Genular: Defining Cellular Identity and Function

Details for: Rfc2

Gene ID: 19718

Symbol: Rfc2

Ensembl ID: ENSMUSG00000023104

Description: replication factor C (activator 1) 2

Associated with

Activation of atr in response to replication stress
(R-MMU-176187)
Base excision repair
(R-MMU-73884)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Chromosome maintenance
(R-MMU-73886)
Dna damage bypass
(R-MMU-73893)
Dna double-strand break repair
(R-MMU-5693532)
Dna strand elongation
(R-MMU-69190)
Dual incision in gg-ner
(R-MMU-5696400)
Dual incision in tc-ner
(R-MMU-6782135)
Extension of telomeres
(R-MMU-180786)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
Gap-filling dna repair synthesis and ligation in gg-ner
(R-MMU-5696397)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-MMU-6782210)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Hdr through homologous recombination (hrr)
(R-MMU-5685942)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Hdr through single strand annealing (ssa)
(R-MMU-5685938)
Homology directed repair
(R-MMU-5693538)
Lagging strand synthesis
(R-MMU-69186)
Leading strand synthesis
(R-MMU-69109)
Nucleotide excision repair
(R-MMU-5696398)
Pcna-dependent long patch base excision repair
(R-MMU-5651801)
Polymerase switching
(R-MMU-69091)
Polymerase switching on the c-strand of the telomere
(R-MMU-174411)
Processing of dna double-strand break ends
(R-MMU-5693607)
Recognition of dna damage by pcna-containing replication complex
(R-MMU-110314)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through phosphorylation
(R-MMU-6804756)
Resolution of abasic sites (ap sites)
(R-MMU-73933)
Resolution of ap sites via the multiple-nucleotide patch replacement pathway
(R-MMU-110373)
Rna polymerase ii transcription
(R-MMU-73857)
S phase
(R-MMU-69242)
Synthesis of dna
(R-MMU-69239)
Telomere c-strand (lagging strand) synthesis
(R-MMU-174417)
Telomere maintenance
(R-MMU-157579)
Termination of translesion dna synthesis
(R-MMU-5656169)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-MMU-6781827)
Transcriptional regulation by tp53
(R-MMU-3700989)
Translesion synthesis by polh
(R-MMU-110320)
Translesion synthesis by poli
(R-MMU-5656121)
Translesion synthesis by polk
(R-MMU-5655862)
Translesion synthesis by rev1
(R-MMU-110312)
Translesion synthesis by y family dna polymerases bypasses lesions on dna template
(R-MMU-110313)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Ctf18 rfc-like complex
(GO:0031390)
Dna-templated dna replication
(GO:0006261)
Dna binding
(GO:0003677)
Dna clamp loader activity
(GO:0003689)
Dna repair
(GO:0006281)
Dna replication
(GO:0006260)
Dna replication factor c complex
(GO:0005663)
Enzyme binding
(GO:0019899)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Positive regulation of dna-directed dna polymerase activity
(GO:1900264)
Single-stranded dna helicase activity
(GO:0017116)

Other Information

Proteins

Replication factor C subunit 2

Genular Protein ID: 926108110

Symbol: RFC2_MOUSE

Name: Replication factor C subunit 2

UniProtKB Accession Codes:

Q9WUK4

Database IDs:

Citations:

PubMed ID: 11003705

Title: Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human chromosome 7q11.23.

PubMed ID: 11003705

DOI: 10.1007/s003350010166

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 349
Mass: 38725
Checksum: 62BB552004CCA27F
Sequence:

MEVQESGCDP SESGAQEPSP VPSKTAGHYE LPWVEKYRPL KLNEIVGNED TVSRLEVFAR 
EGNVPNIIIA GPPGTGKTTS ILCLARALLG PALKDAVLEL NASNDRGIDV VRNKIKMFAQ 
QKVTLPKGRH KIIILDEADS MTDGAQQALR RTMEIYSKTT RFALACNASD KIIEPIQSRC 
AVLRYTKLTD AQVLTRLMNV IEKEKVPYTD DGLEAIIFTA QGDMRQALNN LQSTFSGFGY 
INSENVFKVC DEPHPLLVKE MIQHCVDANI DEAYKILAHL WHLGYSPEDV IGNIFRVCKT 
FPMAEYLKLE FIKEIGYTHM KVAEGVNSLL QMAGLLARLC QKTMAPVAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rfc2

Associated with

Other Information

Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human chromosome 7q11.23. PubMed ID: 11003705

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 11003705

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 21183079