Genular: Defining Cellular Identity and Function

Details for: Trim27

Gene ID: 19720

Symbol: Trim27

Ensembl ID: ENSMUSG00000021326

Description: tripartite motif-containing 27

Associated with

Intracellular signaling by second messengers
(R-MMU-9006925)
Metabolism of proteins
(R-MMU-392499)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Pten regulation
(R-MMU-6807070)
Regulation of pten stability and activity
(R-MMU-8948751)
Signal transduction
(R-MMU-162582)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of ubiquitinylation proteins
(R-MMU-3232142)
Arp2/3 complex-mediated actin nucleation
(GO:0034314)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Endosome
(GO:0005768)
Fibrillar center
(GO:0001650)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Negative regulation of adaptive immune response
(GO:0002820)
Negative regulation of autophagy
(GO:0010507)
Negative regulation of calcium ion import
(GO:0090281)
Negative regulation of gene expression, epigenetic
(GO:0045814)
Negative regulation of interleukin-2 production
(GO:0032703)
Negative regulation of protein kinase activity
(GO:0006469)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Negative regulation of type i interferon production
(GO:0032480)
Negative regulation of viral transcription
(GO:0032897)
Nuclear membrane
(GO:0031965)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of actin nucleation
(GO:0051127)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of type ii interferon production
(GO:0032729)
Protein binding
(GO:0005515)
Protein k63-linked ubiquitination
(GO:0070534)
Retrograde transport, endosome to golgi
(GO:0042147)
Retromer complex
(GO:0030904)
Sumo transferase activity
(GO:0019789)
Suppression of viral release by host
(GO:0044790)
Transcription coactivator activity
(GO:0003713)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Zinc finger protein RFP

Genular Protein ID: 991112344

Symbol: TRI27_MOUSE

Name: Zinc finger protein RFP

UniProtKB Accession Codes:

Q62158 Q62157 Q8C2Q5 Q99LK1

Database IDs:

Citations:

PubMed ID: 9023983

Title: Mouse ret finger protein (rfp) proto-oncogene is expressed at specific stages of mouse spermatogenesis.

PubMed ID: 9023983

DOI: 10.1002/(sici)1520-6408(1996)19:4<309::aid-dvg4>3.0.co;2-d

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1437549

Title: RFP is a DNA binding protein associated with the nuclear matrix.

PubMed ID: 1437549

DOI: 10.1093/nar/20.20.5305

PubMed ID: 10571821

Title: Different nuclear/cytoplasmic distributions of RET finger protein in different cell types.

PubMed ID: 10571821

DOI: 10.1046/j.1440-1827.1999.00957.x

PubMed ID: 24144979

Title: Ubiquitination-deubiquitination by the TRIM27-USP7 complex regulates tumor necrosis factor alpha-induced apoptosis.

PubMed ID: 24144979

DOI: 10.1128/mcb.00465-13

PubMed ID: 26365382

Title: USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder.

PubMed ID: 26365382

DOI: 10.1016/j.molcel.2015.07.033

Sequence Information:

Length: 513
Mass: 58513
Checksum: 9384B6678352A434
Sequence:

MASGSVAECL QQETTCPVCL QYFVEPMMLD CGHNICCACL ARCWGAAETN VSCPQCRETF 
PQRHMRPNRH LANVTQLVKQ LRTERPSGPG GEMGVCEKHR EPLKLYCEQD QMPICVVCDR 
SREHRGHSVL PLEEAVEGFK EQIQNRLDHL RRVKDLKKRR RAQGEQARAE LLSLTQMERE 
KIVWEFEQLY HSLKEHEYRL LARLEELDLA IYNSINGAIT QFSCNISHLS GLIAQLEEKQ 
QQPTRELLQD IGDTLSRAER IRIPEPWITP PDLQEKIHIF AQKCLFLTES LKQFTEKMQS 
DMEKIQELRE AQLYSVDVTL DPDTAYPSLI LSDNLRQVRY SYLQQDLPDN PERFNLFPCV 
LGSPCFIAGR HYWEVEVGDK AKWTIGVCED SVCRKGGVTS APQNGFWAVS LWYGKEYWAL 
TSPMTALPLR TPLQRVGIFL DYDAGEVSFY NVTERCHTFT FSHATFCGPV RPYFSLSYSG 
GKSAAPLIIC PMSGIDGFSG HVGNHGHSME TSP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Trim27

Associated with

Other Information

Mouse ret finger protein (rfp) proto-oncogene is expressed at specific stages of mouse spermatogenesis. PubMed ID: 9023983

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

RFP is a DNA binding protein associated with the nuclear matrix. PubMed ID: 1437549

Different nuclear/cytoplasmic distributions of RET finger protein in different cell types. PubMed ID: 10571821

Ubiquitination-deubiquitination by the TRIM27-USP7 complex regulates tumor necrosis factor alpha-induced apoptosis. PubMed ID: 24144979

USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder. PubMed ID: 26365382