Details for: AHSG
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hepatoblast (CL0005026)
Fold Change: 41.5715
Cell Significance Index: 699.2100 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 9.1935
Cell Significance Index: -1.4300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 6.2822
Cell Significance Index: 1246.7300 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 5.7975
Cell Significance Index: 21.8400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 5.2431
Cell Significance Index: 88.3200 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 1.7713
Cell Significance Index: 4.7500 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.7304
Cell Significance Index: 9.9700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.4438
Cell Significance Index: 21.3100 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.3698
Cell Significance Index: 19.6300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 1.1760
Cell Significance Index: -1.4500 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 1.0693
Cell Significance Index: 3.7200 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.8195
Cell Significance Index: 6.4700 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.6925
Cell Significance Index: 7.8400 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.4885
Cell Significance Index: 4.0700 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: 0.4451
Cell Significance Index: 3.4200 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.4152
Cell Significance Index: 3.8000 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.3335
Cell Significance Index: 4.6800 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.3071
Cell Significance Index: 3.0300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2545
Cell Significance Index: 6.8200 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 0.2085
Cell Significance Index: 0.5500 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.1345
Cell Significance Index: 1.7000 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.1065
Cell Significance Index: 1.1500 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.1057
Cell Significance Index: 1.0900 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.0978
Cell Significance Index: 0.9300 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0569
Cell Significance Index: 1.4200 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.0205
Cell Significance Index: 0.2900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0158
Cell Significance Index: 3.1600 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.0148
Cell Significance Index: 0.1500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0144
Cell Significance Index: 0.3700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0140
Cell Significance Index: 4.0300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0114
Cell Significance Index: 7.9000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0084
Cell Significance Index: 0.1200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0076
Cell Significance Index: 0.1300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0050
Cell Significance Index: 0.8600 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.0012
Cell Significance Index: 0.0200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0009
Cell Significance Index: 0.3400 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0001
Cell Significance Index: -0.0400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0005
Cell Significance Index: -0.9300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0006
Cell Significance Index: -1.0600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0007
Cell Significance Index: -0.9300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0008
Cell Significance Index: -1.2200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0019
Cell Significance Index: -1.3800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0024
Cell Significance Index: -1.4800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0025
Cell Significance Index: -1.4200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0029
Cell Significance Index: -2.1300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0038
Cell Significance Index: -2.4500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0043
Cell Significance Index: -1.9400 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.0043
Cell Significance Index: -0.0500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0060
Cell Significance Index: -1.0800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0071
Cell Significance Index: -1.5000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0098
Cell Significance Index: -1.1300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0100
Cell Significance Index: -0.2800 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0103
Cell Significance Index: -0.1700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0103
Cell Significance Index: -1.4200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0139
Cell Significance Index: -1.4500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0142
Cell Significance Index: -1.6500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0142
Cell Significance Index: -0.6300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0143
Cell Significance Index: -0.3900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0152
Cell Significance Index: -2.2200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0155
Cell Significance Index: -1.1900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0157
Cell Significance Index: -1.0600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0158
Cell Significance Index: -0.6000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0182
Cell Significance Index: -0.5800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0184
Cell Significance Index: -0.3600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0199
Cell Significance Index: -0.9300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0207
Cell Significance Index: -2.5500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0232
Cell Significance Index: -1.3000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0235
Cell Significance Index: -0.7700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0242
Cell Significance Index: -1.4900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0247
Cell Significance Index: -0.5700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0251
Cell Significance Index: -0.8800 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: -0.0268
Cell Significance Index: -0.3100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0271
Cell Significance Index: -2.7700 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: -0.0271
Cell Significance Index: -0.2700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0278
Cell Significance Index: -1.2600 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.0288
Cell Significance Index: -0.4200 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: -0.0293
Cell Significance Index: -0.2500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0306
Cell Significance Index: -1.3300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0324
Cell Significance Index: -2.5700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0332
Cell Significance Index: -1.2200 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: -0.0347
Cell Significance Index: -0.3600 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0348
Cell Significance Index: -0.4600 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0363
Cell Significance Index: -0.4600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0372
Cell Significance Index: -1.7500 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0387
Cell Significance Index: -0.9700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0399
Cell Significance Index: -1.1400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0421
Cell Significance Index: -1.4800 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0436
Cell Significance Index: -1.0900 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.0464
Cell Significance Index: -0.6000 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.0471
Cell Significance Index: -0.4200 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0477
Cell Significance Index: -1.5100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0479
Cell Significance Index: -1.3800 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.0484
Cell Significance Index: -0.6800 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0491
Cell Significance Index: -1.2500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0501
Cell Significance Index: -0.9900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0504
Cell Significance Index: -1.0700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0516
Cell Significance Index: -1.3800 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0526
Cell Significance Index: -1.0700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0530
Cell Significance Index: -1.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0538
Cell Significance Index: -2.8000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3221993839
Symbol: FETUA_HUMAN
Name: Alpha-2-HS-glycoprotein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3474608
Title: Human alpha 2-HS-glycoprotein: the A and B chains with a connecting sequence are encoded by a single mRNA transcript.
PubMed ID: 3474608
PubMed ID: 9322749
Title: Structure of the gene encoding human alpha 2-HS glycoprotein (AHSG).
PubMed ID: 9322749
PubMed ID: 11415520
Title: Haplotype analysis of the human alpha2-HS glycoprotein (fetuin) gene.
PubMed ID: 11415520
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3944104
Title: The complete amino acid sequence of the A-chain of human plasma alpha 2HS-glycoprotein.
PubMed ID: 3944104
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 9003486
Title: Molecular evidence for human alpha 2-HS glycoprotein (AHSG) polymorphism.
PubMed ID: 9003486
PubMed ID: 6833285
Title: Characterization of the B-chain of human plasma alpha 2HS-glycoprotein. The complete amino acid sequence and primary structure of its heteroglycan.
PubMed ID: 6833285
PubMed ID: 2645941
Title: The position of the disulfide bonds in human plasma alpha 2 HS-glycoprotein and the repeating double disulfide bonds in the domain structure.
PubMed ID: 2645941
PubMed ID: 2760061
Title: The arrangement of disulfide loops in human alpha 2-HS glycoprotein. Similarity to the disulfide bridge structures of cystatins and kininogens.
PubMed ID: 2760061
PubMed ID: 11439093
Title: Phosphorylation of human plasma alpha2-Heremans-Schmid glycoprotein (human fetuin) in vivo.
PubMed ID: 11439093
PubMed ID: 12754519
Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
PubMed ID: 12754519
DOI: 10.1038/nbt827
PubMed ID: 14760718
Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
PubMed ID: 14760718
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 19838169
Title: Enrichment of glycopeptides for glycan structure and attachment site identification.
PubMed ID: 19838169
DOI: 10.1038/nmeth.1392
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22171320
Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.
PubMed ID: 22171320
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 28054173
Title: Association of AHSG with alopecia and mental retardation (APMR) syndrome.
PubMed ID: 28054173
Sequence Information:
- Length: 367
- Mass: 39341
- Checksum: 3FE60C8D6B6272D5
- Sequence:
MKSLVLLLCL AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ NLPWGYKHTL NQIDEVKVWP QQPSGELFEI EIDTLETTCH VLDPTPVARC SVRQLKEHAV EGDCDFQLLK LDGKFSVVYA KCDSSPDSAE DVRKVCQDCP LLAPLNDTRV VHAAKAALAA FNAQNNGSNF QLEEISRAQL VPLPPSTYVE FTVSGTDCVA KEATEAAKCN LLAEKQYGFC KATLSEKLGG AEVAVTCMVF QTQPVSSQPQ PEGANEAVPT PVVDPDAPPS PPLGAPGLPP AGSPPDSHVL LAAPPGHQLH RAHYDLRHTF MGVVSLGSPS GEVSHPRKTR TVVQPSVGAA AGPVVPPCPG RIRHFKV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.