Genular: Defining Cellular Identity and Function

Details for: Rbm4

Gene ID: 19653

Symbol: Rbm4

Ensembl ID: ENSMUSG00000094936

Description: RNA binding motif protein 4

Associated with

Cap-independent translational initiation
(GO:0002190)
Cell differentiation
(GO:0030154)
Circadian regulation of gene expression
(GO:0032922)
Circadian regulation of translation
(GO:0097167)
Cyclin binding
(GO:0030332)
Cytoplasm
(GO:0005737)
Cytoplasmic stress granule
(GO:0010494)
Cytosol
(GO:0005829)
Enteroendocrine cell differentiation
(GO:0035883)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Glucose homeostasis
(GO:0042593)
Insulin secretion involved in cellular response to glucose stimulus
(GO:0035773)
Ires-dependent translational initiation of linear mrna
(GO:0002192)
Metal ion binding
(GO:0046872)
Mirna-mediated gene silencing by inhibition of translation
(GO:0035278)
Mirna binding
(GO:0035198)
Mrna 3'-utr binding
(GO:0003730)
Mrna binding
(GO:0003729)
Mrna processing
(GO:0006397)
Mrna splicing, via spliceosome
(GO:0000398)
Negative regulation of translation
(GO:0017148)
Negative regulation of translational initiation
(GO:0045947)
Negative regulation of translation in response to stress
(GO:0032055)
Nuclear speck
(GO:0016607)
Nucleic acid binding
(GO:0003676)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pancreas development
(GO:0031016)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of muscle cell differentiation
(GO:0051149)
Positive regulation of translation
(GO:0045727)
Pre-mrna binding
(GO:0036002)
Pre-mrna intronic binding
(GO:0097157)
Pre-mrna intronic pyrimidine-rich binding
(GO:0097158)
Regulation of alternative mrna splicing, via spliceosome
(GO:0000381)
Regulation of gene expression
(GO:0010468)
Regulation of insulin receptor signaling pathway
(GO:0046626)
Regulation of nucleocytoplasmic transport
(GO:0046822)
Regulatory ncrna-mediated gene silencing
(GO:0031047)
Response to arsenic-containing substance
(GO:0046685)
Rna binding
(GO:0003723)
Rna splicing
(GO:0008380)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

RNA-binding protein 4
Q5CZX8_MOUSE

Genular Protein ID: 3462600293

Symbol: RBM4_MOUSE

Name: RNA-binding protein 4

UniProtKB Accession Codes:

Q8C7Q4 O08752 Q8BN66

Database IDs:

Citations:

PubMed ID: 9169144

Title: A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans.

PubMed ID: 9169144

DOI: 10.1006/geno.1997.4704

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 16260624

Title: Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB.

PubMed ID: 16260624

DOI: 10.1128/mcb.25.22.10111-10121.2005

PubMed ID: 17264215

Title: LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.

PubMed ID: 17264215

DOI: 10.1073/pnas.0607567104

PubMed ID: 19801630

Title: RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell differentiation.

PubMed ID: 19801630

DOI: 10.1074/jbc.m109.032946

PubMed ID: 21518792

Title: RBM4 down-regulates PTB and antagonizes its activity in muscle cell-specific alternative splicing.

PubMed ID: 21518792

DOI: 10.1083/jcb.201007131

Sequence Information:

Length: 361
Mass: 40046
Checksum: D50BB51553AFA4E0
Sequence:

MVKLFIGNLP REATEQEIRS LFEQYGKVLE CDIIKNYGFV HIEDKTAAED AIRNLHHYKL 
HGVNINVEAS KNKSKASTKL HVGNISPTCT NQELRAKFEE YGPVIECDIV KDYAFVHMER 
AEDAVEAIRG LDNTEFQGKR MHVQLSTSRL RTAPGMGDQS GCYRCGKEGH WSKECPIDRS 
GRVADLTEQY NEQYGAVRTP YTMSYGDSLY YNNTYGALDA YYKRCRAARS YEAVAAAAAS 
AYSNYAEQTL SQLPQVQNTA MASHLTSTSL DPYNRHLLPP SGAAAAAAAA AACTAASTSY 
YGRDRSPLRR ATGPVLTVGE GYGYGHDSEL SQASAAARNS LYDMARYERE QYADRARYSA 
F

Genular Protein ID: 3543593587

Symbol: Q5CZX8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q5CZX8

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 143
Mass: 16143
Checksum: 2167E910FBCC4616
Sequence:

MVKLFIGNLP REATEQEIRS LFEQYGKVLE CDIIKNYGFV HIEDKTAAED AIRNLHHYKL 
HGVNINVEAS KNKSKASTKL HVGNISPTCT NQELRAKFEE YGPVIECDIV KDYAFVHMER 
AEDAVEAIRG LDNTEFQGGM CVG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rbm4

Associated with

Other Information

A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans. PubMed ID: 9169144

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB. PubMed ID: 16260624

LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1. PubMed ID: 17264215

RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell differentiation. PubMed ID: 19801630

RBM4 down-regulates PTB and antagonizes its activity in muscle cell-specific alternative splicing. PubMed ID: 21518792

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303