Details for: Raet1b

Gene ID: 19369

Symbol: Raet1b

Description: retinoic acid early transcript beta

Associated with

  • Antigen processing and presentation of endogenous peptide antigen via mhc class ib
    (GO:0002476)
  • Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway, tap-independent
    (GO:0002486)
  • Cellular response to exogenous dsrna
    (GO:0071360)
  • Cellular response to lipopolysaccharide
    (GO:0071222)
  • Defense response to bacterium
    (GO:0042742)
  • External side of plasma membrane
    (GO:0009897)
  • Extracellular space
    (GO:0005615)
  • Immune response
    (GO:0006955)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Membrane
    (GO:0016020)
  • Natural killer cell lectin-like receptor binding
    (GO:0046703)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of immune response to tumor cell
    (GO:0002839)
  • Positive regulation of macrophage activation
    (GO:0043032)
  • Positive regulation of natural killer cell activation
    (GO:0032816)
  • Positive regulation of nitric oxide biosynthetic process
    (GO:0045429)
  • Positive regulation of t cell mediated cytotoxicity
    (GO:0001916)
  • Positive regulation of type ii interferon production
    (GO:0032729)
  • Protein binding
    (GO:0005515)
  • Side of membrane
    (GO:0098552)
  • Susceptibility to natural killer cell mediated cytotoxicity
    (GO:0042271)

Other Information

Genular Protein ID: 2429111629

Symbol: RAE1B_MOUSE

Name: Retinoic acid early-inducible protein 1-beta

UniProtKB Accession Codes:

O08603 A2RS95

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 4 EvolutionaryTrace 1 GO 18 Gene3D 1 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PDB 4 PDBsum 2 PRO 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 SwissPalm 1 iPTMnet 1

Citations:

PubMed ID: 8882725

Title: Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.

PubMed ID: 8882725

DOI: 10.1093/oxfordjournals.jbchem.a021242

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10894171

Title: Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

PubMed ID: 10894171

DOI: 10.1016/s1074-7613(00)80222-8

PubMed ID: 8982867

Title: Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain.

PubMed ID: 8982867

DOI: 10.1093/oxfordjournals.jbchem.a021517

PubMed ID: 11248803

Title: Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.

PubMed ID: 11248803

DOI: 10.1038/77793

PubMed ID: 11557981

Title: Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity.

PubMed ID: 11557981

DOI: 10.1038/35093109

PubMed ID: 11825567

Title: Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.

PubMed ID: 11825567

DOI: 10.1016/s1074-7613(02)00258-3

Sequence Information:

  • Length: 253
  • Mass: 28625
  • Checksum: 33842B4EF9566867
  • Sequence:
    • MAKAAVTKRH HFMIQKLLIL LSYGYTNGLD DAHSLRCNLT IKDPTPADPL WYEAKCFVGE 
ILILHLSNIN KTMTSGDPGE TANATEVKKC LTQPLKNLCQ KLRNKVSNTK VDTHKTNGYP 
HLQVTMIYPQ SQGRTPSATW EFNISDSYFF TFYTENMSWR SANDESGVIM NKWKDDGEFV 
KQLKFLIHEC SQKMDEFLKQ SKEKPRSTSR SPSITQLTST SPLPPPSHST SKKGFISVGL 
IFISLLFAFA FAM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.