Details for: Ret

Gene ID: 19713

Symbol: Ret

Ensembl ID: ENSMUSG00000030110

Description: ret proto-oncogene

Associated with

Other Information

Genular Protein ID: 1700974165

Symbol: RET_MOUSE

Name: Proto-oncogene tyrosine-protein kinase receptor Ret

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8455936

Title: cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily.

PubMed ID: 8455936

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8631863

Title: Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7.

PubMed ID: 8631863

DOI: 10.1074/jbc.271.18.10607

PubMed ID: 11470823

Title: Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.

PubMed ID: 11470823

DOI: 10.1083/jcb.200102032

PubMed ID: 17322904

Title: Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis.

PubMed ID: 17322904

DOI: 10.1038/nature05597

PubMed ID: 18753381

Title: CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.

PubMed ID: 18753381

DOI: 10.1523/jneurosci.2738-08.2008

PubMed ID: 20237269

Title: RET signaling is required for survival and normal function of nonpeptidergic nociceptors.

PubMed ID: 20237269

DOI: 10.1523/jneurosci.5930-09.2010

PubMed ID: 21134556

Title: A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo.

PubMed ID: 21134556

DOI: 10.1016/j.surg.2010.09.026

PubMed ID: 28953886

Title: Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.

PubMed ID: 28953886

DOI: 10.1038/nature24042

PubMed ID: 29144449

Title: Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.

PubMed ID: 29144449

DOI: 10.1038/nature24481

PubMed ID: 28846099

Title: GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.

PubMed ID: 28846099

DOI: 10.1038/nm.4394

PubMed ID: 14607833

Title: Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain.

PubMed ID: 14607833

DOI: 10.1074/jbc.m311030200

Sequence Information:

  • Length: 1115
  • Mass: 123874
  • Checksum: A5CF1EF45A640413
  • Sequence:
  • MAKATSGAAG LGLKLILLLP LLGEAPLGLY FSRDAYWERL YVDQPAGTPL LYVHALRDAP 
    GEVPSFRLGQ HLYGVYRTRL HENDWIRINE TTGLLYLNQS LDHSSWEQLS IRNGGFPLLT 
    IFLQVFLGST AQREGECHWP GCTRVYFSFI NDTFPNCSSF KAQDLCIPET AVSFRVRENR 
    PPGTFYHFHM LPVQFLCPNI SVKYSLLGGD SLPFRCDPDC LEVSTRWALD RELREKYVLE 
    ALCIVAGPGA NKETVTLSFP VTVYDEDDSA PTFSGGVGTA SAVVEFKRKE GTVVATLQVF 
    DADVVPASGE LVRRYTNTLL SGDSWAQQTF RVEHSPIETL VQVNNNSVRA TMHNYKLILN 
    RSLSISESRV LQLAVLVNDS DFQGPGAGGI LVLHFNVSVL PVTLNLPRAY SFPVNKRARR 
    YAQIGKVCVE NCQEFSGVSI QYKLQPSSIN CTALGVVTSP EDTSGTLFVN DTEALRRPEC 
    TKLQYTVVAT DRQTRRQTQA SLVVTVEGTS ITEEVGCPKS CAVNKRRPEC EECGGLGSPT 
    GRCEWRQGDG KGITRNFSTC SPSTRTCPDG HCDAVESRDA NICPQDCLRA DIVGGHERGE 
    RQGIKAGYGI CNCFPDEKKC FCEPEDSQGP LCDALCRTII TAALFSLIIS ILLSIFCVCH 
    HHKHGHKPPI ASAEMTFCRP AQGFPISYSS SGTRRPSLDS TENQVPVDSF KIPEDPKWEF 
    PRKNLVLGKT LGEGEFGKVV KATAFRLKGR AGYTTVAVKM LKENASQSEL RDLLSEFNLL 
    KQVNHPHVIK LYGACSQDGP LLLIVEYAKY GSLRGFLRDS RKIGPAYVSG GGSRNSSSLD 
    HPDERVLTMG DLISFAWQIS RGMQYLAEMK LVHRDLAARN ILVAEGRKMK ISDFGLSRDV 
    YEEDSYVKKS KGRIPVKWMA IESLFDHIYT TQSDVWSFGV LLWEIVTLGG NPYPGIPPER 
    LFNLLKTGHR MERPDNCSEE MYRLMLQCWK QEPDKRPVFA DISKDLEKMM VKSRDYLDLA 
    ASTPSDSLLY DDGLSEEETP LVDCNNAPLP RSLPSTWIEN KLYGMSDPNW PGESPVPLTR 
    ADGTSTGFPR YANDSVYANW MVSPSAAKLM DTFDS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.