Details for: Rangap1

Gene ID: 19387

Symbol: Rangap1

Ensembl ID: ENSMUSG00000022391

Description: RAN GTPase activating protein 1

Associated with

Other Information

Genular Protein ID: 3947682165

Symbol: RAGP1_MOUSE

Name: Ran GTPase-activating protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8314081

Title: A murine homolog of the yeast RNA1 gene is required for postimplantation development.

PubMed ID: 8314081

DOI: 10.1101/gad.8.3.265

PubMed ID: 7891706

Title: Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.

PubMed ID: 7891706

DOI: 10.1128/mcb.15.4.2117

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9442102

Title: Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association.

PubMed ID: 9442102

DOI: 10.1083/jcb.140.2.259

PubMed ID: 9456312

Title: SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex.

PubMed ID: 9456312

DOI: 10.1083/jcb.140.3.499

PubMed ID: 15037602

Title: RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly.

PubMed ID: 15037602

DOI: 10.1083/jcb.200309126

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 16469311

Title: SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes.

PubMed ID: 16469311

DOI: 10.1016/j.yexcr.2005.12.031

PubMed ID: 18305100

Title: The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import.

PubMed ID: 18305100

DOI: 10.1091/mbc.e07-12-1279

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26304119

Title: MYCBP2 is a guanosine exchange factor for Ran protein and determines its localization in neurons of dorsal root ganglia.

PubMed ID: 26304119

DOI: 10.1074/jbc.m115.646901

PubMed ID: 26506250

Title: The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells.

PubMed ID: 26506250

DOI: 10.1371/journal.pone.0141309

PubMed ID: 31088288

Title: The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease.

PubMed ID: 31088288

DOI: 10.1089/ars.2019.7724

PubMed ID: 11853669

Title: Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1.

PubMed ID: 11853669

DOI: 10.1016/s0092-8674(02)00630-x

Sequence Information:

  • Length: 589
  • Mass: 63531
  • Checksum: 775ADE3A53EFD558
  • Sequence:
  • MASEDIAKLA ETLAKTQVAG GQLSFKGKGL KLNTAEDAKD VIKEIEEFDG LEALRLEGNT 
    VGVEAARVIA KALEKKSELK RCHWSDMFTG RLRSEIPPAL ISLGEGLITA GAQLVELDLS 
    DNAFGPDGVR GFEALLKSPA CFTLQELKLN NCGMGIGGGK ILAAALTECH RKSSAQGKPL 
    ALKVFVAGRN RLENDGATAL AEAFGIIGTL EEVHMPQNGI NHPGVTALAQ AFAINPLLRV 
    INLNDNTFTE KGGVAMAETL KTLRQVEVIN FGDCLVRSKG AVAIADAVRG GLPKLKELNL 
    SFCEIKRDAA LVVAEAVADK AELEKLDLNG NALGEEGCEQ LQEVMDSFNM AKVLASLSDD 
    EGEDEDEEEE GEEDDEEEED EEDEEDDDEE EEEQEEEEEP PQRGSGEEPA TPSRKILDPN 
    SGEPAPVLSS PTPTDLSTFL SFPSPEKLLR LGPKVSVLIV QQTDTSDPEK VVSAFLKVAS 
    VFRDDASVKT AVLDAIDALM KKAFSCSSFN SNTFLTRLLI HMGLLKSEDK IKAIPSLHGP 
    LMVLNHVVRQ DYFPKALAPL LLAFVTKPNG ALETCSFARH NLLQTLYNI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.