Genular: Defining Cellular Identity and Function

Details for: Rbbp4

Gene ID: 19646

Symbol: Rbbp4

Ensembl ID: ENSMUSG00000057236

Description: retinoblastoma binding protein 4, chromatin remodeling factor

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Chromatin modifying enzymes
(R-MMU-3247509)
Chromosome maintenance
(R-MMU-73886)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-MMU-606279)
Epigenetic regulation of gene expression
(R-MMU-212165)
G0 and early g1
(R-MMU-1538133)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hdacs deacetylate histones
(R-MMU-3214815)
Intracellular signaling by second messengers
(R-MMU-9006925)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Oxidative stress induced senescence
(R-MMU-2559580)
Pip3 activates akt signaling
(R-MMU-1257604)
Pkmts methylate histone lysines
(R-MMU-3214841)
Prc2 methylates histones and dna
(R-MMU-212300)
Pten regulation
(R-MMU-6807070)
Regulation of pten gene transcription
(R-MMU-8943724)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through acetylation
(R-MMU-6804758)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase i promoter clearance
(R-MMU-73854)
Rna polymerase i transcription
(R-MMU-73864)
Rna polymerase i transcription initiation
(R-MMU-73762)
Signal transduction
(R-MMU-162582)
Transcriptional regulation by e2f6
(R-MMU-8953750)
Transcriptional regulation by tp53
(R-MMU-3700989)
Atp-dependent activity, acting on dna
(GO:0008094)
Atpase complex
(GO:1904949)
Brain development
(GO:0007420)
Caf-1 complex
(GO:0033186)
Cell cycle
(GO:0007049)
Chromatin
(GO:0000785)
Chromatin organization
(GO:0006325)
Chromatin remodeling
(GO:0006338)
Chromosome
(GO:0005694)
Chromosome, telomeric region
(GO:0000781)
Cytosol
(GO:0005829)
Dna replication
(GO:0006260)
Dna replication-dependent chromatin assembly
(GO:0006335)
Esc/e(z) complex
(GO:0035098)
Histone binding
(GO:0042393)
Histone deacetylase binding
(GO:0042826)
Histone deacetylase complex
(GO:0000118)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of stem cell population maintenance
(GO:1902455)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Nucleoplasm
(GO:0005654)
Nucleosome assembly
(GO:0006334)
Nucleus
(GO:0005634)
Nurd complex
(GO:0016581)
Nurf complex
(GO:0016589)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of stem cell population maintenance
(GO:1902459)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Regulation of cell fate specification
(GO:0042659)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of stem cell differentiation
(GO:2000736)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)

Other Information

Proteins

Histone-binding protein RBBP4

Genular Protein ID: 919071168

Symbol: RBBP4_MOUSE

Name: Histone-binding protein RBBP4

UniProtKB Accession Codes:

Q60972 A2A875

Database IDs:

Citations:

PubMed ID: 7503932

Title: Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.

PubMed ID: 7503932

DOI: 10.1074/jbc.270.43.25507

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9702189

Title: SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors.

PubMed ID: 9702189

DOI: 10.1016/s1097-2765(00)80111-2

PubMed ID: 10866654

Title: Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.

PubMed ID: 10866654

DOI: 10.1128/mcb.20.14.4970-4978.2000

PubMed ID: 10984530

Title: Identification of a nuclear domain with deacetylase activity.

PubMed ID: 10984530

DOI: 10.1073/pnas.97.19.10330

PubMed ID: 11788710

Title: Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.

PubMed ID: 11788710

DOI: 10.1093/nar/30.2.475

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 19026780

Title: EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

PubMed ID: 19026780

DOI: 10.1016/j.molcel.2008.10.016

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 28554894

Title: Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

PubMed ID: 28554894

DOI: 10.15252/embj.201696307

PubMed ID: 34180153

Title: PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.

PubMed ID: 34180153

DOI: 10.1002/advs.202102060

Sequence Information:

Length: 425
Mass: 47656
Checksum: B71E2D55A444C360
Sequence:

MADKEAAFDD AVEERVINEE YKIWKKNTPF LYDLVMTHAL EWPSLTAQWL PDVTRPEGKD 
FSIHRLVLGT HTSDEQNHLV IASVQLPNDD AQFDASHYDS EKGEFGGFGS VSGKIEIEIK 
INHEGEVNRA RYMPQNPCII ATKTPSSDVL VFDYTKHPSK PDPSGECNPD LRLRGHQKEG 
YGLSWNPNLS GHLLSASDDH TICLWDISAV PKEGKVVDAK TIFTGHTAVV EDVSWHLLHE 
SLFGSVADDQ KLMIWDTRSN NTSKPSHSVD AHTAEVNCLS FNPYSEFILA TGSADKTVAL 
WDLRNLKLKL HSFESHKDEI FQVQWSPHNE TILASSGTDR RLNVWDLSKI GEEQSPEDAE 
DGPPELLFIH GGHTAKISDF SWNPNEPWVI CSVSEDNIMQ VWQMAENIYN DEDPEGSVDP 
EGQGS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rbbp4

Associated with

Other Information

Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast. PubMed ID: 7503932

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. PubMed ID: 9702189

Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB. PubMed ID: 10866654

Identification of a nuclear domain with deacetylase activity. PubMed ID: 10984530

Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases. PubMed ID: 11788710

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. PubMed ID: 19026780

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal. PubMed ID: 28554894

PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex. PubMed ID: 34180153