AHSG | ENSG00000145192 | NCBI 197

Details for: AHSG

Gene ID: 197

Symbol: AHSG

Ensembl ID: ENSG00000145192

Description: alpha 2-HS glycoprotein

Associated with

Hemostasis
(R-HSA-109582)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Metabolism of proteins
(R-HSA-392499)
Neutrophil degranulation
(R-HSA-6798695)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Platelet degranulation
(R-HSA-114608)
Post-translational protein modification
(R-HSA-597592)
Post-translational protein phosphorylation
(R-HSA-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-HSA-381426)
Response to elevated platelet cytosolic ca2+
(R-HSA-76005)
Acute-phase response
(GO:0006953)
Blood microparticle
(GO:0072562)
Collagen-containing extracellular matrix
(GO:0062023)
Cysteine-type endopeptidase inhibitor activity
(GO:0004869)
Endopeptidase inhibitor activity
(GO:0004866)
Endoplasmic reticulum lumen
(GO:0005788)
Extracellular exosome
(GO:0070062)
Extracellular matrix
(GO:0031012)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Kinase inhibitor activity
(GO:0019210)
Negative regulation of bone mineralization
(GO:0030502)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of insulin receptor signaling pathway
(GO:0046627)
Ossification
(GO:0001503)
Pinocytosis
(GO:0006907)
Platelet alpha granule lumen
(GO:0031093)
Positive regulation of phagocytosis
(GO:0050766)
Regulation of bone mineralization
(GO:0030500)
Regulation of inflammatory response
(GO:0050727)
Secretory granule lumen
(GO:0034774)
Skeletal system development
(GO:0001501)

Other Information

Proteins

Alpha-2-HS-glycoprotein

Genular Protein ID: 3221993839

Symbol: FETUA_HUMAN

Name: Alpha-2-HS-glycoprotein

UniProtKB Accession Codes:

P02765 A8K9N6 B2R7G1 O14961 O14962 Q9P152

Database IDs:

Citations:

PubMed ID: 3474608

Title: Human alpha 2-HS-glycoprotein: the A and B chains with a connecting sequence are encoded by a single mRNA transcript.

PubMed ID: 3474608

DOI: 10.1073/pnas.84.13.4403

PubMed ID: 9322749

Title: Structure of the gene encoding human alpha 2-HS glycoprotein (AHSG).

PubMed ID: 9322749

DOI: 10.1016/s0378-1119(97)00216-3

PubMed ID: 11415520

Title: Haplotype analysis of the human alpha2-HS glycoprotein (fetuin) gene.

PubMed ID: 11415520

DOI: 10.1046/j.1469-1809.2001.6510027.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3944104

Title: The complete amino acid sequence of the A-chain of human plasma alpha 2HS-glycoprotein.

PubMed ID: 3944104

DOI: 10.1016/s0021-9258(17)35992-6

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 9003486

Title: Molecular evidence for human alpha 2-HS glycoprotein (AHSG) polymorphism.

PubMed ID: 9003486

DOI: 10.1007/s004390050302

PubMed ID: 6833285

Title: Characterization of the B-chain of human plasma alpha 2HS-glycoprotein. The complete amino acid sequence and primary structure of its heteroglycan.

PubMed ID: 6833285

DOI: 10.1016/s0021-9258(18)32522-5

PubMed ID: 2645941

Title: The position of the disulfide bonds in human plasma alpha 2 HS-glycoprotein and the repeating double disulfide bonds in the domain structure.

PubMed ID: 2645941

DOI: 10.1016/0167-4838(89)90293-8

PubMed ID: 2760061

Title: The arrangement of disulfide loops in human alpha 2-HS glycoprotein. Similarity to the disulfide bridge structures of cystatins and kininogens.

PubMed ID: 2760061

DOI: 10.1016/s0021-9258(18)71651-7

PubMed ID: 11439093

Title: Phosphorylation of human plasma alpha2-Heremans-Schmid glycoprotein (human fetuin) in vivo.

PubMed ID: 11439093

DOI: 10.1042/0264-6021:3570437

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22171320

Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.

PubMed ID: 22171320

DOI: 10.1074/mcp.m111.013649

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 28054173

Title: Association of AHSG with alopecia and mental retardation (APMR) syndrome.

PubMed ID: 28054173

DOI: 10.1007/s00439-016-1756-5

Sequence Information:

Length: 367
Mass: 39341
Checksum: 3FE60C8D6B6272D5
Sequence:

MKSLVLLLCL AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ NLPWGYKHTL 
NQIDEVKVWP QQPSGELFEI EIDTLETTCH VLDPTPVARC SVRQLKEHAV EGDCDFQLLK 
LDGKFSVVYA KCDSSPDSAE DVRKVCQDCP LLAPLNDTRV VHAAKAALAA FNAQNNGSNF 
QLEEISRAQL VPLPPSTYVE FTVSGTDCVA KEATEAAKCN LLAEKQYGFC KATLSEKLGG 
AEVAVTCMVF QTQPVSSQPQ PEGANEAVPT PVVDPDAPPS PPLGAPGLPP AGSPPDSHVL 
LAAPPGHQLH RAHYDLRHTF MGVVSLGSPS GEVSHPRKTR TVVQPSVGAA AGPVVPPCPG 
RIRHFKV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AHSG

Associated with

Other Information

Human alpha 2-HS-glycoprotein: the A and B chains with a connecting sequence are encoded by a single mRNA transcript. PubMed ID: 3474608

Structure of the gene encoding human alpha 2-HS glycoprotein (AHSG). PubMed ID: 9322749

Haplotype analysis of the human alpha2-HS glycoprotein (fetuin) gene. PubMed ID: 11415520

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The complete amino acid sequence of the A-chain of human plasma alpha 2HS-glycoprotein. PubMed ID: 3944104

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. PubMed ID: 12665801

Molecular evidence for human alpha 2-HS glycoprotein (AHSG) polymorphism. PubMed ID: 9003486

Characterization of the B-chain of human plasma alpha 2HS-glycoprotein. The complete amino acid sequence and primary structure of its heteroglycan. PubMed ID: 6833285

The position of the disulfide bonds in human plasma alpha 2 HS-glycoprotein and the repeating double disulfide bonds in the domain structure. PubMed ID: 2645941

The arrangement of disulfide loops in human alpha 2-HS glycoprotein. Similarity to the disulfide bridge structures of cystatins and kininogens. PubMed ID: 2760061

Phosphorylation of human plasma alpha2-Heremans-Schmid glycoprotein (human fetuin) in vivo. PubMed ID: 11439093

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. PubMed ID: 12754519

Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. PubMed ID: 14760718

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. PubMed ID: 16740002

Phosphoproteome of resting human platelets. PubMed ID: 18088087

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography. PubMed ID: 18318008

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

A strategy for precise and large scale identification of core fucosylated glycoproteins. PubMed ID: 19139490

Enrichment of glycopeptides for glycan structure and attachment site identification. PubMed ID: 19838169

Initial characterization of the human central proteome. PubMed ID: 21269460

Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD. PubMed ID: 22171320

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

A single kinase generates the majority of the secreted phosphoproteome. PubMed ID: 26091039

Association of AHSG with alopecia and mental retardation (APMR) syndrome. PubMed ID: 28054173