GO:0006289)
Nucleus
(GO:0005634)
Polyubiquitin modification-dependent protein binding
(GO:0031593)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Proteasome binding
(GO:0070628)
Proteasome complex
(GO:0000502)
Protein binding
(GO:0005515)
Regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032434)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Spermatogenesis
(GO:0007283)
Transcription cis-regulatory region binding
(GO:0000976)
Ubiquitin binding
(GO:0043130)
Xpc complex
(GO:0071942)

Other Information

Proteins

UV excision repair protein RAD23 homolog B
Q3UQN3_MOUSE

Genular Protein ID: 731645960

Symbol: RD23B_MOUSE

Name: UV excision repair protein RAD23 homolog B

UniProtKB Accession Codes:

P54728 Q3TUA4

Database IDs:

Citations:

PubMed ID: 8808275

Title: Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23.

PubMed ID: 8808275

DOI: 10.1006/geno.1996.0004

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11562482

Title: Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation.

PubMed ID: 11562482

DOI: 10.1073/pnas.201393498

PubMed ID: 11809813

Title: Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B.

PubMed ID: 11809813

DOI: 10.1128/mcb.22.4.1233-1245.2002

PubMed ID: 12815074

Title: A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein.

PubMed ID: 12815074

DOI: 10.1101/gad.260003

PubMed ID: 15336624

Title: Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex.

PubMed ID: 15336624

DOI: 10.1016/j.dnarep.2004.06.010

PubMed ID: 15358861

Title: A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins.

PubMed ID: 15358861

DOI: 10.1073/pnas.0405663101

PubMed ID: 16249333

Title: Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome.

PubMed ID: 16249333

DOI: 10.1073/pnas.0507155102

PubMed ID: 16709668

Title: The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor.

PubMed ID: 16709668

DOI: 10.1073/pnas.0602747103

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 16500903

Title: Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.

PubMed ID: 16500903

DOI: 10.1074/jbc.m600137200

Sequence Information:

Length: 416
Mass: 43513
Checksum: 7440E6A9C8ADF454
Sequence:

MQVTLKTLQQ QTFKIDIDPE ETVKALKEKI ESEKGKDAFP VAGQKLIYAG KILSDDTALK 
EYKIDEKNFV VVMVTKPKAV TTAVPATTQP SSTPSPTAVS SSPAVAAAQA PAPTPALPPT 
STPASTAPAS TTASSEPAPA GATQPEKPAE KPAQTPVLTS PAPADSTPGD SSRSNLFEDA 
TSALVTGQSY ENMVTEIMSM GYEREQVIAA LRASFNNPDR AVEYLLMGIP GDRESQAVVD 
PPPQAVSTGT PQSPAVAAAA ATTTATTTTT SGGHPLEFLR NQPQFQQMRQ IIQQNPSLLP 
ALLQQIGREN PQLLQQISQH QEHFIQMLNE PVQEAGSQGG GGGGGGGGGG GGGGGIAEAG 
SGHMNYIQVT PQEKEAIERL KALGFPEGLV IQAYFACEKN ENLAANFLLQ QNFDED

Genular Protein ID: 281702888

Symbol: Q3UQN3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UQN3

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 411
Mass: 43227
Checksum: 1ABDEE33ABC3E521
Sequence:

MQVTLKTLQQ QTFKIDIDPE ETVKALKEKI ESEKGKDAFP VAGQKLIYAG KILSDDTALK 
EYKIDEKNFV VVMVTKPKAV TTAVPATTQP SSTPSPTAVS SSPAVAAAQA PAPTPALPPT 
STPASTAPAS TTASSEPAPA GATQPEKPAE KPAQTPVLTS PAPADSTPGD SSRSNLFEDA 
TSALVTGQSY ENMVTEIMSM GYEREQVIAA LRASFNNPDR AVEYLLMGIP GDRESQAVVD 
PPPQAVSTGT PQSPAVAAAA ATTTATTTTT SGGHPLEFLR NQPQFQQMRQ IIQQNPSLLP 
ALLQQIGREN PQLLQQISQH QEHFIQMLNE PVQEAGSQGG GGGGGGGGGG IAEAGSGHMN 
YIQVTPQEKE AIERLKALGF PEGLVIQAYF ACEKNENLAA NFLLQQNFDE D

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rad23b

Associated with

Other Information

Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23. PubMed ID: 8808275

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation. PubMed ID: 11562482

Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B. PubMed ID: 11809813

A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein. PubMed ID: 12815074

Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex. PubMed ID: 15336624

A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins. PubMed ID: 15358861

Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome. PubMed ID: 16249333

The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor. PubMed ID: 16709668

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways. PubMed ID: 16500903

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073