Details for: Rasgrf2
Associated with
Other Information
Genular Protein ID: 2368901255
Symbol: RGRF2_MOUSE
Name: Ras-specific guanine nucleotide-releasing factor 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9032266
Title: Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras.
PubMed ID: 9032266
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 11238945
Title: Ras binding triggers ubiquitination of the Ras exchange factor Ras-GRF2.
PubMed ID: 11238945
PubMed ID: 11909944
Title: Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.
PubMed ID: 11909944
PubMed ID: 9707409
Title: The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways.
PubMed ID: 9707409
PubMed ID: 10373510
Title: Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.
PubMed ID: 10373510
PubMed ID: 10733575
Title: Calmodulin-independent coordination of Ras and extracellular signal-regulated kinase activation by Ras-GRF2.
PubMed ID: 10733575
PubMed ID: 11500499
Title: Prenylation of target GTPases contributes to signaling specificity of Ras-guanine nucleotide exchange factors.
PubMed ID: 11500499
PubMed ID: 11856323
Title: Dematin interacts with the Ras-guanine nucleotide exchange factor Ras-GRF2 and modulates mitogen-activated protein kinase pathways.
PubMed ID: 11856323
PubMed ID: 15029245
Title: Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.
PubMed ID: 15029245
PubMed ID: 15128856
Title: p35/cyclin-dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 (RasGRF2) mediates Rac-dependent extracellular signal-regulated kinase 1/2 activity, altering RasGRF2 and microtubule-associated protein 1b distribution in neurons.
PubMed ID: 15128856
PubMed ID: 14749369
Title: Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.
PubMed ID: 14749369
PubMed ID: 16649990
Title: The guanine nucleotide exchange factor RasGRF1 directly binds microtubules via DHPH2-mediated interaction.
PubMed ID: 16649990
PubMed ID: 16407208
Title: Age-dependent participation of Ras-GRF proteins in coupling calcium-permeable AMPA glutamate receptors to Ras/Erk signaling in cortical neurons.
PubMed ID: 16407208
PubMed ID: 16467520
Title: Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.
PubMed ID: 16467520
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1189
- Mass: 135668
- Checksum: 42E346B623F18E59
- Sequence:
MQKSVRYNEG HALYLAMLAR KEGTKRGFLS KKAAEASRWH EKWFALYQNV LFYFEGEQSG RPAGMYLLEG CSCERTPAPP RTNAGPAGAR DALDKQYYFT VLFGHDGQKP LELRCEEEQA GKEWMEAIHQ ASYADILIER EVLMQKYIHL VQIVETEKIA TNQLRHQLED QDTEIERLKS EIVALNKTKE RMRPYHVHQE EEDPDIKKIK KVQSFMRGWL CRRKWKTIVQ DYICSPHAES MRKRNQIVFT MVEAETEYVH QLYILVNGFL RPLRMAASSK KPPINHDDVS SIFLNSETIM FLHEIFHQGL KARLANWPTL VLADLFDILL PMLNIYQEFV RNHQYSLQVL ANCKQNRDFD KLLKQYEANP ACEGRMLETF LTYPMFQIPR YIITLHELLA HTPHEHVERK SLEFAKSKLE ELSRVMHDEV SDTENIRKNL AIERMIVEGC DILLDTSQTF IRQGSLIQVP SVERGKLSKV RLGSLSLKKE GERQCFLFTK HFLICTRSSG GKLHLLKTGG VLSLIQCTLI EEPDGSDDDP KGSGHMFGHL DFKIVVEPPD AASFTVVLLA PSRQEKAAWM SDISQCVDNI RCNGLMTIVF EENSKVTVPH MIKSDARLHK DDTDICFSKT LNSCKVPQIR YASVERLLER LTDLRFLSID FLNTFLHTYR IFTTATVVLA KLSDIYKRPF TSIPVRSLEL FFATSQNNRE HLVDGKSPRL CRKFSSPPPL AVSRTSSPVR ARKLSLTSSL NSRIGALDLT NSSSSSSPTT TTHSPAASPP PHTAVLESAP ADKAGDSADM SPCRSPTTPR HLRYRQPGGQ VADSAHCSVS PASAFAIATA AAGHGSPPGF NNERTCDKEF IIRRTATNRV LNVLRHWVSK HAQDFELNNE LKMNVLNLLE EVLRDPDLLP QERKATANIL RALSQDDQDD IHLKLEDIIQ MTDCPKAECF ETLSAMELAE QITLLDHIVF RSIPYEEFLG QGWMKLDKNE RTPYIMKTSQ HFNEMSNLVA SQIMNYADIS SRANAIEKWV AVADICRCLH NYNGVLEITS ALNRSAIYRL KKTWAKVSKQ TKALMDKLQK TVSSEGRFKN LRETLKNCNP PAVPYLGMYL TDLAFIEEGT PNFTEEGLVN FSKMRMISHI IREIRQFQQT AYRIDQQPKV IQYLLDKALV IDEDSLYELS LKIEPRLPA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.